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个人简介

Education and qualifications 2013: MAcadMEd 2010: FRCP, London 2002: PhD (Neuroendocrinology) University of Wales College of Medicine, Cardiff, UK 1996: MRCP, London 1993: MB, BCh (Hons), University of Wales College of Medicine, Cardiff, UK Career overview 2015 - present: Reader in Neuroendocrinology and Honorary Consultant Endocrinologist, Neurosciences and Mental Health Research Institute, Cardiff University 2006 - 2015: Senior Lecturer and Honorary Consultant Endocrinologist, Cardiff University 2003 – 2006: Clinical Lecturer in Endocrinology, Cardiff University 2001 – 2003: Specialist Registrar in Endocrinology, South Wales 1998 – 2001: Society for Endocrinology Clinical Endocrinology Trust Research Fellow, University of Wales College of Medicine, Cardiff 1997 – 1998: Wellcome Trust Clinical Training Fellow, University of Wales College of Medicine, Cardiff 1996 – 1997: Registrar in General Medicine, Royal Gwent Hospital, Newport 1994 – 1996: Senior House Officer in Medicine, South Wales 1993 – 1994: House Officer in Medicine and Surgery, University Hospital of Wales and Llandough Hospital

研究领域

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My current studies use advanced MRI to understand the impact of the hormonal environment in early life on cognition and neurodevelopment. My group has shown altered white matter microstructure and cognitive ability in young women with Polycystic Ovary Syndrome (PCOS), building on previous epidemiological and basic science studies which have established the long-term metabolic and cardiovascular outcomes in this patient population. Our long-term follow-up study of children born to mothers in the Controlled Antenatal Thyroid Screening (CATS) trial will enable us to assess the effects of thyroid hormone exposure in pregnancy on neurodevelopment, using the state-of-the-art MRI facilities in the new Cardiff University Brain Research Imaging Centre (CUBRIC). Recent studies have also sought to explore the potential utility of extracellular vesicles, including those derived from adipocytes, as biomarkers and mediators of cardiometabolic risk in patients with obesity and PCOS.

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