Gerasimenko, Julia - Cardiff University

研究领域

Investigation of the involvement of pathological substances including bile, alcohol and non-oxidative alcohol metabolites in the initiation of acute pancreatitis. Physiological calcium signalling in pancreatic acinar cells including actions of nicotinic acid adenine dinucleotide phosphate (NAADP) and its role in physiology and pathology of exocrine pancreas. Development of two-photon microscopy applications for studies of exocrine pancreas

近期论文

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Ferdek, P.et al. 2017. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides. Cell Death and Disease pdf Ferdek, P.et al. 2016. Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium-driven bile uptake. The Journal of Physiology 594(21), pp. 6147-6164. (10.1113/JP272774) pdf Jakubowska, M.et al. 2016. Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biology 6(8), pp. 160149. (10.1098/rsob.160149) pdf Peng, S.et al. 2016. Calcium and ATP control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philosophical Transactions of the Royal Society B: Biological Sciences 371(1700) pdf Gryshchenko, O.et al. 2016. Calcium signalling in pancreatic stellate cells: mechanisms and potential roles. Cell Calcium 59(2-3), pp. 140-144. (10.1016/j.ceca.2016.02.003) Gryshchenko, O.et al. 2016. Ca2+ signals mediated by bradykinin type 2 receptors in normal pancreatic stellate cells can be inhibited by specific Ca2+ channel blockade. The Journal of Physiology 594(2), pp. 281-293. (10.1113/JP271468) pdf Gerasimenko, J.et al. 2015. Both RyRs and TPCs are required for NAADP-induced intracellular Ca2+ release. Cell Calcium 58(3), pp. 237-245. (10.1016/j.ceca.2015.05.005) pdf Gerasimenko, J. V., Peng, S. and Gerasimenko, O. V. 2014. Role of acidic stores in secretory epithelia. Cell Calcium 55(6), pp. 346-354. (10.1016/j.ceca.2014.04.002) Gerasimenko, J. V., Petersen, O. H. and Gerasimenko, O. V. 2014. Monitoring of intra-ER free Ca2+. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling 3(3), pp. 63-71. (10.1002/wmts.106)