个人简介
He studied Chemistry at the University of Bologna – Alma Mater Studiorum (Italy), where he graduated in 1999. He received his PhD in Chemistry in 2003 at Bologna University working in the area of asymmetric catalysis, under the direction of Professor Achille Umani-Ronchi and the supervision of Professor Pier Giorgio Cozzi. In 2002, he spent a period in Denmark working with Professor Karl Anker Jørgensen at the “Center for Catalysis”, Århus University, where his studies centered on asymmetric organocatalysis. In 2003, Paolo worked as a postdoctoral associate with Professor Giuseppe Bartoli, at the Industrial Chemistry Faculty of the Bologna University.
In October 2007, he took a permanent position as an Assistant Professor at Bologna University. In September 2009, Paolo joined the Institute of Chemical Research of Catalonia (ICIQ) in Tarragona as an ICREA (Catalan Institution of Research and Advanced Studies) Professor and ICIQ Group Leader.
Paolo has received the “G. Ciamician” Medal, awarded by the Italian Chemical Society (2007), a JSPS Fellowship under the FY2013 Program for Research in Japan, the 2016 Prize for Scientific Excellence from the Royal Spanish Chemical Society (RSEQ), and the 2019 “G. Modena” Medal from the Italian Chemical Society. He was also nominated Liebig Lecturer 2008 by the Organic Division of the German Chemical Society.
He was featured in the “Author Profile section” of Angewandte Chemie (ACIE 2009, 48, 3389). From 2019, Paolo is an Associate Editor of Chemical Science, the flag-ship journal of the Royal Society of Chemistry (RSC).
In 2011, Paolo has been awarded an ERC Starting Grant to carry out the 5-year project “ORGA-NAUT: Exploring Chemical Reactivity with Organocatalysis”, while in 2016 he has been awarded an ERC Consolidator Grant to carry out the 5-year project “CATA-LUX: Light-Driven Asymmetric Organocatalysis”, both funded by the European Research Council.
The following list summarises the most important steps of his educational and professional career:
MSc in Chemistry University of Bologna (Italy) 1993-1999
PhD in Chemical Sciences University of Bologna 2000-2003
Research Period at Centre for Catalysis University of Århus (DK) 2002
Postdoctoral Fellow in Chemistry University of Bologna 2003-2006
Assistant Professor University of Bologna 2007-2009
Research Professor & Group Leader ICIQ – Tarragona (Spain) Sept. 2009-present
Main Professional Experience
September 2009 PM moved to the Institute of Chemical Research of Catalonia (ICIQ) in Tarragona as an ICREA (Catalan Institution of Research and Advanced Studies) Professor and ICIQ Senior Group Leader.
October 2007 Assistant Professor (Ricercatore) at Bologna University – Alma Mater Studiorum Bologna (Italy) - Dept. of Organic Chemistry, Industrial Chemistry Faculty
研究领域
His current scientific interests lie on the discovery and mechanistic elucidation of new asymmetric
organocatalytic and photochemical processes that address unsolved problems in synthetic methodology. The
final aim is to develop environmentally friendly and innovative catalytic methods that will find widespread use
in organic synthesis.
近期论文
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PM has an h-factor of 60 and has attracted a total of 9950 citations for the period 1999-2019 (source: ISIWeb of Science as of October 1, 2019).
Photochemical Asymmetric Nickel‐Catalyzed Acyl Cross‐Coupling Euegenio Gandolfo, Xinjun Tang, Sudipta Raha Roy, and Paolo Melchiorre Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201910168
Photochemical C‐H Hydroxyalkylation of Quinolines and Isoquinolines Bartosz Bieszczad, Luca A. Perego, and Paolo Melchiorre Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201910641
Photo‐Organocatalytic Enantioselective Radical Cascade Enabled by Single‐Electron Transfer Activation of Allenes Luca A. Perego, Pablo Bonilla, and Paolo Melchiorre Adv. Synth. Catal. 2019, DOI: 10.1002/adsc.201900973 (EN Jacobsen special issue)
A Redox Active Nickel Complex that Acts as an Electron Mediator in Photochemical Giese Reactions Thomas van Leeuwen, Luca Buzzetti, Luca A. Perego and Melchiorre Angew. Chem. Int. Ed. 2019, 58, 4953–4957 (open access [Link])
Photochemical Organocatalytic Borylation of Alkyl Chlorides, Bromides, and Sulfonates Daniele Mazzarella, Giandomenico Magagnano, Bertrand Schweitzer-Chaput and Paolo Melchiorre ACS Catal. 2019, 9, 5876–5880 (open access [Link])
A visible-light mediated three-component radical process using dithiocarbamate anion catalysis Sara Cuadros, Matthew A. Horwitz, Bertrand Schweitzer-Chaput and Paolo Melchiorre Chem. Sci. 2019, 10, 5484–5488 (open access [Link])
Photochemical generation of radicals from alkyl electrophiles using a nucleophilic organic Catalyst Bertrand Schweitzer-Chaput, Matthew A. Horwitz, Eduardo de Pedro Beato, and Paolo Melchiorre Nature Chem. 2019, 11, 129–135. [Link]
Stereocontrolled Synthesis of 1,4‐Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals Giulio Goti, Bartosz Bieszczad, Alberto Vega-Peñaloza, and Paolo Melchiorre Angew. Chem. Int. Ed. 2019, 58, 1213–1217 (open access [Link])
Mechanistic Studies in Photocatalysis Luca Buzzetti, Giacomo E. M. Crisenza, and Paolo Melchiorre Angew. Chem. Int. Ed. 2019, 58, 3730–3747 (review - open access, [Link])
Enhancing the potential of enantioselective organocatalysis with light Mattia Silvi, and Paolo Melchiorre Nature 2018, 554, 41–49 (review [Link])
Enantioselective radical conjugate additions driven by a photoactive intramolecular iminiumion-based EDA complex Zhong-Yan Cao, Tamal Ghosh, and Paolo Melchiorre Nat. Commun. 2018, 9, 3274 (open access [Link])
Organocatalytic Strategies to Stereoselectively Trap Photochemically Generated Hydroxy-oquinodimethanes Sara Cuadros and Paolo Melchiorre Eur. J. Org. Chem. 2018, 2884–2891 (review)
Asymmetric photocatalytic C–H functionalization of toluene and derivatives Daniele Mazzarella, Giacomo E.M. Crisenza, and Paolo Melchiorre J. Am. Chem. Soc. 2018, 140, 8439–8443 (open access [Link])
Photo‐Organocatalytic Enantioselective Radical Cascade Reactions of Unactivated Olefins Pablo Bonilla, Yannick P. Rey, Catherine Holden, and Paolo Melchiorre Angew. Chem. Int. Ed. 2018, 57, 12819–12823 (open access [Link])
Enantioselective Photochemical Organo-Cascade Catalysis Łukasz Woźniak, Giandomenico Magagnano, and Paolo Melchiorre Angew. Chem. Int. Ed. 2018, 57, 1068–1072 (open access [Link])
Direct Stereoselective Installation of Alkyl Fragments at the β-Carbon of Enals via Excited Iminium Ion Catalysis Charlie Verrier, Nurtalya Alandini, Cristofer Pezzetta, Mauro Moliterno, Luca Buzzetti, Hamish B. Hepburn, Alberto Vega-Peñaloza, Mattia Silvi, Paolo Melchiorre ACS Catalysis 2018, 8, 1062-1066 ([Link])
Visible-Light Excitation of Iminium Ions Enables the Enantioselective β-Alkylation of Enals Mattia Silvi, Charlie Verrier, Yannick Rey, Luca Buzzetti, and Paolo Melchiorre Nature Chem. 2017, 9, 868-873 (open access [Link])
Studies on the Enantioselective Iminium Ion Trapping of Radicals Triggered by an ElectronRelay Mechanism Ana Bahamonde, John J. Murphy, Marika Savarese, Erik Bremond, Andrea Cavalli, Paolo Melchiorre J. Am. Chem. Soc. 2017, 139, 4559-4567 (open access [Link])
Radical-based C-C Bond-Forming Processes Enabled by the Photoexcitation of 4-Alkyl-1,4- Dihydropyridines Luca Buzzetti, Alexis Prieto, Sudipta R. Roy, Paolo Melchiorre Angew. Chem. Int. Ed. 2017, 56, 15039–15043 (open access [Link])
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