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研究领域

Heavy metals are essential for life, however, paradoxically exploitation of land for mineral extraction and manufacturing industry results in the release of large quantities of heavy metals that can be toxic to the natural environment. My research portfolio is designed to exploit state-of-the-art genomic, proteomic and metabolomic techniques to study the mechanisms by which biological systems handle heavy metals assessing: their impact as pollutants, their involvement in disease and the basic mechanisms by which they are bound within biological systems.

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Morris, C.et al. 2017. Quantitative analysis of gene expression changes in response to genotoxic compounds. Toxicology in Vitro 39, pp. 15-28. (10.1016/j.tiv.2016.11.004) pdf Spurgeon, D.et al. 2016. Ecological drivers influence the distributions of two cryptic lineages in an earthworm morphospecies. Applied Soil Ecology 108, pp. 8-15. (10.1016/j.apsoil.2016.07.013) pdf Gonçalves, S.et al. 2016. Sub-lethal cadmium exposure increases phytochelatin concentrations in the aquatic snail Lymnaea stagnalis. Science of the Total Environment 568, pp. 1054-1058. (10.1016/j.scitotenv.2016.06.149) Jones, G.et al. 2016. The worm has turned: behavioural drivers of reproductive isolation between cryptic lineages. Soil Biology & Biochemistry 98, pp. 11-17. (10.1016/j.soilbio.2016.03.015) pdf Taylor, K.et al. 2016. Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration. Biochemical Journal 473, pp. 2531-2544. (10.1042/BCJ20160388) pdf Evans, M.et al. 2016. First known satellite collaring of a viverrid species: preliminary performance and implications of GPS tracking Malay civets (Viverra tangalunga). Ecological Research 31(3), pp. 475-481. (10.1007/s11284-016-1338-y) pdf Cunha, L.et al. 2016. Soil animals and pedogenesis: The role of earthworms in anthropogenic soils. Soil Science 181(3/4), pp. 110-125. Kille, P.et al. 2016. Venus trapped, Mars transits: Cu and Fe redox chemistry, cellular topography, and in situ ligand binding in terrestrial isopod hepatopancreas. Open Biology 6(3), article number: 150270. (10.1098/rsob.150270) pdf Tourinho, P.et al. 2015. Toxicokinetics of Ag in the terrestrial isopod Porcellionides pruinosus exposed to Ag NPs and AgNO3 via soil and food. Ecotoxicology 25(2), pp. 267-278. (10.1007/s10646-015-1585-7) Novo Rodriguez, M.et al. 2015. Different routes, same pathways: molecular mechanisms under silver ion and nanoparticle exposures in the soil sentinel Eisenia fetida. Environmental Pollution 205, pp. 385-393. (10.1016/j.envpol.2015.07.010) pdf Guler, Y.et al. 2015. Impacts of a newly identified behaviour-altering trematode on its host amphipod: from the level of gene expression to population. Parasitology 142(12), pp. 1469-1480. (10.1017/S0031182015000918)

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