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Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury Journal article; 2009; Journal of Clinical Investigation Links: IRIS | UCL Discovery | Author's Authors: Scotton CJ,Krupiczojc MA,Koenigshoff M,Mercer PF,Lee YCG,Kaminski N,Morser J,Post JM,Maher TM,Nicholson AG,Moffatt JD,Laurent GJ,Derian CK,Eickelberg O,Chambers RC click to collapse Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Journal article; 2007; Chest Links: IRIS | UCL Discovery | DOI Authors: Scotton CJ,Chambers RC click to collapse Epithelial cancer cell migration: a role for chemokine receptors? Journal article; 2001; Cancer Research Links: IRIS | UCL Discovery | Author's Authors: Scotton CJ,Wilson JL,Milliken D,Stamp G,Balkwill FR click to collapse Developing a collaborative agenda for humanities and social scientific research on laboratory animal science and welfare Journal article; 2016; PLoS ONE Links: IRIS | UCL Discovery | DOI Authors: Davies GF,Greenhough BJ,Hobson-West P,Kirk RGW,Applebee K,Bellingan LC,Berdoy M,Buller H,Cassaday HJ,Davies K,Diefenbacher D,Druglitrø T,Escobar MP,Friese C,Herrmann K,Hinterberger A,Jarrett WJ,Jayne K,Johnson AM,Johnson ER,Konold T,Leach MC,Leonelli S,Lewis DI,Lilley EJ,Longridge ER,McLeod CM,Miele M,Nelson NC,Ormandy EH,Pallett H,Poort L,Pound P,Ramsden E,Roe E,Scalway H,Schrader A,Scotton CJ,Scudamore CL,Smith JA,Whitfield L,Wolfensohn S click to collapse TGF? upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells. Journal article; 2016; Oncotarget Links: IRIS Authors: Smoktunowicz N,Platé M,Stern AO,D'Antongiovanni V,Robinson E,Chudasama V,Caddick S,Scotton CJ,Jarai G,Chambers RC click to collapse Platform Technologies for Directly Reconstructing 3D Living Biomaterials Journal article; 2015; ADVANCED MATERIALS Links: IRIS | UCL Discovery | Author's | DOI Authors: Jayasinghe SN,Auguste J,Scotton CJ click to collapse The anti-fibrotic effect of inhibition of TGF beta-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent gamma-herpesvirus infection Journal article; 2015; DISEASE MODELS & MECHANISMS Links: IRIS | UCL Discovery | Author's | DOI Authors: Smoktunowicz N,Alexander RE,Franklin L,Williams AE,Holman B,Mercer PF,Jarai G,Scotton CJ,Chambers RC click to collapse Hypomethylation Of The Tnxb Gene Contributes To Increased Expression And Deposition Of Tenascin-X In Idiopathic Pulmonary Fibrosis Journal article; 2014; AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Links: IRIS | Author's Authors: Garner IM,Evans IC,Barnes JL,Maher TM,Renzoni EA,Denton CP,Scotton CJ,Abraham DJ,McAnulty RJ click to collapse Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis. Journal article; 2014; Br J Pharmacol Links: IRIS | UCL Discovery | Author's | DOI Authors: Baliga RS,Scotton CJ,Trinder SL,Chambers RC,MacAllister RJ,Hobbs AJ click to collapse Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages. Journal article; 2014; PLoS One Links: IRIS | UCL Discovery | Author's | DOI Authors: Kallis YN,Scotton CJ,Mackinnon AC,Goldin RD,Wright NA,Iredale JP,Chambers RC,Forbes SJ click to collapse Proteinase-activated receptor-1, CCL2, and CCL7 regulate acute neutrophilic lung inflammation. Journal article; 2014; Am J Respir Cell Mol Biol Links: IRIS | UCL Discovery | Author's | DOI Authors: Mercer PF,Williams AE,Scotton CJ,José RJ,Sulikowski M,Moffatt JD,Murray LA,Chambers RC click to collapse Evidence for a functional thymic stromal lymphopoietin signaling axis in fibrotic lung disease. Journal article; 2013; J Immunol Links: IRIS | UCL Discovery | Author's | DOI Authors: Datta A,Alexander R,Sulikowski MG,Nicholson AG,Maher TM,Scotton CJ,Chambers RC click to collapse Ex vivo micro-computed tomography analysis of bleomycin-induced lung fibrosis for preclinical drug evaluation. Journal article; 2013; Eur Respir J Links: IRIS | UCL Discovery | Author's | DOI Authors: Scotton CJ,Hayes B,Alexander R,Datta A,Forty EJ,Mercer PF,Blanchard A,Chambers RC click to collapse Genome-wide analysis identifies multiple genes with altered methylation and expression in IPF and SSc lung fibroblasts Conference ; 2013; INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Links: IRIS | UCL Discovery | Author's Authors: Garner IM,Evans IC,Maher TM,Renzoni EA,Denton CP,Scotton CJ,Abraham DJ,McAnulty RJ click to collapse Hypomethylation of the TNXB gene contributes to increased expression and deposition of tenascin X in idiopathic pulmonary fibrosis Conference ; 2013; INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Links: IRIS | UCL Discovery | Author's Authors: Garner IM,Evans IC,Barnes JL,Maher TM,Renzoni EA,Denton CP,Scotton CJ,Abraham DJ,McAnulty RJ click to collapse Coagulation cascade proteinases in lung injury and fibrosis. Journal article; 2012; Proc Am Thorac Soc Links: IRIS | UCL Discovery | Author's | DOI Authors: Chambers RC,Scotton CJ click to collapse EXOGENOUS MACROPHAGES ARE RETAINED IN MOUSE LUNGS AFTER INJURY AND TARGET THERAPEUTIC TRANSGENES TO THE INJURED LUNG PARENCHYMA Conference ; 2012; THORAX Links: IRIS | UCL Discovery | Author's | DOI Authors: McNulty K,Sage EK,Alexander R,Scotton CJ,Janes SM click to collapse In search of the fibrotic epithelial cell: opportunities for a collaborative network. Journal article; 2012; Thorax Links: IRIS | UCL Discovery | Author's | DOI Authors: Jenkins G,Blanchard A,Borok Z,Bradding P,Ehrhardt C,Fisher A,Hirani N,Johnson S,Königshoff M,Maher TM,Millar A,Parfrey H,Scotton C,Tetley T,Thickett D,Wolters P,ECIPF workshop click to collapse Innate immunity in lung fibrosis: a therapeutic role for surfactant protein D? Journal article; 2012; Am J Respir Crit Care Med Links: IRIS | UCL Discovery | Author's | DOI Authors: Scotton CJ,Chambers RC click to collapse THE EXTRINSIC COAGULATION PATHWAY IS LOCALLY UPREGULATED IN AN EXPERIMENTAL MODEL OF VIRAL EXACERBATION OF PULMONARY FIBROSIS Conference ; 2012; THORAX Links: IRIS | UCL Discovery | Author's | DOI Authors: Smoktunowicz N,Alexander R,Franklin L,Williams AE,Jarai G,Scotton CJ,Mercer PF,Chambers RC click to collapse A breath of fresh air for tissue engineering? Journal article; 2011; MATERIALS TODAY Links: IRIS | UCL Discovery | Author's Authors: Scotton CJ Bio-electrosprayed living composite matrix implanted into mouse models. Journal article; 2011; Macromol Biosci Links: IRIS | UCL Discovery | Author's | DOI Authors: Jayasinghe SN,Warnes G,Scotton CJ click to collapse MACROPHAGES AS VEHICLES FOR DELIVERING CELL THERAPY TO INJURED LUNG Conference ; 2011; THORAX Links: IRIS | UCL Discovery | Author's | DOI Authors: McNulty K,Scotton CJ,Sage EK,Chambers RC,Janes SM click to collapse Novel therapeutic approaches for pulmonary fibrosis. Journal article; 2011; Br J Pharmacol Links: IRIS | UCL Discovery | Author's | DOI Authors: Datta A,Scotton CJ,Chambers RC click to collapse Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes. Journal article; 2011; Part Fibre Toxicol Links: IRIS | UCL Discovery | Author's | DOI Authors: Cho WS,Duffin R,Howie SE,Scotton CJ,Wallace WA,Macnee W,Bradley M,Megson IL,Donaldson K click to collapse