Nash, Debbie - Aberystwyth University - Institute of Biological, Environmental and Rural Sciences

个人简介

I gained my Ph.D. at The Royal Veterinary College, University of London in 2007. My research developed in vivo and in vitro models to enhance the study of the innate immune response to breeding-induced endometritis in mares which is a significant cause of infertility. During this time I gained a range of laboratory skills and was involved in four animal trials including taking sole lead of one. Consequently I am a personal Home Office licence holder and am competent in a range of reproductive and clinical procedures such as ultrasound of the reproductive tract, blood sampling and uterine biopsy. I joined Aberystwyth University as a Lecturer in Equine and Animal Science in 2007. I lead undergraduate to MSc modulesI also supervise PhD and MPhil students. The projects I supervise tend to include developing an ex vivo tissue culture technique as a potential anti-inflammatory screening test, testing potential anti-inflammatory compounds. I've also dabbled in population genetics with collaboration of colleagues in our state-of-the-art genomics facility. I am an active member of the British Society for Animal Science Programme Committee, taking responsibility for arranging the equine sessions on several occasions, as well as chairing sessions each year. In 2011 I was invited onto the consultative committee for setting up the Register of Animal Scientists and in 2012 was invited and elected to the BSAS Council. In addition, I am the founder, organiser and chair of the Colloquium for Equine Reproduction (http://users.aber.ac.uk/dmn/cfer/Homepage.html), which since its inaugural event in 2010, goes from strength to strength. A further event was held in 2011 and CFER was hosted within the BSAS annual conference in 2013 and in 2015.

研究领域

Reproductive physiology (specifically uterine inflammatory disease of horses and cattle); native pony population genetics.

近期论文

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Clamp, R., Creevey, C., Natoli, M., Barnea, E.R., Nash, D., Rose, M. 2016. Interaction of preimplantation factor with the bovine global endometrial transcriptome. British Society of Animal Science Annual conference, Chester, United Kingdom of Great Britain and Northern Ireland, 06/04/2016 - 07/04/2016. Winton, C.L., Plant, Y., Hind, P., McMahon, R., Hegarty, M., McEwan, N., Davies-Morel, M., Powell, W., Nash, D. 2015. Comparative genetic diversity in a sample of pony breeds from the UK and North America: A case study in the conservation of global genetic resources. Ecology and Evolution 5 (16) pp. 3507-3522. Cadair Clamp, R., Natoli, M., Barnea, E.R., Nash, D., Rose, M. 2015. Effect of preimplantation factor in an in vitro model of bovine E. coli endometritis. Proceedings of the British Society of Animal Science, Chester, United Kingdom of Great Britain and Northern Ireland, 14/04/2015 - 15/04/2015. Clamp, R., Natoli, M., Barnea, E.R., Rose, M., Nash, D. 2015. Effect of preimplantation factor in response to a LPS challenge on bovine endometrial IL-6 secretion and expression. International Conference on Biology and Pathology of Reproduction in Domestic Animals, Gdansk, Poland, 28/09/2015 - 30/09/2015. Morrell, J., Georgakas, A., Lundeheim, N., Nash, D.M., Davies-Morel, M.C.G., Johannison, A. 2014. Effect of heterologous and homologous seminal plasma on stallion sperm quality. Theriogenology 82 pp. 176-183. Cadair Clamp, R.E., Paddison, J.S., Nash, D.M., Rose, M.T., Barnea, E. 2014. Effect of pre-implantation factor on the secretion of prostaglandin F2α and prostaglandin E2 from bovine endometrial tissue following a lipopolysaccharide challenge in vitro. BSAS Annual Conference 2014, 29-30 April 2014, Nottingham, United Kingdom of Great Britain and Northern Ireland, 29/04/2014 - 30/04/2014. pp. 207. Ross, A., Nash, D.M., Paddison, J. 2014. The validation of a novel protocol for the culture of equine endometrial epithelial and stromal cells. BSAS Annual Conference 2014, 29-30 April 2014, Nottingham, United Kingdom of Great Britain and Northern Ireland, 29/04/2014 - 30/04/2014. pp. 58. Ross, A., Paddison, J.S., Nash, D.M. 2014. Validation of a novel culture protocol for equine endometrial cells as a model to investigate uterine inflammation. UFAW Welfare Conference, York, United Kingdom of Great Britain and Northern Ireland, 26/06/2014. pp. 72.