Orozco-terWengel, Pablo - Cardiff University

个人简介

2005-2011 Doctor in Natural Sciences Veterinary University of Vienna (Vienna, Austria) Thesis Work: Population Genetics of Drosophila (Advisor Dr. Christian Schlötterer) 2003-2005 MSc. (Honors) Universiteit van Amsterdam (Amsterdam, The Netherlands) Thesis Work (1): Population Genetics of Dyscophus (Advisor: Dr. Miguel Vences) Thesis Work (2): Detecting Natural Selection in Hybrids of Lactuca sativa and Lactuca serriola (Advisor: Dr. Danny Hooftman) 1997-2003 B.Sc. (Honors) Pontificia Universidad Javeriana (Bogota, Colombia) Thesis Work: Population Genetic Analysis of the Andean bear by means of 12 microsatellite polymorphic loci (Advisor: Dr. Manuel Ruiz-Garcia)

研究领域

I have always been amazed by the diversity of animals and plants. This interest led me to study biology where I learned about population genetics and the possibility of inferring species evolutionary history using molecular markers. My work focuses on using neutral genetic markers (e.g. microsatellites) to understand the interplay between the genealogical history of populations (or species) and their distribution over space and time. However, since the arrival of next generation sequencing I've also become interested in using the power of genomics (e.g. whole genome sequencing) to search for genomic regions involved in the process of local adaptation (e.g. adaptation to temperature or diseases). Understanding how adaptation takes place is extremely important in order to develop frameworks that will help us coping with climate change and ensure species survival into the future. My work covers both wild life (e.g. Malagasy amphibians and South American bears) and domestic taxa (e.g. Iranian sheep and Moroccan goats), and uses a combination of laboratory techniques and bioinformatics.

近期论文

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Valbuena-Ureña, E.et al. 2017. No signs of inbreeding despite long-term isolation and habitat fragmentation in the critically endangered Montseny brook newt (Calotriton arnoldi). Heredity (10.1038/hdy.2016.123) pdf Liu, Z.et al. 2016. Dietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals. Frontiers in Zoology 13(1), article number: 28. (10.1186/s12983-016-0161-1) pdf Almathen, F.et al. 2016. Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary. Proceedings of the National Academy of Sciences of the United States of America 113(24), pp. 6707-6712. (10.1073/pnas.1519508113) Sherrard-Smith, E.et al. 2016. Distribution and molecular phylogeny of biliary trematodes (Opisthorchiidae) infecting native Lutra lutra and alien Neovison vison across Europe. Parasitology International 65(2), pp. 163-170. (10.1016/j.parint.2015.11.007) pdf Orozco Ter Wengel, P. 2016. The devil is in the details: the effect of population structure on demographic inference. Heredity 116, pp. 349-350. (10.1038/hdy.2016.9) Bruford, M.et al. 2015. Prospects and challenges for the conservation of farm animal genomic resources, 2015-2025. Frontiers in Genetics 6, article number: 314. (10.3389/fgene.2015.00314) pdf MacLeod, A.et al. 2015. Hybridization masks speciation in the evolutionary history of the Galápagos marine iguana. Proceedings of the Royal Society B: Biological Sciences 282(1809), article number: 20150425. (10.1098/rspb.2015.0425) Orozco Ter Wengel, P.et al. 2015. Revisiting demographic processes in cattle with genome-wide population genetic analysis. Frontiers in Genetics 6, article number: 191. (10.3389/fgene.2015.00191) pdf Gonzalez, B.et al. 2014. Maintenance of genetic diversity in an introduced island population of guanacos after seven decades and two severe demographic bottlenecks: Implications for camelid conservation. PLoS ONE 9(3), article number: e91714. (10.1371/journal.pone.0091714) pdf Cunha, L.et al. 2014. Living on a volcano's edge: genetic isolation of an extremophile terrestrial metazoan. Heredity 112(2), pp. 132-142. (10.1038/hdy.2013.84)