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Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20) Journal article; 2016; SCIENTIFIC REPORTS Links: IRIS | UCL Discovery | Author's | DOI Authors: Burrows N,Cane G,Robson M,Gaude E,Howat WJ,Szlosarek PW,Pedley RB,Frezza C,Ashcroft M,Maxwell PH click to collapse C3 glomerulonephritis and CFHR5 nephropathy. Journal article; 2013; Nephrol Dial Transplant Links: IRIS | UCL Discovery | Author's | DOI Authors: Gale DP,Maxwell PH click to collapse Epistatic role of the MYH9/APOL1 region on familial hematuria genes. Journal article; 2013; PLoS One Links: IRIS | UCL Discovery | Author's | DOI Authors: Voskarides K,Demosthenous P,Papazachariou L,Arsali M,Athanasiou Y,Zavros M,Stylianou K,Xydakis D,Daphnis E,Gale DP,Maxwell PH,Elia A,Pattaro C,Pierides A,Deltas C click to collapse Incidence of end-stage renal disease in the Turkish-Cypriot population of Northern Cyprus: a population based study. Journal article; 2013; PLoS One Links: IRIS | UCL Discovery | Author's | DOI Authors: Connor TM,Oygar DD,Gale DP,Steenkamp R,Nitsch D,Neild GH,Maxwell PH click to collapse (sic)HIGH INCIDENCE OF END-STAGE RENAL DISEASE IN THE TURKISH-CYPRIOT POPULATION OF NORTHERN CYPRUS: A POPULATION BASED STUDY. Conference ; 2012; NEPHROLOGY DIALYSIS TRANSPLANTATION Links: IRIS | UCL Discovery | Author's Authors: Connor T,Oygar D,Nitsch D,Gale D,Steenkamp R,Neild GH,Maxwell P click to collapse Aspiring to prevent colon cancer Journal article; 2012; NATURE MEDICINE Links: IRIS | UCL Discovery | Author's Authors: Maxwell PH Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. Journal article; 2012; Am J Pathol Links: IRIS | UCL Discovery | Author's | DOI Authors: Mowat FM,Gonzalez F,Luhmann UF,Lange CA,Duran Y,Smith AJ,Maxwell PH,Ali RR,Bainbridge JW click to collapse Epigenetic regulation of HIF-1? in renal cancer cells involves HIF-1?/2? binding to a reverse hypoxia-response element. Journal article; 2012; Oncogene Links: IRIS | UCL Discovery | Author's | DOI Authors: Xu J,Wang B,Xu Y,Sun L,Tian W,Shukla D,Barod R,Grillari J,Grillari-Voglauer R,Maxwell PH,Esteban MA click to collapse Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression. Journal article; 2012; J Clin Invest Links: IRIS | UCL Discovery | Author's | DOI Authors: Yang J,Staples O,Thomas LW,Briston T,Robson M,Poon E,Simões ML,El-Emir E,Buffa FM,Ahmed A,Annear NP,Shukla D,Pedley BR,Maxwell PH,Harris AL,Ashcroft M click to collapse Increasing evidence that genetic variation in complement factor H related 5 (CFHR5) causes disease: a commentary on 'Atypical haemolytic uremic syndrome and genetic aberrations in the complement factor-H-related 5 gene'. Journal article; 2012; J Hum Genet Links: IRIS | UCL Discovery | Author's | DOI Authors: Maxwell PH Next generation sequencing and internal medicine in the NHS - too much information? Conference ; 2012; JOURNAL OF MEDICAL GENETICS Links: IRIS | UCL Discovery | Author's Authors: Maxwell P Renal tubular HIF-2? expression requires VHL inactivation and causes fibrosis and cysts. Journal article; 2012; PLoS One Links: IRIS | UCL Discovery | Author's | DOI Authors: Schietke RE,Hackenbeck T,Tran M,Günther R,Klanke B,Warnecke CL,Knaup KX,Shukla D,Rosenberger C,Koesters R,Bachmann S,Betz P,Schley G,Schödel J,Willam C,Winkler T,Amann K,Eckardt KU,Maxwell P,Wiesener MS click to collapse The ERA-EDTA Working Group on inherited kidney disorders. Journal article; 2012; Nephrol Dial Transplant Links: IRIS | UCL Discovery | Author's | DOI Authors: Devuyst O,Antignac C,Bindels RJ,Chauveau D,Emma F,Gansevoort R,Maxwell PH,Ong AC,Remuzzi G,Ronco P,Schaefer F click to collapse Tumor strengths and frailties: Aspiring to prevent colon cancer. Journal article; 2012; Nat Med Links: IRIS | UCL Discovery | Author's | DOI Authors: Maxwell PH Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Journal article; 2012; Development Links: IRIS | UCL Discovery | Author's | DOI Authors: Lange CA,Luhmann UF,Mowat FM,Georgiadis A,West EL,Abrahams S,Sayed H,Powner MB,Fruttiger M,Smith AJ,Sowden JC,Maxwell PH,Ali RR,Bainbridge JW click to collapse What happens to clinical training fellows? A retrospective study of the 20 years outcome of a Medical Research Council UK cohort. Journal article; 2012; BMJ Open Links: IRIS | UCL Discovery | Author's | DOI Authors: Stewart PM,Bryan S,Dukes P,van Oudheusden HL,Walker R,Maxwell PH click to collapse Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation. Journal article; 2011; FASEB J Links: IRIS | UCL Discovery | Author's | DOI Authors: Formenti F,Beer PA,Croft QP,Dorrington KL,Gale DP,Lappin TR,Lucas GS,Maher ER,Maxwell PH,McMullin MF,O'Connor DF,Percy MJ,Pugh CW,Ratcliffe PJ,Smith TG,Talbot NP,Robbins PA click to collapse Copy number profiling in von Hippel-Lindau disease renal cell carcinoma. Journal article; 2011; Genes Chromosomes Cancer Links: IRIS | UCL Discovery | Author's | DOI Authors: Shuib S,Wei W,Sur H,Morris MR,McMullan D,Rattenberry E,Meyer E,Maxwell PH,Kishida T,Yao M,Latif F,Maher ER click to collapse Developmentally arrested structures preceding cerebellar tumors in von Hippel-Lindau disease. Journal article; 2011; Mod Pathol Links: IRIS | UCL Discovery | Author's | DOI Authors: Shively SB,Falke EA,Li J,Tran MG,Thompson ER,Maxwell PH,Roessler E,Oldfield EH,Lonser RR,Vortmeyer AO click to collapse Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms. Journal article; 2011; Lab Invest Links: IRIS | UCL Discovery | Author's | DOI Authors: Marchbank T,Mahmood A,Harten S,Maxwell PH,Playford RJ click to collapse Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension. Journal article; 2011; Blood Links: IRIS | UCL Discovery | Author's | DOI Authors: Bond J,Gale DP,Connor T,Adams S,de Boer J,Gascoyne DM,Williams O,Maxwell PH,Ancliff PJ click to collapse Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1?-mediated apoptosis. Journal article; 2011; Br J Cancer Links: IRIS | UCL Discovery | Author's | DOI Authors: Khan MN,Bhattacharyya T,Andrikopoulos P,Esteban MA,Barod R,Connor T,Ashcroft M,Maxwell PH,Kiriakidis S click to collapse Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees. Journal article; 2011; Clin J Am Soc Nephrol Links: IRIS | UCL Discovery | Author's | DOI Authors: Athanasiou Y,Voskarides K,Gale DP,Damianou L,Patsias C,Zavros M,Maxwell PH,Cook HT,Demosthenous P,Hadjisavvas A,Kyriacou K,Zouvani I,Pierides A,Deltas C click to collapse Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Journal article; 2011; Nature Links: IRIS | UCL Discovery | Author's | DOI Authors: International Consortium for Blood Pressure Genome-Wide Association Studies ,Ehret GB,Munroe PB,Rice KM,Bochud M,Johnson AD,Chasman DI,Smith AV,Tobin MD,Verwoert GC,Hwang SJ,Pihur V,Vollenweider P,O'Reilly PF,Amin N,Bragg-Gresham JL,Teumer A,Glazer NL,Launer L,Zhao JH,Aulchenko Y,Heath S,Sõber S,Parsa A,Luan J,Arora P,Dehghan A,Zhang F,Lucas G,Hicks AA,Jackson AU,Peden JF,Tanaka T,Wild SH,Rudan I,Igl W,Milaneschi Y,Parker AN,Fava C,Chambers JC,Fox ER,Kumari M,Go MJ,van der Harst P,Kao WH,Sjögren M,Vinay DG,Alexander M,Tabara Y,Shaw-Hawkins S,Whincup PH,Liu Y,Shi G,Kuusisto J,Tayo B,Seielstad M,Sim X,Nguyen KD,Lehtimäki T,Matullo G,Wu Y,Gaunt TR,Onland-Moret NC,Cooper MN,Platou CG,Org E,Hardy R,Dahgam S,Palmen J,Vitart V,Braund PS,Kuznetsova T,Uiterwaal CS,Adeyemo A,Palmas W,Campbell H,Ludwig B,Tomaszewski M,Tzoulaki I,Palmer ND,CARDIoGRAM consortium ,CKDGen Consortium ,KidneyGen Consortium ,EchoGen consortium ,CHARGE-HF consortium ,Aspelund T,Garcia M,Chang YP,O'Connell JR,Steinle NI,Grobbee DE,Arking DE,Kardia SL,Morrison AC,Hernandez D,Najjar S,McArdle WL,Hadley D,Brown MJ,Connell JM,Hingorani AD,Day IN,Lawlor DA,Beilby JP,Lawrence RW,Clarke R,Hopewell JC,Ongen H,Dreisbach AW,Li Y,Young JH,Bis JC,Kähönen M,Viikari J,Adair LS,Lee NR,Chen MH,Olden M,Pattaro C,Bolton JA,Köttgen A,Bergmann S,Mooser V,Chaturvedi N,Frayling TM,Islam M,Jafar TH,Erdmann J,Kulkarni SR,Bornstein SR,Grässler J,Groop L,Voight BF,Kettunen J,Howard P,Taylor A,Guarrera S,Ricceri F,Emilsson V,Plump A,Barroso I,Khaw KT,Weder AB,Hunt SC,Sun YV,Bergman RN,Collins FS,Bonnycastle LL,Scott LJ,Stringham HM,Peltonen L,Perola M,Vartiainen E,Brand SM,Staessen JA,Wang TJ,Burton PR,Soler Artigas M,Dong Y,Snieder H,Wang X,Zhu H,Lohman KK,Rudock ME,Heckbert SR,Smith NL,Wiggins KL,Doumatey A,Shriner D,Veldre G,Viigimaa M,Kinra S,Prabhakaran D,Tripathy V,Langefeld CD,Rosengren A,Thelle DS,Corsi AM,Singleton A,Forrester T,Hilton G,McKenzie CA,Salako T,Iwai N,Kita Y,Ogihara T,Ohkubo T,Okamura T,Ueshima H,Umemura S,Eyheramendy S,Meitinger T,Wichmann HE,Cho YS,Kim HL,Lee JY,Scott J,Sehmi JS,Zhang W,Hedblad B,Nilsson P,Smith GD,Wong A,Narisu N,Stan?áková A,Raffel LJ,Yao J,Kathiresan S,O'Donnell CJ,Schwartz SM,Ikram MA,Longstreth WT,Mosley TH,Seshadri S,Shrine NR,Wain LV,Morken MA,Swift AJ,Laitinen J,Prokopenko I,Zitting P,Cooper JA,Humphries SE,Danesh J,Rasheed A,Goel A,Hamsten A,Watkins H,Bakker SJ,van Gilst WH,Janipalli CS,Mani KR,Yajnik CS,Hofman A,Mattace-Raso FU,Oostra BA,Demirkan A,Isaacs A,Rivadeneira F,Lakatta EG,Orru M,Scuteri A,Ala-Korpela M,Kangas AJ,Lyytikäinen LP,Soininen P,Tukiainen T,Würtz P,Ong RT,Dörr M,Kroemer HK,Völker U,Völzke H,Galan P,Hercberg S,Lathrop M,Zelenika D,Deloukas P,Mangino M,Spector TD,Zhai G,Meschia JF,Nalls MA,Sharma P,Terzic J,Kumar MV,Denniff M,Zukowska-Szczechowska E,Wagenknecht LE,Fowkes FG,Charchar FJ,Schwarz PE,Hayward C,Guo X,Rotimi C,Bots ML,Brand E,Samani NJ,Polasek O,Talmud PJ,Nyberg F,Kuh D,Laan M,Hveem K,Palmer LJ,van der Schouw YT,Casas JP,Mohlke KL,Vineis P,Raitakari O,Ganesh SK,Wong TY,Tai ES,Cooper RS,Laakso M,Rao DC,Harris TB,Morris RW,Dominiczak AF,Kivimaki M,Marmot MG,Miki T,Saleheen D,Chandak GR,Coresh J,Navis G,Salomaa V,Han BG,Zhu X,Kooner JS,Melander O,Ridker PM,Bandinelli S,Gyllensten UB,Wright AF,Wilson JF,Ferrucci L,Farrall M,Tuomilehto J,Pramstaller PP,Elosua R,Soranzo N,Sijbrands EJ,Altshuler D,Loos RJ,Shuldiner AR,Gieger C,Meneton P,Uitterlinden AG,Wareham NJ,Gudnason V,Rotter JI,Rettig R,Uda M,Strachan DP,Witteman JC,Harti click to collapse Hypoxia and Upregulation of Hypoxia-Inducible Factor 1 alpha Stimulate Venous Thrombus Recanalization (vol 30, pg 2443, 2010) Journal article; 2011; ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Links: IRIS | UCL Discovery | Author's | DOI Authors: Evans ,Maxwell PH click to collapse