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个人简介

Education and qualifications: 1995, MD research degree, University of Wales College of Medicine 1984, Primary medical degree (MB, BCh) in Clinical Medicine, Peking University Health Science Centre (Previously Beijing Medical University) Career overview: 2014 - present: Dean of International, Cardiff University 2012 - present: Director of Cardiff China Medical Research Collaborative 2012 - present: Quality and Safety Improvement Faculty, National Health Service/UHB, National Health Service 2012 - present: Academic Director for International Relations, Cardiff University 2004 - present: Professor of Surgery and Tumour Biology, Cardiff University School of Medicine 2003 - 2004: Reader, University of Wales College of Medicine 1997 - 2003: Senior Lecturer, University of Wales College of Medicine 1996 - 1997: Senior Fellow, University of Wales College of Medicine 1989 - 1996: Research Fellow, University of Wales College of Medicine (currently Cardiff University's School of Medicine) 1987 - 1989: Chief Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing 1984 - 1987: Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing

研究领域

I have a long-standing interest in cancer metastasis and from 1987, my main research interest has been on the molecular and cellular basis of cancer invasion and metastasis and therapeutic aspects of targeting cancer metastasis. I have been particularly interested in the bone, peritoneal and brain metastasis from primary tumours including breast, prostate, lung, GI cancers. My research has been conducted in Cardiff's School of Medicine and I have collaborated widely with colleagues in the UK, China, Europe, North America and Asia.

近期论文

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Owen, S.et al. 2017. ShenLingLan influences the attachment and migration of ovarian cancer cells potentially through the GSK3 pathway. Medicines 7, pp. 1-11. pdf Li, J.et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439) pdf Kourti, M., Jiang, W. and Cai, J. 2017. Aspects of carbon monoxide in form of CO-releasing molecules used in cancer treatment: More light on the way. Oxidative Medicine and Cellular Longevity 2017, article number: 9326454. (10.1155/2017/9326454) pdf Liu, Z.et al. 2017. Hepatitis B virus reactivation in breast cancer patients undergoing chemotherapy: A review and meta-analysis of prophylaxis management. Journal of Viral Hepatitis (10.1111/jvh.12672) Ablin, R. J., Owen, S. and Jiang, W. 2017. Prostate transglutaminase (TGase-4) induces epithelial-to-mesenchymal transition in prostate cancer cells. Anticancer Research 37(2), pp. 481-488. (10.21873/anticanres.11340) Wang, Z.et al. 2017. Poly lactic-co-glycolic acid controlled delivery of Disulfiram to target liver cancer stem-like cells. Nanomedicine: Nanotechnology, Biology and Medicine 13(2), pp. 641-657. (10.1016/j.nano.2016.08.001) pdf Cai, S.et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports (10.3892/or.2017.5394) pdf Telford, E., Jiang, W. G. and Martin, T. A. 2017. HAVcR-1 involvement in cancer progression. Histology and Histopathology 32, pp. 121-128. (10.14670/HH-11-817) Gu, Y.et al. 2016. NHERF1 regulates the progression of colorectal cancer through the interplay with VEGFR2 pathway. Oncotarget (10.18632/oncotarget.13949) pdf Cai, J. and Jiang, W. 2016. Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids. Oncotarget (10.18632/oncotarget.13413) pdf Shi, L.et al. 2016. Clinical and therapeutic implications of follistatin in solid tumours. Cancer Genomics and Proteomics 13(6), pp. 425-435. (10.21873/cgp.200xx) pdf

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