个人简介
BSc in Chemistry, Nanjing University, 1992
MSc in Chemistry, Nanjing University, 1997
PhD in Chemistry, Huddersfield University, 2003
近期论文
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Glycomimetic affinity-enrichment proteomics identifies partners for a clinically-utilized iminosugar Journal article ; 2013 ; CHEMICAL SCIENCE links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Cruz IN,Barry CS,Kramer HB,Chuang CC,Lloyd S,van der Spoel AC,Platt FM,Yang M,Davis BG
Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation Journal article ; 2013 ; Oncogene links: IRIS ; UCL Discovery authors [click to collapse] : Brown L,Waseem A,Cruz IN,Szary J,Gunic E,Mannan T,Unadkat M,Yang M,Valderrama F,OToole EA,Wan H
Functional characterization of heat shock protein 90 targeted compounds. Journal article ; 2013 ; Anal Biochem ; United States links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Cruz IN,Zhang Y,de la Fuente M,Schatzlein A,Yang M
Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism Conference ; 2011 ; ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY links: IRIS ; UCL Discovery ; author's authors [click to collapse] : Guimaraes AMR,Fuente M,Stapleton P,Ji X,Oliyide AO,Osbourn A,Pan Y,Bowles DJ,Davis BG,Schatzlein A,Yang M
Structural dissection and high throughput screening of mannosylglycerate synthase Journal article ; 2005 ; Nature Structural & Molecular Biology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Flint J,Taylor E,Yang M,Bolam DN,Tailford L,Martinez-Fleites C,Dodson E,Davis BG,Gilbert HJ,Davies GJ
Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency. Journal article ; 2005 ; Journal of the American Chemical Society links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Yang M,Proctor MR,Bolam DN,Errey JC,Field RA,Gilbert HJ,Davis BG
High throughput mass spectrometry monitoring for multi-substrate enzymes: determining the kinetic parameters and catalytic activities of known and novel glycosyltransferases Journal article ; 2005 ; ChemBioChem links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Yang M,Brazier M,Edwards R,Davis BG
Structure and activity of a flavonoid 3-O-glucosyltransferase reveals the basis for plant natural product modification Journal article ; 2006 ; EMBO Journal links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Offen W,Martinez-Fleites C,Yang M,Eng KL,Davis BG,Davies GJ
Glycosylation of macrolide antibiotics Patent ; 2006 links: IRIS ; UCL Discovery authors [click to collapse] : Davis BG,Gilbert HJ,Yang M,Proctor MR,Bolam DN
The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity. Journal article ; 2007 ; Proceedings of the National Academy of Sciences of the USA links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Bolam DN,Roberts S,Proctor MR,Turkenburg JP,Dodson EJ,Martinez-Fleites C,Yang M,Davis BG,Davies GJ,Gilbert HJ
A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides (Communication) Journal article ; 2007 ; Angewandte Chemie International Edition links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Yang M,Davies GJ,Davis BG
Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays Journal article ; 2009 ; Lab on a Chip links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Huebner A,Bratton D,Whyte G,Yang M,deMello AJ,Abell C,Hollfelder F
Substrate and metal ion promiscuity in mannosylglycerate synthase. Journal article ; 2011 ; Journal of Biological Chemistry links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Nielsen MM,Suits MDL,Yang M,Barry CS,Martinez-Fleites C,Tailford LE,Flint JE,Dumontet C,Davis BG,Gilbert HJ,Davies GJ
High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. Journal article ; 2011 ; Chemical Communications links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Patel SM,Fuente MDL,Ke S,Guimar�es AMR,Oliyide AO,Ji X,Stapleton PD,Osbourn A,Pan Y,Bowles DJ,Davis BG,Schatzlein AG,Yang M
Abstract: Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism Journal article ; 2011 ; Abstract of Papers of the American Chemical Society links: IRIS ; UCL Discovery authors [click to collapse] : Guimaraes AMR,Fuente MDL,Stapleton PD,Ji X,Oliyide AO,Osbourn A,Pandit S,Bowles DJ,Davis BG,Schatzlein AG,Yang M
Metabolomic profiling of liquid Echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4). Journal article ; 2010 ; Planta Medica links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Modarai M,Yang M,Suter A,Kortenkamp A,Heinrich M
Proteomics analysis of ovarian cancer cell lines and tissues reveals drug resistance-associated proteins Journal article ; 2017 ; Cancer Genomics and Proteomics links: IRIS ; doi authors [click to collapse] : Cruz IN,Coley HM,Kramer HB,Madhuri TK,Safuwan NAM,Angelino AR,Yang M
Synthesis and characterization of photoaffinity labelling reagents towards the Hsp90 C-terminal domain. Journal article ; 2016 ; Org Biomol Chem ; England links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Simon B,Huang X,Ju H,Sun G,Yang M
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery. Journal article ; 2016 ; Nat Commun ; England links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Ren K,Liu Y,Wu J,Zhang Y,Zhu J,Yang M,Ju H
A Hexa-Herbal TCM decoction used to treat skin inflammation: an LC-MS-based phytochemical analysis Journal article ; 2016 ; Planta Medica: natural products and medicinal plant research ; Georg Thieme Verlag links: IRIS ; UCL Discovery authors [click to collapse] : Heinrich M,Chang JB,Lane M,Yang M
Liberation of Protein-Specific Glycosylation Information for Glycan Analysis by Exonuclease III-Aided Recycling Hybridization Journal article ; 2016 ; ANALYTICAL CHEMISTRY ; AMER CHEMICAL SOC links: IRIS ; doi ; author's authors [click to collapse] : Chen Y,Ding L,Song W,Yang M,Ju H
Protein-specific Raman imaging of glycosylation on single cells with zone-controllable SERS effect Journal article ; 2016 ; CHEMICAL SCIENCE ; ROYAL SOC CHEMISTRY links: IRIS ; doi ; author's authors [click to collapse] : Chen Y,Ding L,Song W,Yang M,Ju H
Terminal PEGylated DNA-Gold Nanoparticle Conjugates Offering High Resistance to Nuclease Degradation and Efficient Intracellular Delivery of DNA Binding Agents Journal article ; 2015 ; ACS APPLIED MATERIALS & INTERFACES ; AMER CHEMICAL SOC links: IRIS ; doi ; author's authors [click to collapse] : Song L,Guo Y,Roebuck D,Chen C,Yang M,Yang Z,Sreedharan S,Glover C,Thomas JA,Liu D,Guo S,Chen R,Zhout D
Micro-competition system for Raman quantification of multiple glycans on intact cell surface Journal article ; 2015 ; CHEMICAL SCIENCE ; ROYAL SOC CHEMISTRY links: IRIS ; doi ; author's authors [click to collapse] : Chen Y,Ding L,Xu J,Song W,Yang M,Hu J,Ju H
Noninvasive imaging of sialyltransferase activity in living cells by chemoselective recognition Journal article ; 2015 ; SCIENTIFIC REPORTS ; NATURE PUBLISHING GROUP links: IRIS ; doi ; author's authors [click to collapse] : Bao L,Ding L,Yang M,Ju H