周作民 - 南京医科大学

个人简介

Education: A.B. Harvard University, Ph.D. University of California at Berkeley Awards: Awards: Hans Bloemendal Award (Radboud Univ. Nijmegen) (2013); Heinrich Wieland Prize (2012); Tetrahedron Young Investigator Award (2011); Lemelson-MIT Prize (2010); Albert Hofmann Medal (Univ. Zurich) (2009); Harrison Howe Award (2009); W. H. Nichols Award (2009); Willard Gibbs Medal (2008); Roy L. Whistler International Award in Carbohydrate Chemistry (2008); Li Ka Shing Women in Science Award (2008); Ernst Schering Prize (2007); T.Z. and Irmgard Chu Distinguished Professorship in Chemistry, UC Berkeley (2005-14); Havinga Medal, Univ. Leiden (2005); Iota Sigma Pi Agnes Fay Morgan Research Award (2004); Irving Sigal Young Investigator Award of the Protein Society (2002); Fellow of the American Association for the Advancement of Science (2002); Donald Sterling Noyce Prize for Excellence in Undergraduate Teaching (2001); UC Berkeley Distinguished Teaching Award (2001); ACS Award in Pure Chemistry (2001); Merck Academic Development Program Award (2000); UC Berkeley Department of Chemistry Teaching Award (2000); Presidential Early Career Award in Science and Engineering (PECASE) (2000); MacArthur Foundation “Genius” Award (1999); Camille Dreyfus Teacher-Scholar Award (1999); Arthur C. Cope Scholar Award (ACS) (1999); Beckman Young Investigator Award (1998); Prytanean Faculty Award (1998); Glaxo Wellcome Scholar (1998); Research Corporation Research Innovation Award (1998); Office of Naval Research Young Investigator Award (1998); Horace S. Isbell Award in Carbohydrate Chemistry (ACS) (1997); Alfred P. Sloan Research Fellow (1997); Burroughs Wellcome New Investigator Award in Pharmacology (1997); Pew Scholars Award in the Biomedical Sciences (1996); Exxon Education Fund Young Investigator Award (1996); Camille and Henry Dreyfus New Faculty Award (1995) Academy memberships: Elected member of the National Academy of Sciences (2005), Institute of Medicine (2011), German Academy of Sciences Leopoldina (2008), the American Academy of Arts and Sciences (2003), and the National Academy of Inventors (2013) Honorary degrees: Honorary Doctorate Degree, Brown University (2012) Honorary Doctorate Degree, Duke University (2014) Honorary Degree, Freie Univ. Berlin (2014) Chemistry Research Area: Chemical Biology Organic

研究领域

The Bertozzi Group studies cell surface interactions that contribute to human health and disease with specific projects in the areas of cancer, inflammation and bacterial infection. We use the techniques of organic synthesis, genetics, and biochemistry as tools to study and manipulate complex cellular processes. Much of our research involves cell surface oligosaccharides, biopolymers that contribute to cell surface recognition and cell-cell communication. Bioorthogonal chemistry: Reaction methodology in the service of biology In vivo imaging of glycans and other biomolecules Glycoproteomics-based discovery of cancer and stem cell biomarkers Glycocalyx engineering toward probing cancer glycome evolution Site-specific protein modification for enhanced biotherapeutics New drug targets for Mycobacterium tuberculosis therapy

近期论文

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发表论文： 1.GuoX,ZhangP,QiY,ChenW,ChenX,ZhouZ*,ShaJ.Proteomicanalysisofmale4Cgermcellproteinsinvolvedinmousemeiosis.Proteomics.2011Jan;11(2):298-308.doi:10.1002/pmic.200900726.Epub2010Dec10. 2.?WangN,ZhangP,GuoX,ZhouZ,ShaJ*.Hnrnpk,aproteindifferentiallyexpressedinimmatureratovariandevelopment,isrequiredfornormalprimordialfollicleassemblyanddevelopment.Endocrinology.2011Mar;152(3):1024-35.Epub2010Dec29. 3.?WangL,ChenW,ZhaoC,HuoR,GuoXJ,LinM,HuangXY,MaoYD*,ZhouZM*,ShaJH.Theroleofezrin-associatedproteinnetworkinhumanspermcapacitation.AsianJAndrol.2010Sep;12(5):667-76.Epub2010Aug16. 4.WangH,ChenXX,WangLR,MaoYD*,ZhouZM*,ShaJH.AF-2364isaprospectivespermicidecandidate.AsianJAndrol.2010May;12(3):322-35. 5.?GuoX,ShenJ,XiaZ,ZhangR,ZhangP,ZhaoC,XingJ,ChenL,ChenW,LinM,HuoR,SuB,ZhouZ*,ShaJ.Proteomicanalysisofproteinsinvolvedinspermiogenesisinmouse.JProteomeRes.2010Mar5;9(3):1246-56. 6.?HuangXY,GuoXJ,ShenJ,WangYF,ChenL,XieJ,WangNL,WangFQ,ZhaoC,HuoR,LinM,WangXR,ZhouZM*,ShaJH.ConstructionofaProteomeProfileandFunctionalAnalysisoftheProteinsInvolvedintheInitiationofMouseSpermatogenesis.JProteomeRes.2008Aug;7(8):3435-46.Epub2008Jun27 7.ZhangKM,WangYF,HuoR,BiY,LinM,ShaJH,ZhouZM*.CharacterizationofSpindlin1isoform2inmousetestis.AsianJAndrol.2008Sep;10(5):741-8. 8.ZhouZM,RenX,HuangXY,LuL,XuM,YinLL,LiJM,ShaJH.SMYD3-NY,anovelSMYD3mRNAtranscriptvariant,mayhavearoleinhumanspermatogenesis.AnnClinLabSci2005;35(3):270-277 9.ShaJH,ZhouZM*,LiJM,LinM,ZhuH,ZhuH,ZhouYD,WangLR,WangYQ,ZhouKY.ExpressionofanovelbHLH-Zipgeneinhumantestis.AsianJournalofAndrology2003;2:83-88 10.ZhouZM*,ShaJH,LiJM,LinM,ZhuH,ZhouYD,WangLR,ZhuH,WangYQ,ZhouKY.Expressionofanovelreticulon-likegeneinhumantestis.Reproduction2002,123:227