Lowe, Alan - Birkbeck, University of London - Department of Biological Sciences

个人简介

2005 PhD Doctor of Philosophy – Biophysics University of Cambridge 2001 M. Biochem Hons Master of Biochemistry (Honours) – Biochemistry University of Bath

近期论文

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Schuergers, N., Lenn, T., Kampmann, R., Meissner, M. V., Esteves, T., Temerinac-Ott, M., . . . Wilde, A. (2016). Cyanobacteria use micro-optics to sense light direction. ELIFE, 5, ARTN e12620. doi:10.7554/eLife.12620 Lowe, A. R., Tang, J. H., Yassif, J., Graf, M., Huang, W. Y. C., Groves, J. T., . . . Liphardt, J. T. (2015). Importin-beta modulates the permeability of the nuclear pore complex in a Ran-dependent manner. ELIFE, 4, ARTN e04052. doi:10.7554/eLife.04052 Lowe, A. R., Siegel, J. J., Kalab, P., Siu, M., Weis, K., & Liphardt, J. T. (2010). Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking. Nature, 467, 600-603. doi:10.1038/nature09285 Perdios, P., Lowe, A. R., Saladino, G., Bunney, D. T., Thiyagarajan, N., Alexandrov, Y., . . . Katan, M. (2017). Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET. Scientific Reports. Jeremy, G., Stevens, J., & Lowe, A. R. (2016). Single-Molecule Imaging to Characterize the Transport Mechanism of the Nuclear Pore Complex. Methods in molecular biology (Clifton, N.J.), 1431, 17-35. Hutton, R. D., Wilkinson, J., Faccin, M., Sivertsson, D. M., Pelizzola, A., Lowe, A. R., . . . Itzhaki, L. S. (2015). Mapping the Topography of a Protein Energy Landscape. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137 (46), 14610-14625. doi:10.1021/jacs.5b07370 Tang, J. H., Lowe, A. R., Yassif, J., Graf, M., Huang, W. Y. C., Groves, J. T., . . . Liphardt, J. T. (2014). A Ran-Dependent Importin-Beta/Nup153 Barrier in the Nuclear Pore Complex. BIOPHYSICAL JOURNAL, 106 (2), 312A. Itzhaki, L. S., & Lowe, A. R. (2012). From artificial antibodies to nanosprings: the biophysical properties of repeat proteins. Adv Exp Med Biol, 747, 153-166. doi:10.1007/978-1-4614-3229-6_10 Moreau, M. J., McGeoch, A. T., Lowe, A. R., Itzhaki, L. S., & Bell, S. D. (2007). ATPase site architecture and helicase mechanism of an archaeal MCM. Mol Cell, 28, 304-314. doi:10.1016/j.molcel.2007.08.013 Lowe, A. R., & Itzhaki, L. S. (2007). Biophysical characterisation of the small ankyrin repeat protein myotrophin. J Mol Biol, 365, 1245-1255. doi:10.1016/j.jmb.2006.10.060 Lowe, A. R., & Itzhaki, L. S. (2007). Rational redesign of the folding pathway of a modular protein. Proc Natl Acad Sci U S A, 104, 2679-2684. doi:10.1073/pnas.0604653104 Main, E. R., Lowe, A. R., Mochrie, S. G., Jackson, S. E., & Regan, L. (2005). A recurring theme in protein engineering: the design, stability and folding of repeat proteins. Curr Opin Struct Biol, 15, 464-471. doi:10.1016/j.sbi.2005.07.003 Lowe, C. R., Lowe, A. R., & Gupta, G. (2001). New developments in affinity chromatography with potential application in the production of biopharmaceuticals. J Biochem Biophys Methods, 49, 561-574.