Ingram, John - Cardiff University

个人简介

Improving the care of people with hidradenitis suppurativa is my principal research and clinical focus within dermatology. Hidradenitis suppurativa (HS) is a neglected, painful chronic inflammatory skin disease, characterised by recurrent skin boils in flexural sites, producing a large impact on quality of life and affecting about 1% of the adult European population. I run one of the few dedicated HS clinics in the UK and champion a multi-disciplinary team approach to HS care. My aim is to conduct HS clinical trials to improve patient outcomes, with the support of the UK Dermatology Clinical Trials Network and other collaborative groups. As part of laying the foundations for HS trials, I led the Cochrane review of Interventions for HS and chaired a HS Priority Setting Partnership with support from the James Lind Alliance. My research to investigate HS epidemiology, impact and outcome measures is supported by a five year Health Fellowship from Health and Care Research Wales. I am also leading the British Association of Dermatologists guideline development group for HS. In terms of international roles, I am Deputy Editor of the British Journal of Dermatology, a leading dermatology journal.

研究领域

Hidradenitis suppurativa My main research interest is hidradenitis suppurativa (HS), a relatively common, painful chronic inflammatory skin condition which can have a large impact on quality of life and may be difficult to treat. As a result, more than 50 medical and surgical interventions have been tried and our recent Cochrane review showed that the evidence base for most interventions is relatively poor, making treatment decisions challenging. I am building the foundations to perform rigorous clinical trials to improve the care of people with HS. Our HS Priority Setting Partnership between HS patients and clinicians (http://www.jla.nihr.ac.uk/priority-setting-partnerships/hidradenitis-suppurativa) highlighted the therapy areas that are most in need of more evidence. My five year Health Fellowship from Health and Care Research Wales (HCRW) is designed to provide better measures of the impact and epidemiology of HS, to demonstrate the degree of unmet need. In addition, I am undertaking a consensus project for HS outcome measures, in collaboration with the CSG-COUSIN and IDEOM international groups, to improve the definition of treatment success or failure for future clinical trials.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Ingram, J.et al. 2016. Interventions for hidradenitis suppurativa: a Cochrane systematic review incorporating GRADE assessment of evidence quality. British Journal of Dermatology 174(5), pp. 970-978. (10.1111/bjd.14418) pdf Atwan, A.et al. 2016. Oral fumaric acid esters for psoriasis: abridged Cochrane systematic review including GRADE assessments. British Journal of Dermatology 175(5), pp. 873-881. (10.1111/bjd.14676) pdf Ingram, J. R., Hadjieconomou, S. and Piguet, V. 2016. Development of core outcome sets in hidradenitis suppurativa:a systematic review of outcome measure instruments to inform the process. British Journal of Dermatology 175(2), pp. 263-272. (10.1111/bjd.14475) pdf Ingram, J. R. 2016. The genetics of Hidradenitis Suppurativa. Dermatologic Clinics 34(1), pp. 23-28. (10.1016/j.det.2015.07.002) Ingram, J.et al. 2015. Interventions for hidradenitis suppurativa. Cochrane Database of Systematic Reviews (10), article number: CD010081. (10.1002/14651858.CD010081.pub2) Ingram, J. R. and Paul, C. 2015. Academic mentorship in dermatology. British Journal of Dermatology 173(5), pp. 1113-1114. (10.1111/bjd.14197) Ingram, J. and McPhee, M. 2015. Management of hidradenitis suppurativa: a UK survey of current practice. British Journal of Dermatology 173(4), pp. 1070-1072. (10.1111/bjd.13866) Ingram, J. R. and McPhee, M. 2015. Management of hidradenitis suppurativa: a UK survey of current practice. British Journal of Dermatology 173(4), pp. 1070-1072. (10.1111/bjd.13866) Atwan, A.et al. 2015. Oral fumaric acid esters for psoriasis. Cochrane Database of Systematic Reviews 8, article number: CD010497. (10.1002/14651858.CD010497.pub2)