个人简介
Education and qualifications:
1995, MD research degree, University of Wales College of Medicine
1984, Primary medical degree (MB, BCh) in Clinical Medicine, Peking University Health Science Centre (Previously Beijing Medical University)
Career overview:
2014 - present: Dean of International, Cardiff University
2012 - present: Director of Cardiff China Medical Research Collaborative
2012 - present: Quality and Safety Improvement Faculty, National Health Service/UHB, National Health Service
2012 - present: Academic Director for International Relations, Cardiff University
2004 - present: Professor of Surgery and Tumour Biology, Cardiff University School of Medicine
2003 - 2004: Reader, University of Wales College of Medicine
1997 - 2003: Senior Lecturer, University of Wales College of Medicine
1996 - 1997: Senior Fellow, University of Wales College of Medicine
1989 - 1996: Research Fellow, University of Wales College of Medicine (currently Cardiff University's School of Medicine)
1987 - 1989: Chief Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing
1984 - 1987: Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing
研究领域
I have a long-standing interest in cancer metastasis and from 1987, my main research interest has been on the molecular and cellular basis of cancer invasion and metastasis and therapeutic aspects of targeting cancer metastasis. I have been particularly interested in the bone, peritoneal and brain metastasis from primary tumours including breast, prostate, lung, GI cancers. My research has been conducted in Cardiff's School of Medicine and I have collaborated widely with colleagues in the UK, China, Europe, North America and Asia.
近期论文
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Owen, S.et al. 2017. ShenLingLan influences the attachment and migration of ovarian cancer cells potentially through the GSK3 pathway. Medicines 7, pp. 1-11. pdf
Li, J.et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439) pdf
Kourti, M., Jiang, W. and Cai, J. 2017. Aspects of carbon monoxide in form of CO-releasing molecules used in cancer treatment: More light on the way. Oxidative Medicine and Cellular Longevity 2017, article number: 9326454. (10.1155/2017/9326454) pdf
Liu, Z.et al. 2017. Hepatitis B virus reactivation in breast cancer patients undergoing chemotherapy: A review and meta-analysis of prophylaxis management. Journal of Viral Hepatitis (10.1111/jvh.12672)
Ablin, R. J., Owen, S. and Jiang, W. 2017. Prostate transglutaminase (TGase-4) induces epithelial-to-mesenchymal transition in prostate cancer cells. Anticancer Research 37(2), pp. 481-488. (10.21873/anticanres.11340)
Wang, Z.et al. 2017. Poly lactic-co-glycolic acid controlled delivery of Disulfiram to target liver cancer stem-like cells. Nanomedicine: Nanotechnology, Biology and Medicine 13(2), pp. 641-657. (10.1016/j.nano.2016.08.001) pdf
Cai, S.et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports (10.3892/or.2017.5394) pdf
Telford, E., Jiang, W. G. and Martin, T. A. 2017. HAVcR-1 involvement in cancer progression. Histology and Histopathology 32, pp. 121-128. (10.14670/HH-11-817)
Gu, Y.et al. 2016. NHERF1 regulates the progression of colorectal cancer through the interplay with VEGFR2 pathway. Oncotarget (10.18632/oncotarget.13949) pdf
Cai, J. and Jiang, W. 2016. Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids. Oncotarget (10.18632/oncotarget.13413) pdf
Shi, L.et al. 2016. Clinical and therapeutic implications of follistatin in solid tumours. Cancer Genomics and Proteomics 13(6), pp. 425-435. (10.21873/cgp.200xx) pdf