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Weitsman, G., Mitchell, N. J., Evans, R., Cheung, A., Kalber, T. L., Bofinger, R., . . . Ng, T. (2017). Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor. Oncogene. doi:10.1038/onc.2016.522
Higson, S., Subrizi, F., Sheppard, T. D., & Hailes, H. C. (2016). Chemical cascades in water for the synthesis of functionalized aromatics from furfurals. GREEN CHEMISTRY, 18 (7), 1855-1858. doi:10.1039/c5gc02935j
Kudsiova, L., Welser, K., Campbell, F., Mohammadi, A., Dawson, N., Cui, L., . . . Tabor, A. B. (2016). Delivery of siRNA using ternary complexes containing branched cationic peptides: the role of peptide sequence, branching and targeting. MOLECULAR BIOSYSTEMS, 12 (3), 934-951. doi:10.1039/c5mb00754b
Jeffries, J. W. E., Dawson, N., Orengo, C., Moody, T. S., Quinn, D. J., Hailes, H. C., & Ward, J. M. (2016). Metagenome Mining: A Sequence Directed Strategy for the Retrieval of Enzymes for Biocatalysis. ChemistrySelect, 1 (10), 2217-2220. doi:10.1002/slct.201600515
McLaughlin, C., Assmann, M., Parkes, M. A., Woodhouse, J. L., Lewin, R., Hailes, H. C., . . . Fielding, H. H. (2016). ortho and para chromophores of green fluorescent protein: controlling electron emission and internal conversion. Chem. Sci.. doi:10.1039/C6SC03833F
Hayes, T., Hu, Y., Sanchez-Vazquez, S. A., Hailes, H. C., Aliev, A. E., & Evans, J. R. G. (2016). Strategies for synthesis of epoxy resins from oleic acid derived from food wastes. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 54 (19), 3159-3170. doi:10.1002/pola.28203
Affaticati, P. E., Dai, S. -. B., Payongsri, P., Hailes, H. C., Tittmann, K., & Dalby, P. A. (2016). Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes. SCIENTIFIC REPORTS, 6, ARTN 35716. doi:10.1038/srep35716
Subrizi, F., Cardenas-Fernandez, M., Lye, G. J., Ward, J. M., Dalby, P. A., Sheppard, T. D., & Hailes, H. C. (2016). Transketolase catalysed upgrading of L-arabinose: the one-step stereoselective synthesis of L-gluco-heptulose. GREEN CHEMISTRY, 18 (10), 3158-3165. doi:10.1039/c5gc02660a
Lichman, B. R., Gershater, M. C., Lamming, E. D., Pesnot, T., Sula, A., Keep, N. H., . . . Ward, J. M. (2015). 'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile. FEBS JOURNAL, 282 (6), 1137-1151. doi:10.1111/febs.13208
Baud, D., Ladkau, N., Moody, T. S., Ward, J. M., & Hailes, H. C. (2015). A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase. CHEMICAL COMMUNICATIONS, 51 (97), 17225-17228. doi:10.1039/c5cc06817g
Rios-Solis, L., Morris, P., Grant, C., Odeleye, A. O. O., Hailes, H. C., Ward, J. M., . . . Lye, G. J. (2015). Modelling and optimisation of the one-pot, multi-enzymatic synthesis of chiral amino-alcohols based on microscale kinetic parameter determination. CHEMICAL ENGINEERING SCIENCE, 122, 360-372. doi:10.1016/j.ces.2014.09.046
Villegas-Torres, M. F., Martinez-Torres, R. J., Cazares-Koerner, A., Hailes, H., Baganz, F., & Ward, J. (2015). Multi-step biocatalytic strategies for chiral amino alcohol synthesis. ENZYME AND MICROBIAL TECHNOLOGY, 81, 23-30. doi:10.1016/j.enzmictec.2015.07.003
Richter, N., Simon, R. C., Lechner, H., Kroutil, W., Ward, J. M., & Hailes, H. C. (2015). omega-Transaminases for the amination of functionalised cyclic ketones. ORGANIC & BIOMOLECULAR CHEMISTRY, 13 (33), 8843-8851. doi:10.1039/c5ob01204j
Lichman, B. R., Lamming, E. D., Pesnot, T., Smith, J. M., Hailes, H. C., & Ward, J. M. (2015). One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine. GREEN CHEMISTRY, 17 (2), 852-855. doi:10.1039/c4gc02325k
Rowland, T., Hailes, H. C., & Evans, J. R. G. (2015). Sea salt as a potential ocean mirror material. RSC ADVANCES, 5 (49), 38926-38930. doi:10.1039/c5ra03469h
Payongsri, P., Steadman, D., Hailes, H. C., & Dalby, P. A. (2015). Second generation engineering of transketolase for polar aromatic aldehyde substrates. ENZYME AND MICROBIAL TECHNOLOGY, 71, 45-52. doi:10.1016/j.enzmictec.2015.01.008
Deszcz, D., Affaticati, P., Ladkau, N., Gegel, A., Ward, J. M., Hailes, H. C., & Dalby, P. A. (2015). Single active-site mutants are sufficient to enhance serine:pyruvate -transaminase activity in an -transaminase. FEBS JOURNAL, 282 (13), 2512-2526. doi:10.1111/febs.13293
Foster, R. W., Tame, C. J., Bucar, D. -. K., Hailes, H. C., & Sheppard, T. D. (2015). Sustainable Synthesis of Chiral Tetrahydrofurans through the Selective Dehydration of Pentoses. CHEMISTRY-A EUROPEAN JOURNAL, 21 (45), 15947-15950. doi:10.1002/chem.201503510
Lamming, E. D. (2015). Synthesis of N-heterocycles as anti-asthma drugs and compounds with antimycobacterial properties (Doctoral dissertation). UCL (University College London).
Guzman, J. D., Pesnot, T., Barrera, D. A., Davies, H. M., McMahon, E., Evangelopoulos, D., . . . Bhakta, S. (2015). Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70 (6), 1691-1703. doi:10.1093/jac/dkv010
Mooney, C. R. S., Parkes, M. A., Zhang, L., Hailes, H. C., Simperler, A., Bearpark, M. J., & Fielding, H. H. (2014). Competition between photodetachment and autodetachment of the 21 ππ* state of the green fluorescent protein chromophore anion. Journal of Chemical Physics, 140 (20). doi:10.1063/1.4874643
Lamming, E. D., Hailes, H. C., Bhakta, S., Redmond, J. M., & Needham, D. (2014). Design, synthesis, and biological evaluation of alkaloids as potential antituberculosis drugs. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 247. AMER CHEMICAL SOC.
Sehl, T., Hailes, H. C., Ward, J. M., Menyes, U., Pohl, M., & Rother, D. (2014). Efficient 2-step biocatalytic strategies for the synthesis of all nor(pseudo) ephedrine isomers. GREEN CHEMISTRY, 16 (6), 3341-3348. doi:10.1039/c4gc00100a
Pennell, M. N., Foster, R. W., Turner, P. G., Hailes, H. C., Tame, C. J., & Sheppard, T. D. (2014). Gold catalysed synthesis of 3-alkoxyfurans at room temperature. Chem Commun (Camb), 50 (11), 1302-1304. doi:10.1039/c3cc48290a
Aziz, A., Hailes, H. C., Ward, J. M., & Evans, J. R. G. (2014). Long-term stabilization of reflective foams in sea water. RSC Adv., 4 (95), 53028-53036. doi:10.1039/C4RA08714C