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Portal vein thrombosis associated with protein C deficiency and elevated Factor VIII in hepatosplenic schistosomiasis Journal article; 2016; BLOOD COAGULATION & FIBRINOLYSIS Links: IRIS | Author's | DOI Authors: Calheiros Leite LA,dos Santos Ferreira RDC,Domingues Hatzlhofer BL,Barros Correia MC,Bandeira AP,Owen JS,de Menezes Lima VL,Coutinho Domingues AL,Lopes EP click to collapse Splenectomy Improves Hemostatic and Liver Functions in Hepatosplenic Schistosomiasis Mansoni Journal article; 2015; PLOS ONE Links: IRIS | Author's | DOI Authors: Calheiros Leite LA,Pimenta Filho AA,dos Santos Ferreira RDC,Martins da Fonseca CS,dos Santos BS,Lucena Montenegro SM,de Almeida Lopes EP,Coutinho Domingues AL,Owen JS,de Menezes Lima VL click to collapse Development of therapeutic splice-switching oligonucleotides. Journal article; 2014; Hum Gene Ther Links: IRIS | UCL Discovery | Author's | DOI Authors: Disterer P,Kryczka A,Liu Y,Badi YE,Wong JJ,Owen JS,Khoo B click to collapse Human plasma lipid modulation in schistosomiasis mansoni depends on apolipoprotein E polymorphism. Journal article; 2014; PLoS One Links: IRIS | UCL Discovery | Author's | DOI Authors: Martins da Fonseca CS,Pimenta Filho AA,dos Santos BS,da Silva CA,Domingues AL,Owen JS,Lima VL click to collapse APO-skip splice-switching oligonucleotides to treat familial hypercholesterolemia Conference ; 2013; HUMAN GENE THERAPY Links: IRIS | UCL Discovery | Author's Authors: Disterer P,Simons JP,Owen JS,Khoo B click to collapse Exon Skipping of Hepatic APOB pre-mRNA with Splice-switching Oligonucleotides Reduces LDL Cholesterol In Vivo Journal article; 2013; Molecular Therapy Links: IRIS | UCL Discovery | DOI | Publisher Authors: Disterer P,Al-Shawi R,Ellmerich S,Waddington SN,Owen JS,Simons JP,Khoo B click to collapse Hemostatic Dysfunction Is Increased in Patients with Hepatosplenic Schistosomiasis Mansoni and Advanced Periportal Fibrosis Journal article; 2013; PLOS NEGLECTED TROPICAL DISEASES Links: IRIS | UCL Discovery | Author's | DOI Authors: Calheiros Leite LA,Pimenta Filho AA,Martins da Fonseca CS,dos Santos BS,dos Santos Ferreira RDC,Lucena Montenegro SM,Lopes EP,Coutinho Domingues AL,Owen JS,de Menezes Lima VL click to collapse Oligonucleotide-directed gene-editing technology: mechanisms and future prospects. Journal article; 2012; Expert Opin Biol Ther Links: IRIS | UCL Discovery | Author's | DOI Authors: Papaioannou I,Simons JP,Owen JS click to collapse Oligonucleotide-mediated gene editing is underestimated in cells expressing mutated green fluorescent protein and is positively associated with target protein expression. Journal article; 2012; J Gene Med Links: IRIS | UCL Discovery | Author's | DOI Authors: Disterer P,Papaioannou I,Evans VC,Simons JP,Owen JS click to collapse Spectroscopic photoacoustic imaging of lipid-rich plaques in the human aorta in the 740 to 1400 nm wavelength range. Journal article; 2012; J Biomed Opt Links: IRIS | UCL Discovery | Author's | DOI Authors: Allen TJ,Hall A,Dhillon AP,Owen JS,Beard PC click to collapse Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein. Journal article; 2012; Cardiol Res Pract Links: IRIS | UCL Discovery | Author's | DOI Authors: Papaioannou I,Simons JP,Owen JS click to collapse Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle. Journal article; 2011; Metabolism Links: IRIS | UCL Discovery | Author's | DOI Authors: Evans VC,Graham IR,Athanasopoulos T,Galley DJ,Jackson CL,Simons JP,Dickson G,Owen JS click to collapse Photoacoustic imaging of lipid rich plaques in human aorta Conference ; 2010; PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2010 Links: IRIS | UCL Discovery | Author's | DOI Authors: Allen TJ,Hall A,Dhillon A,Owen JS,Beard PC click to collapse Oligonucleotide-directed gene editing technology: mechanisms and future prospects Journal article; 2009; Expert Opinion on Biological Therapy Links: IRIS | UCL Discovery Authors: Papaioannou I,Owen JS click to collapse Use of internally nuclease-protected single-stranded DNA oligonucleotides and silencing of the mismatch repair protein, MSH2, enhances the replication of corrected cells following gene editing Journal article; 2009; The Journal of Gene Medicine Links: IRIS | UCL Discovery | Author's | DOI Authors: Papaioannou I,Disterer P,Owen JS click to collapse Validation of oligonucleotide-mediated gene editing Journal article; 2009; Gene Therapy Links: IRIS | UCL Discovery | Author's Authors: Disterer P,Simons JP,Owen JS click to collapse Gene therapy for apolipoprotein A-I and HDL ? the ultimate treatment for atherosclerosis? Chapter; 2008; Links: IRIS | UCL Discovery Authors: Disterer P,Osman E,Owen JS click to collapse How does interferon inhibit HCV cell entry? Journal article; 2008; Gut Links: IRIS | UCL Discovery | Author's Authors: Jones M,Owen JS click to collapse How does interferon inhibit HCV cell entry? Journal article; 2008; GUT Links: IRIS | UCL Discovery | Author's | DOI Authors: Jones M,Owen JS click to collapse Human ApoE expression from mouse skeletal muscle by electrotransfer of non-viral DNA (plasmid) and pseudotyped recombinant adeno-associated virus (AAV2/7) Journal article; 2008; Human Gene Therapy Links: IRIS | UCL Discovery | Author's Authors: Evans V,Graham I,Foster H,Foster K,Simons JP,Dickson G,Owen JS click to collapse Human apolipoprotein E expression from mouse skeletal muscle by electrotransfer of nonviral DNA (plasmid) and pseudotyped recombinant adeno-associated virus (AAV2/7). Journal article; 2008; Human Gene Therapy Links: IRIS | UCL Discovery | Author's | DOI Authors: Evans V,Foster H,Graham IR,Foster K,Athanasopoulos T,Simons JP,Dickson G,Owen JS click to collapse Preliminary evaluation of a self-complementary AAV2/8 vector for hepatic gene transfer of human apoE3 to inhibit atherosclerotic lesion development in apoE-deficient mice Journal article; 2008; Atherosclerosis Links: IRIS | UCL Discovery | Author's | DOI Authors: Osman E,Evans V,Graham IR,Athanasopoulos T,McIntosh J,Nathwani AC,Simons JP,Dickson GO,J S click to collapse High and stable genomic sequence modification with oligonucleotide-mediated gene editing Conference ; 2007; HUMAN GENE THERAPY Links: IRIS | UCL Discovery | Author's Authors: Disterer P,Papaioannou I,Simons JP,Owen JS click to collapse Liver-directed gene transfer of atheroprotective human ApoA-I(Milano) Conference ; 2007; HUMAN GENE THERAPY Links: IRIS | UCL Discovery | Author's Authors: Osman E,Graham I,Athanasopoulos T,Nathwani AC,Owen JS click to collapse Scavenger receptor BI and BII expression levels modulate hepatitis C virus infectivity. Journal article; 2007; Journal of Virology Links: IRIS | UCL Discovery | Author's Authors: Grove J,Huby T,Stamataki Z,Vanwolleghem T,Meuleman P,M S,A M,M O,J S L-R,G B,P M,J click to collapse