Hall, Jeremy - Cardiff University

个人简介

My overarching interest is in the role of genetic and environmental risk factors in the development of neurodevelopmental disorders such as schizophrenia and autism and related personality disorders. In my work I employ a translational approach to study how genetic and environmental factors enhance risk for mental illness. I am particularly interested in how identified genetic risk factors affect learning processes in the brain, abnormalities in which underlie the key symptoms seen in a range of mental health problems. Overall I believe that understanding of how genetic risk factors influence the brain and how these responses are modulated by environmental stimuli is crucial to the development of new treatments for psychiatric illness. In addition to my pre-clinical work I also conduct clinical work and research in the fields of adult neurodevelopmental disorders and early psychosis.

研究领域

Current research projects: Role of psychiatric risk genes in learning and memory. Expression and regulation of autism and schizophrenia associated genes. Modulatory effects of early life experience on gene expression and psychiatric risk. Genetic effects on brain structure and function.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Clifton, N.et al. 2017. Schizophrenia copy number variants and associative learning. Molecular Psychiatry 22(2), pp. 178-182. (10.1038/mp.2016.227) pdf Foley, S.et al. 2017. Multimodal brain imaging reveals structural differences in Alzheimer's disease polygenic risk carriers: A study in healthy young adults. Biological psychiatry 81(2), pp. 154-161. (10.1016/j.biopsych.2016.02.033) pdf Thomson, P.et al. 2016. Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. npj Schizophrenia 2, article number: 16024. (10.1038/npjschz.2016.24) pdf Chan, S.et al. 2016. Deactivation in anterior cingulate cortex during facial processing in young individuals with high familial risk and early development of depression: fMRI findings from the Scottish Bipolar Family Study. Journal of Child Psychology and Psychiatry (10.1111/jcpp.12591) pdf Scholz, B.et al. 2016. The regulation of cytokine networks in hippocampal CA1 differentiates extinction from those required for the maintenance of contextual fear memory after recall. PLoS ONE 11(5), article number: e0153102. (10.1371/journal.pone.0153102) pdf Schmaal, L.et al. 2016. Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry (10.1038/mp.2016.60) pdf Papmeyer, M.et al. 2015. Neurocognition in individuals at high familial risk of mood disorders with or without subsequent onset of depression. Psychological Medicine 45(15), pp. 3317-3327. (10.1017/S0033291715001324) Johnstone, M.et al. 2015. Copy number variations in DISC1 and DISC1-interacting partners in major mental illness. Molecular Neuropsychiatry 1(3), pp. 175-190. (10.1159/000438788) pdf