Rayne, Richard C - Birkbeck, University of London - Department of Biological Sciences

研究领域

My interests cover a range of topics which normally can be grouped under the heading 'cell signalling systems in invertebrates' and I tend to approach research questions from the perspective of a biochemist/cell biologist. Most recently, I have been interested in how phagocytosis contributes to cell-mediated immunity, using a model insect, Manduca sexta. We have been examining phagocytosis of bacteria in vitro with a view to understanding the cellular and biochemical mechanisms by which the phenomenon is initiated and regulated.

近期论文

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de Winter P, Rayne RC, and Coast GM (2007) The effects of intracellular signalling pathway inhibitors on phagocytosis by haemocytes of Manduca sexta. J Insect Physiol. 53 (10), 975-982. Cash D, Beech JS, Rayne RC, Bath PMW, Meldrum BS, and Williams SCR (2001) Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Research 905(1-2), 91-103. Lam W, Coast GM, and Rayne RC (2000) Characterisation of multiple trypsins from the midgut of Locusta migratoria. Insect Biochem. Molec. Biol. 30 (1), 85-94. Cash D., Beech J.S., Rayne R.C., Bath P.M.W., Meldrum B.S., and Williams S.C.R. (2001) Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Research 905(1-2), 91-103. Lam, W., Coast, G.M. and Rayne, R.C. (2000) Characterisation of multiple trypsins from the midgut of Locusta migratoria. Insect Biochem. Molec. Biol. 30 (1), 85-94.