个人简介
MPharm, Welsh School of Pharmacy, Cardiff, 2002
PhD, Cardiff University, 2009
研究领域
Blood Brain Barrier
Phage Display
Experimental Therapeutics
近期论文
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Jenkins, A.et al. 2016. Too far away to work with each other: Does location impact on pharmacists' perceptions of interprofessional interactions?. Journal of Interprofessional Care 30(5), pp. 678-681. (10.1080/13561820.2016.1191451) pdf
Gomez, H.et al. 2016. Herschel-ATLAS: Revealing dust build-up and decline across gas, dust and stellar mass selected samples: I. Scaling relations. Monthly Notices of the Royal Astronomical Society pdf
Aljayyoussi, G.et al. 2015. Absorption of ipratropium and L-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN transporters. International Journal of Pharmaceutics 496(2), pp. 834-841. (10.1016/j.ijpharm.2015.10.036) pdf
Aljayyoussi, G.et al. 2013. Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: A study in ex vivo lung models using chemical inhibition and genetic knockout. Journal of Pharmaceutical Sciences 102(9), pp. 3382-3394. (10.1002/jps.23587)
Campbell, L.et al. 2013. Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease. Journal of Translational Medicine 11(1), article number: 255. (10.1186/1479-5876-11-255) pdf
Smith, M. W., Aljayyoussi, G. and Gumbleton, M. 2012. Peptide sequences mediating tropism to intact blood-brain barrier: An in vivo biodistribution study using phage display. Peptides 38(1), pp. 172-180. (10.1016/j.peptides.2012.06.019)
Morris, C.et al. 2011. Enhanced pulmonary absorption of a macromolecule through coupling to a sequence-specific phage display-derived peptide. Journal of Controlled Release 151(1), pp. 83-94. (10.1016/j.jconrel.2010.12.003)
Gumbleton, M.et al. 2011. Spatial expression and functionality of drug transporters in the intact lung: objectives for further research. Advanced Drug Delivery Reviews 63(1-2), pp. 110-118. (10.1016/j.addr.2010.09.008)
Smith, M.et al. 2007. Phage display identification of functional binding peptides against 4-acetamidophenol (Paracetamol): An exemplified approach to target low molecular weight organic molecules. Biochemical and Biophysical Research Communications 358(1), pp. 285-291. (10.1016/j.bbrc.2007.04.122)