Brameld, John - University of Nottingham

研究领域

My Research interests are predominantly the study of interactions between hormones and nutrients in the regulation of growth, development and metabolism, particularly of liver, skeletal muscle and adipose tissue.

近期论文

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LEWIS JE, BRAMELD JM, HILL P, WILSON, D, BARRETT P, EBLING FJP and JETHWA PH, 2016. Thyroid hormone and vitamin D regulate VGF expression and promoter activity. Journal of Molecular Endocrinology. 56(2), 123-134 BROWN, DM, WILLIAMS, H, RYAN, KJP, WILSON, TL, DANIEL, ZCTR, MAREKO, MHD, EMES, RD, HARRIS, DW, JONES, S, WATTIS, JAD, DRYDEN, IL, HODGMAN, TC, BRAMELD, JM & PARR, T, 2016. Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth. Scientific Reports. 6, 28693 PARR T, MAREKO MH, RYAN KJ, HEMMINGS KM, BROWN DM and BRAMELD JM, 2016. The impact of growth promoters on muscle growth and the potential consequences for meat quality. Meat science. 120, 93-9 2016. Epigenetics and developmental programming of welfare and production traits in farm animals. Reproduction, fertility, and development. (In Press.) BRAMELD, JOHN M. and PARR, TIM, 2016. Improving efficiency in meat production PROCEEDINGS OF THE NUTRITION SOCIETY. 75(3), 242-246 LEWIS JE, BRAMELD JM and JETHWA PH, 2015. Neuroendocrine Role for VGF. Frontiers in endocrinology. 6, 3 HEMMINGS, K. M., DANIEL, Z. C. T. R., BUTTERY, P. J., PARR, T. and BRAMELD, J. M., 2015. Differential effects of short-term beta agonist and growth hormone treatments on expression of myosin heavy chain IIB and associated metabolic genes in sheep muscle ANIMAL. 9(2), 285-294 LEWIS JE, BRAMELD JM, HILL P, BARRETT P, EBLING FJP and JETHWA PH, 2015. The use of a viral 2A sequence for the simultaneous over-expression of both the vgf gene and enhanced green fluorescent protein (eGFP) in vitro and in vivo. Journal of neuroscience methods. 256, 22-29 MAY, K., O'SULLIVAN, S. E., BRAMELD, J. M., O'NEILL, H. V. MASEY, PARR, T. and WISEMAN, J., 2015. Xylanase supplementation in feed reduces incretin and PYY levels in piglets PROCEEDINGS OF THE NUTRITION SOCIETY. 74(OCE5), E294-E294 AL-HARBI, L., BRAMELD, J. M. and PARR, T., 2015. The active form of vitamin D, Calcitriol, induces vasodilation in the rat aorta PROCEEDINGS OF THE NUTRITION SOCIETY. 74(OCE5), E293-E293 PARR, T., AL-DOSKI, S., HEMMINGS, K., DANIEL, Z., BROWN, D., LU, C., HODGMAN, C., MAY, S. and BRAMELD, J., 2015. Increased expression of serine biosynthetic pathway genes is associated with skeletal muscle hypertrophy in sheep PROCEEDINGS OF THE NUTRITION SOCIETY. 74(OCE2), E183-E183 JING, LU, HOU, YE, WU, HUI, MIAO, YUANXIN, LI, XINYUN, CAO, JIANHUA, BRAMELD, JOHN MICHAEL, PARR, TIM and ZHAO, SHUHONG, 2015. Transcriptome analysis of mRNA and miRNA in skeletal muscle indicates an important network for differential Residual Feed Intake in pigs SCIENTIFIC REPORTS. 5, 11953 BROWN DM, BRAMELD JM and PARR T, 2014. Expression of the myosin heavy chain IIB gene in porcine skeletal muscle: the role of the CArG-Box promoter response element. PloS one. 9(12), e114365 MURPHY, M., SAMMS, R., WARNER, A., BOLBOREA, M., BARRETT, P., FOWLER, M.J., BRAMELD, J.M., TSINTZAS, K., KHARITONENKOV, A., ADAMS, A.C., COSKUN, T. and EBLING, F.J.P., 2013. Increased responses to the actions of fibroblast growth factor 21 on energy balance and body weight in a seasonal model of adiposity Journal of Neuroendocrinology. 25(2), 180-189 RYAN, KJP, DANIEL, ZCTR, CRAGGS, LJL, PARR, T AND BRAMELD, JM, 2013. Dose-dependent effects of Vitamin D on transdifferentiation of muscle to adipose cells.: Conversion of muscle to fat cells by vitamin D Journal of Endocrinology. 217(1), 45-58 MURPHY, M., JETHWA, P.H., WARNER, A., BARRETT, P., NILAWEERA, K.N., BRAMELD, J.M. and EBLING, F.J.P., 2012. Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in Siberian hamsters Endocrinology. 153(1), 101-112 BROWN DM, PARR T and BRAMELD JM, 2012. Myosin Heavy Chain mRNA Isoforms Are Expressed In Two Distinct Cohorts During C2C12 Myogenesis. Journal Of Muscle Research And Cell Motility. 32(6), 383-390 GRAHAM, N.S., MAY, S.T., DANIEL, Z.C.T.R., EMMERSON, Z.F., BRAMELD, J.M. and PARR, T., 2011. Use of the Affymetrix Human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes Animal. 5(6), 861-866 BRAMELD, J M, HOLD, R and BROUGHTON PIPKIN, F, 2011. Regional variation in angiotensin converting enzyme activity in the human placenta. Placenta. 32(11), 906-908 REHFELDT, C, PAS, MFWT, WIMMERS, K, BRAMELD, JM, NISSEN, PM, BERRI, C, VALENTE, LMP, POWER, DM, PICARD, B, STICKLAND, NC and OKSBJERG, N, 2011. Advances In Research On The Prenatal Development Of Skeletal Muscle In Animals In Relation To The Quality Of Muscle-Based Food. I. Regulation Of Myogenesis And Environmental Impact Animal. 5(5), 703-717 REHFELDT, C, PAS, MFWT, WIMMERS, K, BRAMELD, JM, NISSEN, PM, BERRI, C, VALENTE, LMP, POWER, DM, PICARD, B, STICKLAND, NC and OKSBJERG, N, 2011. Advances In Research On The Prenatal Development Of Skeletal Muscle In Animals In Relation To The Quality Of Muscle-Based Food. Ii - Genetic Factors Related To Animal Performance And Advances In Methodology Animal. 5(5), 718-730 NICHOLSON, S.K., TUCKER, G.A. and BRAMELD, J.M., 2010. Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health British Journal of Nutrition. 103(10), 1398-1403 WARNER, A., JETHWA, P.H., WYSE, C.A., I'ANSON, H., BRAMELD, J.M. and EBLING, F.J.P., 2010. Effects of photoperiod on daily locomotor activity, energy expenditure and feeding behavior in a seasonal mammal American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298(5), R1409-R1416 JETHWA, P.H., WARNER, A., FOWLER, M.J., MURPHY, M., DE BACKER, M.W., ADAN, R.A.H., BARRETT, P., BRAMELD, J.M. and EBLING, F.J.P., 2010. Short-days induce weight loss in Siberian hamsters despite overexpression of the agouti-related peptide gene. Journal of Neuroendocrinology. 22(6), 564-575 ZULKIFLI, R.M., PARR, T., SALTER, A.M. and BRAMELD, J.M., 2010. Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols. Journal of Animal Science. 88(8), 2565-75