个人简介
BPharm (Hons), 1st Class, King’s College London, 1994
PhD (Pharmacology), King’s College London, 1999
研究领域
Non-anticoagulant effects of glycosaminoglycans
Physiological role of endogenous heparin
Role of acetylcholine and its receptors in endothelial cell biology
Novel inhibitors of VEGF
近期论文
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PEGylation and its impact on the design of new protein-based medicines. Journal article ; 2014 ; Future Med Chem ; England links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Ginn C,Khalili H,Lever R,Brocchini S
Overcoming the skin barrier: Enhancement of topical delivery of hexamidine diisethionate Conference ; 2014 ; JOURNAL OF INVESTIGATIVE DERMATOLOGY links: IRIS ; UCL Discovery ; author's authors [click to collapse] : Parisi N,Matts PJ,Lever R,Hadgraft J,Lane ME
Heparanase induces inflammatory cell recruitment in vivo by promoting adhesion to vascular endothelium. Journal article ; 2014 ; Am J Physiol Cell Physiol ; United States links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Lever R,Rose MJ,McKenzie EA,Page CP
Fab-PEG-Fab as a potential antibody mimetic. Journal article ; 2013 ; Bioconjug Chem ; United States links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Khalili H,Godwin A,Choi JW,Lever R,Khaw PT,Brocchini S
exendin-4 reverses biochemical and behavioural deficits in a pre-motor rodent model of Parkinson's disease with combined noradrenergic and serotonergic lesions (Retraction of vol 46, pg 183, 2012) Journal article ; 2013 ; NEUROPEPTIDES links: IRIS ; doi ; author's authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton PS
Retraction notice to exendin-4 reverses biochemical and behavioural deficits in a pre-motor rodent model of parkinson's disease with combined noradrenergic and serotonergic lesions [YNPEP 46 (2012) 183-193] Journal article ; 2013 ; Neuropeptides links: IRIS ; UCL Discovery ; doi authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton PS
Exendin-4 reverses biochemical and behavioral deficits in a pre-motor rodent model of Parkinson's disease with combined noradrenergic and serotonergic lesions Journal article ; 2012 ; Neuropeptides links: IRIS ; UCL Discovery ; doi authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton PS
Comparative binding of disulfide-bridged PEG-Fabs Journal article ; 2012 ; Bioconjug Chem links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Brocchini S,Khalili H,Godwin A,Choi JW,Lever R
The CRF-like peptide urocortin produces a long-lasting recovery in rats made hemiparkinsonian by 6-hydroxydopamine or lipopolysaccharide Journal article ; 2008 ; Journal of the Neurological Sciences links: IRIS ; UCL Discovery ; publisher authors [click to collapse] : Abuirmeileh A,Harkavyi A,Kingsbury AE,Lever R,Whitton PS
Exendin-4 reverts behavioural and neurochemical dysfunction in a pre-motor rodent model of Parkinson's disease with noradrenergic deficit. Journal article ; 2012 ; Br J Pharmacol ; England links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton P
Activation of corticotropin-releasing factor receptor-2 causes bronchorelaxation and inhibits pulmonary inflammation in mice Journal article ; 2006 ; FASEB Journal links: IRIS ; UCL Discovery ; doi authors [click to collapse] : Moffatt JD,Lever R,Page CP
The effects of heparin and related molecules upon the adhesion of human polymorphonuclear leucocytes to vascular endotheliumin vitro Journal article ; 2000 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Hoult JRS,Page CP
HIT dynamics are Fab Journal article ; 2000 ; Trends in Pharmacological Sciences links: IRIS ; UCL Discovery ; doi ; publisher authors : Lever R
The effects of heparin on the adhesion of human peripheral blood mononuclear cells to human stimulated umbilical vein endothelial cells Journal article ; 2001 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Smailbegovic A,Lever R,Page CP
Role of glycosaminoglycans in inflammation Journal article ; 2001 ; InflammoPharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Smailbegovic A,Page CP
Glycosaminoglycans, Airways Inflammation and Bronchial Hyperresponsiveness Journal article ; 2001 ; Pulmonary Pharmacology & Therapeutics links: IRIS ; UCL Discovery ; doi ; publisher authors : Lever R,Page CP
Novel drug development opportunities for Heparin Journal article ; 2002 ; Nature Reviews. Drug discovery links: IRIS ; UCL Discovery ; doi ; publisher authors : Lever R,Page CP
Platelets are essential for leukocyte recruitment in allergic inflammation Journal article ; 2003 ; Journal of Allergy and Clinical Immunology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Pitchford S,Yano H,Lever R,Riffovasquez Y,Ciferri S,Rose M,Gianni S,Momi S,Spina D,OConnor B
Effects of heparin and related molecules upon neutrophil aggregation and elastase releasein vitro Journal article ; 2003 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Brown RA,Lever R,Jones NA,Page CP
Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system. Journal article ; 2004 ; Journal of Immunology links: IRIS ; UCL Discovery authors [click to collapse] : Johnson Z,Kosco-Vilbois MH,Herren S,Cirillo R,Muzio V,Zaratin P,Carbonatto M,Mack M,Smailbegovic A,Rose M,Lever R,Page CP,Wells TNC,Proudfoot AEI
Effects of inhaled thrombin receptor agonists in mice Journal article ; 2004 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Moffatt JD,Lever R,Page CP
Anti-adhesive glycoproteins in echinoderm mucus secretions Journal article ; 2004 ; Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Bavington CD,Lever R,Mulloy B,Grundy MM,Page CP,Richardson NV,McKenzie JD
Activation of corticotropin-releasing factor receptor-2 causes bronchorelaxation and inhibits pulmonary inflammation in mice Journal article ; 2006 ; FASEB Journal links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Moffatt JD,Lever R,Page CP
Size-fractionated heparins have differential effects on human neutrophil functionin vitro Journal article ; 2007 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Lo WT,Faraidoun M,Amin V,Brown RA,Gallagher J,Page CP
Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses Journal article ; 2007 ; Clinical & Experimental Allergy links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Hefni A,Moffatt JD,Paul W,Page CP