Lello, Joanne - Cardiff University - School of Biosciences

个人简介

I started out as a junior medical laboratory scientist in microbiology at Liverpool PHLS, but returned to education undertaking an Applied Biology degree at Liverpool John Moores University. Following my degree I spent several years studying squirrel behaviour and disease before taking up a PhD in December 1999 at Stirling University under the guidance of Prof. Peter Hudson. It was there that my interest in coinfection began while studying the "Community Ecology of Rabbit (Oryctolagus cuniculus) Parasites". After completion of the PhD in May 2006 I moved to Armidale (NSW, Australia), to take up a position as a Research Scientist in CSIRO Livestock Industries extending my coinfection research to examine the immune mechanisms mediating parasite interspecific interactions in sheep. Finally after three years down-under I returned to the UK and gained my position as a Lecturer here in Cardiff.

研究领域

My research focuses on the over-arching question, 'What are the consequences of coinfection for the spread and evolution of infectious disease?" Within this broader question I explore three key areas: Detection – Developing statistical approaches to aid in determining the presence and form of interspecific parasite interactions in natural systems. Interaction Mechanisms - Elucidating the form of the interactions between the parasite species. Prediction – Examining the dynamic consequence of the parasite inter-specific interactions for both the hosts and parasites, with particular respect to parasite transmission and host-parasite evolution.

近期论文

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Hamish, M.et al. 2017. Breaking beta:deconstructing the parasite transmission function. Philosophical Transactions of the Royal Society of London Series B - Biological Sciences (10.1098/rstb.2016.0084) pdf Lello, J. and Fenton, A. 2017. Lost in transmission ...?. Philosophical Transactions B Randall, J.et al. 2013. Endemic infection reduces transmission potential of an epidemic parasite during co-infection. Proceedings of the Royal Society B: Biological Sciences 280(1769), article number: 20131500. (10.1098/rspb.2013.1500) pdf Lello, J. 2013. Coinfection: Doing the math. Science Translational Medicine 5(191), article number: 191fs24. (10.1126/scitranslmed.3006565) Lello, J.et al. 2013. The relative contribution of co-infection to focal infection risk in children. Proceedings of the Royal Society B: Biological Sciences 280(1754), article number: 20122813. (10.1098/rspb.2012.2813) pdf Lum, E.et al. 2012. Co-infections of malaria and soil-transmitted helminths in localities with different levels of urbanisation in the Mount Cameroon region [Poster]. Onderstepoort Journal of Veterinary Research 79(2), article number: 488. (10.4102/ojvr.v79i2.487) Hunt, P. W. and Lello, J. 2012. How to make DNA count: DNA-based diagnostic tools in veterinary parasitology. Veterinary Parasitology 186(1-2), pp. 101-108. (10.1016/j.vetpar.2011.11.055) Fenton, A., Viney, M. and Lello, J. 2010. Detecting interspecific macroparasite interactions from ecological data: patterns and process. Ecology Letters 13(5), pp. 606-615. (10.1111/j.1461-0248.2010.01458.x) Harwood, J.et al. 2009. Invertebrate biodiversity affects predator fitness and hence potential to control pests in crops. Biological Control 51(3), pp. 499-506. (10.1016/j.biocontrol.2009.09.007) Lello, J. and Hussell, T. 2008. Functional group/guild modelling of inter-specific pathogen interactions: A potential tool for predicting the consequences of co-infection. Parasitology 135(7), pp. 825-839. (10.1017/S0031182008000383) pdf Lello, J.et al. 2008. Pathogen interactions, population cycles, and phase shifts. American Naturalist 171(2), pp. 176-182. (10.1086/525257) pdf