Evans, Katie - Liverpool John Moores University - School of Pharmacy and Biomolecular Sciences

个人简介

I gained my first degree, a BSc (Hons) in Applied Microbiology, from LJMU in 2001. After completing my undergraduate degree I spent some time working in industry at one of the largest pharmaceutical companies in the world and then at a water treatment company carrying out analysis and testing for Legionella. I then studied for my PhD not too far away from Liverpool at the STFC Daresbury Laboratory (then home to the synchrotron radiation source). My PhD focussed on characterisation of bacteriophytochromes in the purple bacterium Rhodopseudomonas palustris. After my PhD, wanting to explore further afield, I accepted a postdoctoral position at Texas A&M University. I worked in the department of Microbial and Molecular Pathogenesis, investigating virulence mechanisms in Mycobacterium tuberculosis. It was here that I found my niche in medical microbiology. Following my postdoc, I moved back to Liverpool and took a position working for a clinical diagnostics company. Here I developed phenotypic tests to detect Enterobacteriaceae producing extended-spectrum beta-lactamase enzymes, a significant cause of multidrug-resistant infections. In 2009 I joined LJMU School of Pharmacy and Biomolecular Sciences as a lecturer in Microbiology. I teach general and medical microbiology across a range of programmes including Biomedical Science, Biochemistry, Biology and Pharmacy.

研究领域

• Bacterial pathogenesis and antimicrobial resistance • Development of diagnostic tests for antimicrobial resistance genes • Photodynamic therapy in the treatment of microbial infections

近期论文

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Teethaisong Y, Eumkeb G, Chumnarnsilpa S, Autarkool N, Hobson J, Nakouti I, Hobbs G, Evans K. 2016. Phenotypic detection of AmpC beta-lactamases, extended-spectrum beta-lactamases and metallo-beta-lactamases in Enterobacteriaceae using a resazurin microtitre assay with inhibitor-based methods JOURNAL OF MEDICAL MICROBIOLOGY, 65 :1079-1087 >DOI >Link Teethaisong Y, Eumkeb G, Nakouti I, Evans K, Hobbs G. 2016. A combined disc method with resazurin agar plate assay for early phenotypic screening of KPC, MBL and OXA-48 carbapenemases among Enterobacteriaceae JOURNAL OF APPLIED MICROBIOLOGY, 121 :408-414 >DOI >Link Zhuang Q, Smallman H, Lambert SJ, Sodngam SS, Reynolds CD, Evans K, Dickman MJ, Baldwin JP, Wood CM. 2014. Cofractionation of HMGB proteins with histone dimers. Anal Biochem, 447 :98-106 >DOI >Link Foulger LE, Sin CGT, Zhuang QQ, Smallman H, Nicholson JM, Lambert SJ, Reynolds CD, Dickman MJ, Wood CM, Baldwin JP, Evans K. 2012. Efficient purification of chromatin architectural proteins: histones, HMGB proteins and FKBP3 (FKBP25) immunophilin RSC ADVANCES, 2 :10598-10604 >DOI >Link Derbyshire H, Kay G, Evans K, Vaughan C, Kavuri U, Winstanley T. 2009. A simple disc diffusion method for detecting AmpC and extended-spectrum beta-lactamases in clinical isolates of Enterobacteriaceae JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 63 :497-501 >DOI >Link Evans K, Grossmann JG, Fordham-Skelton AP, Papiz MZ. 2006. Small Angle X-ray Scattering Reveals the Solution Structure of a Bacteriophytochrome in the Catalytically Active Pr State Journal of Molecular Biology, 364 :655-666 Evans K, Fordham-Skelton AP, Mistry H, Reynolds CD, Lawless AM, Papiz MZ. 2005. A bacteriophytochrome regulates the synthesis of LH4 complexesin Rhodopseudomonas palustris PHOTOSYNTHESIS RESEARCH, 85 :169-180 >DOI >Link Evans K, Georgiou T, Hillon T, Fordham-Skelton AP, Papiz MZ. 2008. The Purple Phototrophic Bacteria Hunter CN, Daldal F, Thurnauer MC. The Purple Phototrophic Bacteria Springer Verlag 9781402088148