Kemp, Paul - Cardiff University - School of Biosciences

个人简介

I graduated from The University of Leeds with a BSc in Physiology in 1986 and from Oxford University with a DPhil in Physiology in 1989. I held a post-doctoral post in The University of Manchester, a position of lecturer at the University of Dundee and was a Human Frontiers Science Programme Fellow at The University of Southern California. I joined The School of Biomedical Sciences at Leeds University in November 1997. I took up a Chair in Physiology at Cardiff University on 1st September 2004.

研究领域

My complementary research interests are in the general areas of regenerative medicine and respiratory molecular physiology, and are: Human ES and iPS cell fate-determination, function and pathology, with specific emphasis on Huntington's Disease (Patch-clamp and calcium imaging). Calcium sensing receptor in airway signal transduction and inflammatory lung diseases;. Molecular physiology of O2 sensing ion channels (K2P KCa and P2X channels); Genetically encoded sensor/transducer systems for programmed cell death in cell replacement therapies (unnatural amino acid synthetic biology).

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Kemp, P.et al. 2016. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology 594(22), pp. 6583-6594. (10.1113/JP270655) pdf Brazier, S. P., Telezhkin, V. and Kemp, P. J. 2016. Functional interactions between BKCaα-Subunit and Annexin A5: implications in apoptosis. Oxidative Medicine and Cellular Longevity 2016, article number: 1607092. (10.1155/2016/1607092) pdf Stephen P., B., Telezhkin, V. and Kemp, P. 2016. Functional Interactions between BKCa a-subunit and Annexin A5: implications in apoptosis. Oxidative Medicine and Cellular Longevity 2016, article number: 1607092. pdf Young, F.et al. 2016. Clonal heterogeneity in the neuronal and glial differentiation of dental pulp stem/progenitor cells. Stem Cells International , pp. 1-10., article number: 1290561. (10.1155/2016/1290561) pdf Brennan, S.et al. 2016. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Scientific Reports 6, article number: 21975. (10.1038/srep21975) pdf Schepelmann, M.et al. 2016. The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure. American Journal of Physiology - Cell Physiology 310(3), pp. C193-C204., article number: ajpcell.00248.2015. (10.1152/ajpcell.00248.2015) pdf Telezhkin, V.et al. 2015. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3? signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology - Cell Physiology , article number: ajpcell.00166.2015. (10.1152/ajpcell.00166.2015) Straccia, M.et al. 2015. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy - Methods & Clinical Development 2, article number: 15030. (10.1038/mtm.2015.30)