个人简介

Mike Porter is a Senior Lecturer in the Organic Chemistry/Chemical Biology section of the Department of Chemistry. Research within his group focuses on the development of new methods for the synthesis of biologically active compounds, and the chemistry developed includes metal carbenoid reactions, novel sulfur chemistry, and sigmatropic rearrangements. Other research includes the preparation of antibacterial polymer surfaces (in collaboration with Prof Parkin), and computational studies into reaction mechanisms. He has worked at UCL since 1999 (1999-2006: Lecturer; 2006- Senior Lecturer). Prior to this he had postdoctoral appointments at the University of Texas at Austin, working with Professor Philip Magnus, and at the University of Liverpool, working with Professor Stan Roberts. He received his DPhil from the University of Oxford, under the supervision of Professor Sir Jack Baldwin.

研究领域

Organic Chemistry and Chemical Biology

Natural Product Synthesis Carbenoid Chemistry Sulfur Chemistry Asymmetric Synthesis Carbohydrates Photochemistry Computational Chemistry

近期论文

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Parkes, M. A., Phillips, C., Porter, M. J., & Fielding, H. H. (2016). Controlling electron emission from the photoactive yellow protein chromophore by substitution at the coumaric acid group. Physical chemistry chemical physics : PCCP, 18 (15), 10329-10336. Peveler, W. J., Roldan, A., Hollingsworth, N., Porter, M. J., & Parkin, I. P. (2016). Multichannel Detection and Differentiation of Explosives with a Quantum Dot Array. ACS NANO, 10 (1), 1139-1146. doi:10.1021/acsnano.5b06433 Aliev, A. E., Karu, K., Mitchell, R. E., & Porter, M. J. (2016). The structure of tagetitoxin. ORGANIC & BIOMOLECULAR CHEMISTRY, 14 (1), 238-245. doi:10.1039/c5ob02076j Aliev, A. E., Arendorf, J. R. T., Pavlakos, I., Moreno, R. B., Porter, M. J., Rzepa, H. S., & Motherwell, W. B. (2015). Surfing pi Clouds for Noncovalent Interactions: Arenes versus Alkenes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 54 (2), 551-555. doi:10.1002/anie.201409672 Chavda, J. K., Procopiou, P. A., Horton, P. N., Coles, S. J., & Porter, M. J. (2014). Synthetic Studies Towards the Core Structure of Nakadomarin A by a Thioamide-Based Strategy. European Journal Of Organic Chemistry, 2014 (1), 129-139. doi:10.1002/ejoc.201301063 Porter, M. J., Price Mortimer, A. J. P., Goodman, J. P., & Ellwood, A. R. (2013). Reversal of facial selectivity in a thia-Claisen rearrangement by incorporation of a vinylic bromine substituent. Org. Biomol. Chem., 11, 7530-?. doi:10.1039/C3OB41580E Anderson, J. C., Kalogirou, A. S., Porter, M. J., & Tizzard, G. J. (2013). Synthesis of the reported structure of piperazirum using a nitro-Mannich reaction as the key stereochemical determining step. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 9. doi:10.3762/bjoc.9.200 Porter, M. J., Mortimer, A. J. P., Plet, J. R. H., obasanjo, O., & kaltsoyannis, N. (2012). Inter- and intramolecular reactions of 1-deoxy-1-thio-1,6-anhydrosugars with α-diazoesters: synthesis of the tagetitoxin core by photochemical ylide rearrangement. Organic and Biomolecular Chemistry, 10, 8616-8627. doi:10.1039/C2OB26308D Ellwood, A. R., & Porter, M. J. (2011). A direct and efficient preparation of 1-phenyltetrazol-5-yl sulfides from alcohols. ORGANIC & BIOMOLECULAR CHEMISTRY, 9 (2), 379-381. doi:10.1039/c0ob00863j Ellwood, A. R., & Porter, M. J. (2010). Spin-offs from synthesis: Thia-Claisen rearrangement and alcohol iodination. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 239. Bruce, I. E., Mehta, L., Porter, M. J., Stein, B. K., & Tyman, J. H. P. (2009). Anionic Surfactants Synthesised from Replenishable Phenolic Lipids. JOURNAL OF SURFACTANTS AND DETERGENTS, 12 (4), 337-344. doi:10.1007/s11743-009-1116-8 PORTER, M., & Skidmore, J. (2009). Asymmetric epoxidation of electron-deficient alkenes. In S. E. Denmark (Ed.), Organic reactions (pp. 425-672). Hoboken, New Jersey, US: Wiley. Ellwood, A. R., & Porter, M. J. (2009). Selective Conversion of Alcohols into Alkyl Iodides Using a Thioiminium Salt. JOURNAL OF ORGANIC CHEMISTRY, 74 (20), 7982-7985. doi:10.1021/jo901415n Plet, J. R. H., Sandhu, A. K., Sehailia, M., & Porter, M. J. (2009). Thieme Chemistry Journal Awardees - Where Are They Now? Approaches to Tagetitoxin and its Decarboxy Analogue from D-Glucose. SYNLETT (20), 3258-3262. doi:10.1055/s-0029-1218525 Mortimer, A. J. P., Pang, P. S., Aliev, A. E., Tocher, D. A., & Porter, M. J. (2008). Concise synthesis of bicyclic aminals and their evaluation as precursors to the sarain core. Organic and Biomolecular Chemistry, 6, 2941-2951. doi:10.1039/b806031b Ellwood, A. R., Mortimer, A. J. P., Tocher, D. A., & Porter, M. J. (2008). Diastereoselective Thia-Claisen rearrangement of pyrrolidinone-derived ketene N,S-acetals. SYNLETT (14), 2199-2203. doi:10.1055/s-2008-1078030 Mortimer, A. J. P., Aliev, A. E., Tocher, D. A., & Porter, M. J. (2008). Synthesis of the Tagetitoxin Core via Photo-Stevens Rearrangement. Organic Letters, 10 (23), 5477-5480. doi:10.1021/ol802297h PORTER, M. (2007). Alkanols: synthesis by oxidation. In J. Clayden (Ed.), Science of synthesis (pp. 17-54). Stuttgart, Germany: Georg Thieme Verlag. PORTER, M. (2007). Benzylic alcohols. In J. Clayden (Ed.), Science of synthesis (pp. 573-582). Stuttgart, Germany: Georg Thieme Verlag. Ishaq, S., & Porter, M. J. (2006). Allylsilyl Propargyl Ethers as Substrates for Intramolecular Pauson-Khand Reactions. Synthetic Communications, 36, 547-557. Porter, M. J., Saez, F., & Sandhu, A. K. (2006). Direct conversion of tert-butyl 2-hydroxyalkyl sulfides to 1,3-oxathiolanes. Tetrahedron, 62, 931-936. doi:10.1016/j.tet.2005.10.026 Plet, J. R. H., & Porter, M. J. (2006). Synthesis of the Bicyclic Core of Tagetitoxin. Chemical Communications (11), 1197-1199. doi:10.1039/b600819d Ioannou, M., Porter, M. J., & Saez, F. (2005). Conversion of 1,3-Oxathiolanes to 1,4-Oxathianes using a Silylated Diazoester. Tetrahedron, 61, 43-50. Nandra, G. S., Porter, M. J., & Elliott, J. M. (2005). Reductive Cyclisation of Azidolactams with Bu3P/LiAlH4. Synthesis, 475-479. Nandra, G. S., Pang, P. S., Porter, M. J., & Elliott, J. M. (2005). Synthesis of Vinylogous Carbamates by Rhodium(II)-Catalyzed Olefination of Tertiary Formamides with a Silylated Diazoester. Organic Letters, 7, 3453-3455. doi:10.1021/ol0510872