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研究领域

Reinhard's research interests encompass epigenetic mechanisms of nucleic acid modifications, chromatin, non-coding RNAs, epigenetic inheritance, gene-environment interactions and energy metabolism.

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ST?GER, REINHARD, WILLIAMS, PAULA, SHEPHARD, FREYA and CHAKRABARTI, LISA, 2017. Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson's disease npj Parkinson's Disease. 3(1), 6 SINCLAIR, KEVIN, RUTHERFORD, KENNETH, WALLACE, JACQUELINE, BRAMELD, JOHN, ST?GER, REINHARD, ALBERIO, RAMIRO, SWEETMAN, DYLAN, GARDNER, DAVID, PERRY, VIV, ADAM, CLARE and OTHERS, 2016. Epigenetics and developmental programming of welfare and production traits in farm animals Reproduction, Fertility and Development. CHOI, MINSEUNG, GENEREUX, DIANE P., GOODSON, JAMIE, AL-AZZAWI, HANEEN, ALLAIN, SHANNON Q., PALASEK, STAN, WARE, CAROL B., CAVANAUGH, CHRIS, MILLER, DANIEL G., JOHNSON, WINSLOW C., SINCLAIR, KEVIN D., ST?GER, REINHARD and LAIRD, CHARLES D., 2016. Evaluating the Stability and Flexibility of DNA Methylation Patterns from Stem to Differentiated Cells bioRxiv. TARALE P, SIVANESAN S, DAIWILE AP, ST?GER R, BAFANA A, NAOGHARE PK, PARMAR D, CHAKRABARTI T and KANNAN K, 2016. Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson's disease-associated genes. Archives of toxicology. (In Press.) ST?GER, REINHARD, 2015. A as in actor: A 6mAshing performance BIOESSAYS. 37(11), 1152-1152 DERECKA K, BLYTHE MJ, MALLA S, GENEREUX DP, GUFFANTI A, PAVAN P, MOLES A, SNART C, RYDER T, ORTORI CA, BARRETT DA, SCHUSTER E and ST?GER R, 2013. Transient exposure to low levels of insecticide affects metabolic networks of honeybee larvae PLOS ONE. 8(7):e68191., FU, A.Q., GENEREUX, D.P., ST?GER, R., BURDEN, A.F., LAIRD, C.D. and STEPHENS, M., 2012. Statistical inference of in vivo properties of human DNA methyltransferases from double-stranded methylation patterns PLoS ONE. 7(3), e32225 ST?GER, REINHARD, 2012. Epigenetic Epidemiology of Obesity, Type 2 Diabetes, and Metabolic Disorders. In: MICHELS, KARIN B., ed., Epigenetic Epidemiology Springer Netherlands. 401-421 ST?GER, R., GENEREUX, D.P., HAGERMAN, R.J., HAGERMAN, P.J., TASSONE, F. and LAIRD, C.D., 2011. Testing the Fmr1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in Fmr1-expressing males with fragile X syndrome. PLoS ONE. 6(8), e23648 LATHROP, M.J., CHAKRABARTI, L., ENG, J., RHODES, C.H., LUTZ, T., NIETO, A., LIGGITT, H.D., WARNER, S., FIELDS, J., ST?GER, R. and FIERING, S., 2010. Deletion of the Chd6 exon 12 affects motor coordination Mammalian Genome. 21(3-4), 130-142 VOUTSINAS, G.E., STAVROU, E.F., KAROUSOS, G., DASOULA, A., PAPACHATZOPOULOU, A., SYRROU, M., VERKERK, A.J.M.H., VAN DER SPEK, P., PATRINOS, G.P., ST?GER, R. and ATHANASSIADOU, A., 2010. Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wild-type and p.Ala53Thr alleles in Parkinson disease Human Mutation. 31(6), 685-91 FERTEY J, AMMERMANN I, WINKLER M, ST?GER R, IFTNER T and STUBENRAUCH F, 2010. Interaction Of The Papillomavirus E8--E2c Protein With The Cellular Chd6 Protein Contributes To Transcriptional Repression. Journal Of Virology. 84(18), 9505-15 FU AQ, GENEREUX DP, ST?GER R, LAIRD CD and STEPHENS M, 2010. Statistical Inference Of Transmission Fidelity Of Dna Methylation Patterns Over Somatic Cell Divisions In Mammals. The Annals Of Applied Statistics. 4(2), 871-892 GENEREUX, D.P., JOHNSON, W.C., BURDEN, A.F., ST?GER, R. and LAIRD, C.D., 2008. Errors in the bisulfite conversion of DNA: modulating inappropriate- and failed-conversion frequencies Nucleic Acids Research. 36(22), e150 ST?GER, REINHARD, 2008. The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes? BioEssays. 30(2), 156-66 ST?GER, REINHARD, 2008. Epigenetics and obesity. Pharmacogenomics. 9(12), 1851-60 MCCLOSKEY, MEGAN L, ST?GER, REINHARD, HANSEN, R SCOTT and LAIRD, CHARLES D, 2007. Encoding PCR products with batch-stamps and barcodes. Biochemical Genetics. 45(11-12), 761-7 LUTZ, THOMAS, ST?GER, REINHARD and NIETO, AMELIA, 2006. CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis. FEBS Letters. 580(25), 5851-7 ST?GER, REINHARD, 2006. In vivo methylation patterns of the leptin promoter in human and mouse. Epigenetics : official journal of the DNA Methylation Society. 1(4), 155-62 TISCHKOWITZ, M D, MORGAN, N V, GRIMWADE, D, EDDY, C, BALL, S, VORECHOVSKY, I, LANGABEER, S, ST?GER, R, HODGSON, S V and MATHEW, C G, 2004. Deletion and reduced expression of the Fanconi anemia FANCA gene in sporadic acute myeloid leukemia. Leukemia. 18(3), 420-5 LAIRD, CHARLES D, PLEASANT, NICOLE D, CLARK, AARON D, SNEEDEN, JESSICA L, HASSAN, K M ANWARUL, MANLEY, NATHAN C, VARY, JAY C, MORGAN, TODD, HANSEN, R SCOTT and ST?GER, REINHARD, 2004. Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 101(1), 204-9 MINER, BROOKS E, ST?GER, REINHARD J, BURDEN, ALICE F, LAIRD, CHARLES D and HANSEN, R SCOTT, 2004. Molecular barcodes detect redundancy and contamination in hairpin-bisulfite PCR. Nucleic Acids Research. 32(17), e135 SCHUSTER, EUGENE F and ST?GER, REINHARD, 2002. CHD5 defines a new subfamily of chromodomain-SWI2/SNF2-like helicases. Mammalian Genome. 13(2), 117-9 HANSEN, R S, ST?GER, R, WIJMENGA, C, STANEK, A M, CANFIELD, T K, LUO, P, MATARAZZO, M R, D'ESPOSITO, M, FEIL, R, GIMELLI, G, WEEMAES, C M, LAIRD, C D and GARTLER, S M, 2000. Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant. Human Molecular Genetics. 9(18), 2575-87 KISPERT, A, ST?GER, R J, CAPARROS, M and HERRMANN, B G, 1999. The mouse Rsk3 gene maps to the Leh66 elements carrying the t-complex responder Tcr. Mammalian Genome. 10(8), 794-802

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