Alcocer, Marcos - University of Nottingham

个人简介

Associate Professor in Biochemistry 1988-1992 PhD - Biochemistry/Immunology- Institute of Food Research/University of East Anglia, UK. 1986-1988 MSc - Pharmacy and Biochemistry-University of Sao Paulo, Brazil. 1979-1984 BSc - Pharmacy and Biochemistry-University of Sao Paulo, Brazil. 1975-1978 Food Sciences & Technology-Technical degree- Colegio Tecnico Unicamp, Brazil Employment history 2010- Associate Professor - School of Biosciences, University of Nottingham. 2004-2010, Lecturer - School of Biosciences, University of Nottingham. 2000-2004, Senior Research Fellow - School of Biology, University of Nottingham.1997-2000, Research Associate - Institute of Food Research, Norwich. 1995-1996, Lecturer - University of Sao Paulo, Brazil. 1992-1994, Research Associate - Genetics Department, John Innes Institute, Norwich. 1988-1992, PhD Student - Institute of Food Research/University of East Anglia. 1986-1988, MSc Student - University of Sao Paulo, Brazil.1985-1986, QC -Manager - Industrias Reunidas Jaragua, Jaragua, SC, Brazil. 1977-1984, R & D technician - General Foods, Sao Paulo, Brazil.

近期论文

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LIU QM, YANG Y, MALEKI SJ, ALCOCER M, XU SS, SHI CL, CAO MJ and LIU GM, 2016. Anti-Food Allergic Activity of Sulfated Polysaccharide from Gracilaria lemaneiformis is Dependent on Immunosuppression and Inhibition of p38 MAPK. Journal of agricultural and food chemistry. 64(22), 4536-44 DE LA CRUZ S, ALCOCER M, MADRID R, GARCíA A, MARTíN R, GONZáLEZ I and GARCíA T, 2016. Production of in vivo biotinylated scFv specific to almond (Prunus dulcis) proteins by recombinant Pichia pastoris. Journal of biotechnology. 227, 112-9 YANG Y, CAO M, ALCOCER M, LIU Q, FEI D, MAO H and LIU G, 2015. Mapping and characterization of antigenic epitopes of arginine kinase of Scylla paramamosain. Molecular immunology. 65(2), 310-20 FALCONE FH, ALCOCER MJ, OKAMOTO-UCHIDA Y and NAKAMURA R, 2015. Use of humanized rat basophilic leukemia reporter cell lines as a diagnostic tool for detection of allergen-specific IgE in allergic patients: time for a reappraisal? Current allergy and asthma reports. 15(11), 67 MARTI E, WANG X, JAMBARI NN, RHYNER C, OLZHAUSEN J, PéREZ-BAREA JJ, FIGUEREDO GP and ALCOCER MJ, 2015. Novel in vitro diagnosis of equine allergies using a protein array and mathematical modelling approach: a proof of concept using insect bite hypersensitivity. Veterinary immunology and immunopathology. 167(3-4), 171-7 WAN D, WANG X, NAKAMURA R, ALCOCER MJC and FALCONE FH, 2014. Use of Humanized Rat Basophil Leukemia (RBL) Reporter Systems for Detection of Allergen-Specific IgE Sensitization in Human Serum. Methods in molecular biology (Clifton, N.J.). 1192, 177-84 WAN D, LUDOLF F, ALANINE DGW, STRETTON O, ALI ALI E, ET AL., 2014. Use of Humanised Rat Basophilic Leukaemia Cell Line RSATL8 for the Assessment of Allergenicity of Schistosoma mansoni Proteins PLOS neglected tropical diseases. WAN D, LUDOLF F, ALANINE DGW, STRETTON O, ALI ALI E, AL-BARWARY N, WANG X, DOENHOFF MJ, MARI A, FITZSIMMONS CM, DUNNE DW, NAKAMURA R, OLIVEIRA GC, ALCOCER MJC and FALCONE FH, 2014. Use of humanised rat basophilic leukaemia cell line RS-ATL8 for the assessment of allergenicity of Schistosoma mansoni proteins. PLoS neglected tropical diseases. 8(9), e3124 MIROTTI, L., FLORSHEIM, E., RUNDQVIST, L., LARSSON, G., SPINOZZI, F., LEITE-DE-MORAES, M., RUSSO, M. and ALCOCER, M., 2013. Lipids are required for the development of Brazil nut allergy: the role of mouse and human iNKT cells Allergy. 68(1), 74-83 SILVIA DE LA CRUZ, INéS MARíA LóPEZ-CALLEJA, MARCOS ALCOCER, ISABEL GONZALVEZ, ROSARIO MARTIN and TERESA GARCIA, 2013. TaqMan real-time PCR assay for detection of traces of Brazil nut (Bertholletia excelsa) in food products Food Control. (In Press.) WANG X, CATO P, LIN H, LI T, WAN D, ALCOCER MJC and FALCONE FH, 2013. Optimisation and Use of Humanised RBL NF-AT-GFP and NF-AT-DsRed Reporter Cell Lines Suitable for High-Throughput Scale Detection of Allergic Sensitisation in Array Format and Identification of the ECM-Integrin Interaction as Critical Factor. Molecular Biotechnology. DE LA CRUZ S, LóPEZ-CALLEJA IM, ALCOCER M, GONZáLEZ I, MARTíN R and GARCíA T, 2013. Selection of recombinant antibodies by phage display technology and application for detection of allergenic Brazil nut (Bertholletia excelsa) in processed foods. Journal of agricultural and food chemistry. 61(43), 10310-9 WULFERT, F., SANYASI, G., TONGEN, L., WATANABE, L.A., WANG, X., RENAULT, N.K., FALCONE, F.H., JACOB, C.M.A. and ALCOCER, M.J.C., 2012. Prediction of tolerance in children with IgE mediated cow's milk allergy by microarray profiling and chemometric approach Journal of Immunological Methods. 382(1-2), 48–57 RUNDQVIST, L., TENGEL, T., ZDUNEK, J., BJ?RN, E., SCHLEUCHER, J., ALCOCER, M.J.C. and LARSSON, G., 2012. Solution structure, copper binding and backbone dynamics of recombinant Ber e 1–the major allergen from Brazil nut PLoS ONE. 7(10), e46435 RENAULT, N K, GADDIPATI, S R, WULFERT, F, FALCONE, F H, MIROTTI, L, TIGHE, P J, WRIGHT, V and ALCOCER, M J C, 2011. Multiple protein extract microarray for profiling human food-specific immunoglobulins A, M, G and E. Journal of Immunological Methods. 364(1-2), 21-32 WHYTESIDE, G., ALCOCER, M.J.C., KUMITA, J.R., DOBSON, C.M., LAZAROU, M., PLEASS, R.J. and ARCHER, D.B., 2011. Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris PLoS ONE. 6(7), e22692 WHYTESIDE, G, NOR, RM, ALCOCER, MJC and ARCHER, DB, 2011. Activation Of The Unfolded Protein Response In Pichia Pastoris Requires Splicing Of A Hac1 Mrna Intron And Retention Of The C-Terminal Tail Of Hac1p Febs Letters. 585(7), 1037-1041 ALCOCER, M.J.C, RUNQVIST, L and LARSSON, G., 2011. Ber e 1 protein: the versatile major allergen from Brazil nut seeds Biotechnology Letters. KRUSE, S., ZHONG, S., BODI, Z., BUTTON, J., ALCOCER, M.J.C., HAYES, C.J. and FRAY, R., 2011. A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA Scientific Reports. 1, 126 FALCONE, FRANCO H., LIN, JING, RENAULT, NEIL, HAAS, HELMUT, SCHRAMM, GABI, GIBBS, BERNHARD F. and ALCOCER, MARCOS J. C., 2009. The Live Basophil Allergen Array (LBAA): A Pilot Study 2, 153-169 BARNES, SALLY E, ALCOCER, MARCOS J C and ARCHER, DAVID B, 2008. siRNA as a molecular tool for use in Aspergillus niger. Biotechnology Letters. 30(5), 885-90 CHUTRAKUL, CHANIKUL, ALCOCER, MARCOS, BAILEY, KEVIN and PEBERDY, JOHN F, 2008. The production and characterisation of trichotoxin peptaibols, by Trichoderma asperellum. Chemistry & biodiversity. 5(9), 1694-706 HARNETT, M.M., KEAN, D.E., BOITELLE, A., MCGUINESS, S., THALHAMER, T., STEIGER, C.N., EGAN, C., AL-RIYAMI, L., ALCOCER, M.J., HOUSTON, K.M., GRACIE, J.A., MCINNES, I.B. and HARNETT, W., 2008. The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis Annals Of The Rheumatic Diseases. 67(4), 518-523 RENAULT, N, GADDIPATI, S, WULFERT, F, MIROTTI, L, TIGHE, P, WRIGHT, V, LUCAS, J and ALCOCER, M, 2008. Protein microarray profiling of multiple human immunoglobulins against a complete plethora of dietary ingredients In: Annual Congress of the British-Society-of-Immunology. 19-19 MIROTTI, L, GADDIPATI, S, RENAULT, N, MCSHARRY, C, COCHRANE, S and ALCOCER, M, 2008. Natural lipids are essential for Brazil nut allergy in BALB/c mice In: Annual Congress of the British-Society-of-Immunology. 112-112