Probst, Katrin - Cardiff University

个人简介

Katrin Probst obtained her first degree in General & Pharmaceutical Chemistry (Dip-Ing Chemie FH, NTA Prof Grübler, Germany) in 1994. She continued her studies at the University of Basel (Switzerland) in Organic Chemistry & Biochemist and finish in 1997 as Diplom Chemiker. After a short period at University of Basel and Roche AG, Basel (Switzerland) she took up a PhD with Prof Jung at the University of Tübingen (Germany) in Combinatorial Chemistry. During this time she extended her knowledge in Pharmacology & Toxicology, Anatomy & Physiology, Pharmaceutical Biology. From 2003-2004 Dr Probst did a Postdoc at the University of Brighton with Prof Lloyd. She joined the University of Cambridge in 2005, working at the Wolfson Brain Imaging Centre (WBIC) with Dr Aigbirhio, where she was responsible for regular synthesis of [18F]FDG, [18F]Fallypride, [11C]PK11195 and the development of [18F]DAA1106, [11C]DAA1106 to image inflamation (BHF funded, Prof Weissberg). During 2007-2008 Dr Probst completed a Postgraduate Certificate in Radiopharmaceutical Chemistry/Radiopharmacy, ETH Zurich (Switzerland) and joined the University of Edinburgh in 2008 to help set the newly established Clinical Research Imaging Centre (CRIC). In 2010 she was appointed Radiochemist for the Wales Research & Diagnostic Positron Emission Tomography Imaging Centre (PETIC) at Cardiff University.

近期论文

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Marshall, C.et al. 2015. Implementation of routine production of [18F]-fallypride on the TRASIS all-in-one universal synthesizer. European Journal of Nuclear Medicine and Molecular Imaging 42, pp. S479-S479. Meyer, J.et al. 2014. A novel radiochemical approach to 1-(2 '-deoxy-2 '-[F-18] fluoro-beta-D-arabinofuranosyl)cytosine (F-18-FAC). Journal of Labelled Compounds and Radiopharmaceuticals 57(11), pp. 637-644. (10.1002/jlcr.3233) pdf Meyer, J., Probst, K. C. and Westwell, A. D. 2014. Radiochemical synthesis of 2′-[18F]-labelled and 3′-[18F]-labelled nucleosides for positron emission tomography imaging. Journal of Labelled Compounds and Radiopharmaceuticals 57(5), pp. 333-337. (10.1002/jlcr.3197) pdf Bird, J.et al. 2010. Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis. Atherosclerosis 210(2), pp. 388-391. (10.1016/j.atherosclerosis.2009.11.047) pdf Probst, K.et al. 2007. Synthesis and evaluation of fluorine-18 and copper-64 labelled PBR radioligands. Journal of Labelled Compounds and Radiopharmaceuticals 50(5-6), pp. 561-562. (10.1002/jlcr.1274) Probst, K.et al. 2007. Strategy for improved [11C]DAA1106 radiosynthesis and in vivo peripheral benzodiazepine receptor imaging using microPET, evaluation of [11C]DAA1106. Nuclear Medicine and Biology 34(4), pp. 439-446. (10.1016/j.nucmedbio.2007.02.009) Dalley, J.et al. 2007. Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science 315(5816), pp. 1267-1270. (10.1126/science.1137073) Probst, K. C. and Jung, G. 2006. Solid-phase S-3CR generates N-substituted α-aminonitriles for the synthesis of α-phenyl-α-(1-piperazinyl) substituted amino acids. Amino Acids 30(3), pp. 243-250. (10.1007/s00726-006-0285-2) Probst, K. C. and Wessel, H. 2001. Synthesis and Conformational Investigations of Sulfated Carbohydrates[1]. Journal of Carbohydrate Chemistry 20(7&8), pp. 549. (10.1081/CAR-100108273)