Coneyworth, Lisa - University of Nottingham

个人简介

Dr Lisa Coneyworth graduated from Newcastle University in 2005 with a first class honours degree in Food and Human Nutrition. She studied for her PhD in the Institute of Cellular and Molecular Nutrition at Newcastle University, under the supervision of Professor Dianne Ford and Professor John Mathers. She graduated in 2009 and went on to complete a period of post doctoral work at Nottingham University in the Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM). Her research expertise lies in the area of epigenetics including the role of epigenetics in zinc regulated gene expression, genetic and non genetic influences during pregnancy on DNA methylation and the effect of specific nutrient exposure on epigenetic modifications in human embryonic stem cells.

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BOSOMWORTH HJ, THORNTON JK, CONEYWORTH LJ, FORD D and VALENTINE RA, 2012. Efflux function, tissue-specific expression and intracellular trafficking of the zn transporter znt10 indicate roles in adult zn homeostasis. Metallomics : integrated biometal science. (In Press.) MCKAY JA, GROOM A, POTTER C, CONEYWORTH LJ, FORD D, MATHERS JC and RELTON CL, 2012. Genetic and non-genetic influences during pregnancy on infant global and site specific dna methylation: role for folate gene variants and vitamin b12. Plos one. 7(3), e33290 CONEYWORTH LJ, JACKSON KA, TYSON J, BOSOMWORTH HJ, VAN DER HAGEN E, HANN GM, OGO OA, SWANN DC, MATHERS JC, VALENTINE RA and FORD D, 2012. Identification of the human zinc transcriptional regulatory element (ZTRE): a palindromic protein-binding DNA sequence responsible for zinc-induced transcriptional repression. The Journal of biological chemistry. 287(43), 36567-81 CONEYWORTH LJ, MATHERS JC and FORD D, 2009. Does promoter methylation of the slc30a5 (znt5) zinc transporter gene contribute to the ageing-related decline in zinc status? The proceedings of the nutrition society. 68(2), 142-7 JACKSON KA, VALENTINE RA, CONEYWORTH LJ, MATHERS JC and FORD D, 2008. Mechanisms of mammalian zinc-regulated gene expression. Biochemical society transactions. 36(Pt 6), 1262-6