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个人简介

I obtained my undergraduate degree in veterinary medicine from the University of La Plata, Argentina in 1996 and this was followed by a PhD (Suma Cum Laude) from the University of Munich, Germany in 2001. My first postdoctoral training was done under supervision of Prof. Keith Campbell (2001-2003), and this was followed by a Marie Curie Fellowship (2002-2004). In 2005 I was awarded an RCUK Fellowship (2005-2010). In 2010 I became a Lecturer and in 2015 an Associate Professor in Developmental Epigenetics at the Division of Animal Sciences, School of Biosciences, UoN.

研究领域

The current main research areas in the lab include: Reprogramming somatic cells into a pluripotent state Germ cell development in mammals Stem cells from epiblast stage embryos

近期论文

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SINCLAIR, K. D., RUTHERFORD, K. M. D., WALLACE, J. M., BRAMELD, J. M., STOGER, R., ALBERIO, R., SWEETMAN, D., GARDNER, D. S., PERRY, V. E. A., ADAM, C. L., ASHWORTH, C. J., ROBINSON, J. E. and DWYER, C. M., 2016. Epigenetics and developmental programming of welfare and production traits in farm animals REPRODUCTION FERTILITY AND DEVELOPMENT. 28(10), 1443-1478 AGUERO T, KASSMER S, ALBERIO R, JOHNSON A and KING ML, 2016. Mechanisms of Vertebrate Germ Cell Determination. Advances in experimental medicine and biology. 953, 383-440 GERMAN SD, CAMPBELL KHS, THORNTON E, MCLACHLAN G, SWEETMAN D and ALBERIO R, 2015. Ovine Induced Pluripotent Stem Cells Are Resistant to Reprogramming after Nuclear Transfer. Cellular reprogramming. 17(1), 19-27 GERMAN SD, LEE J, CAMPBELL KH, SWEETMAN D and ALBERIO R, 2015. Actin depolymerization is associated with meiotic acceleration in cycloheximide-treated ovine oocytes. Biology of reproduction. 92(4), 103 JOHNSON AD and ALBERIO R, 2015. Primordial germ cells: the first cell lineage or the last cells standing? Development (Cambridge, England). 142(16), 2730-9 VALDEZ MAGA?A G, RODRíGUEZ A, ZHANG H, WEBB R and ALBERIO R, 2014. Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation. Developmental biology. 387(1), 15-27 ALBERIO R and SINCLAIR KD, 2014. Can we make a placenta in the Petri dish? Reproduction (Cambridge, England). 147(5), E3 ALBERIO R and PEREZ A, 2012. Recent advances in stem and germ cell research: implications for the derivation of pig pluripotent cells. Reproduction in domestic animals = zuchthygiene. 47 Suppl 4, 98-106 RODRíGUEZ, A., ALLEGRUCCI, C. and ALBERIO, R., 2012. Modulation of pluripotency in the porcine embryo and iPS cells PLoS ONE. 7(11), e49079 FREEMAN, T.C., IVENS, A., BAILLIE, J.K., BERALDI, D., BARNETT, M.W., DORWARD, D., DOWNING, A., FAIRBAIRN, L., KAPETANOVIC, R., RAZA, S., TOMOIU, A., ALBERIO, R., WU, C., SU, A.I., SUMMERS, K.M., TUGGLE, C.K., ARCHIBALD, A.L. and HUME, D.A., 2012. A gene expression atlas of the domestic pig BMC Biology. 10, 90 ALLEGRUCCI, C., RUSHTON, M.D., DIXON, J.E., SOTTILE, V., SHAH, M., KUMARI, R., WATSON, S., ALBERIO, R. and JOHNSON, A.D., 2011. Epigenetic reprogramming of breast cancer cells with oocyte extracts Molecular Cancer. 10(1), 7 HYLDIG, S.M.W., CROXALL, N., CONTRERAS, D.A., THOMSEN, P.D. and ALBERIO, .R., 2011. Epigenetic reprogramming in the porcine germ line. BMC Developmental Biology. 11(1), 11 KLISCH, K., CONTRERAS, D.A., SUN, X., BREHM, R., BERGMANN, M. and ALBERIO, R., 2011. The Sda/GM2-glycan is a carbohydrate marker of porcine primordial germ cells and of a subpopulation of spermatogonia in cattle, pigs, horses and llama. Reproduction: The Journal for the Society for Reproduction and Fertility. 142(5), 667-674 DIXON, J.E., ALLEGRUCCI, C., REDWOOD, C., KUMP, K., BIAN, Y., CHATFIELD, J., CHEN, Y.-H., SOTTILE, V., VOSS, S.R., ALBERIO, R. and JOHNSON, A.D., 2010. Axolotl Nanog activity in mouse embryonic stem cells demonstrates that ground state pluripotency is conserved from urodele amphibians to mammals Development. 137(18), 2973-2980 ALBERIO, R., CROXALL, N. and ALLEGRUCCI, C., 2010. Pig epiblast stem cells depend on Activin/Nodal Signaling for pluripotency and self-renewal Stem Cells and Development. 19(10), 1627-36 KELLY R, ALBERIO R and CAMPBELL KHS, 2010. A-type lamin dynamics in bovine somatic cell nuclear transfer embryos Reprod Fertil Devel. 22, 956-965 BIAN, Y., ALBERIO, R., ALLEGRUCCI, C., CAMPBELL, K.H. and JOHNSON, A.D., 2009. Epigenetic marks in somatic chromatin are remodelled to resemble pluripotent nuclei by amphibian oocyte extracts Epigenetics. 4(3), 194-202 MAALOUF, W.E., ALBERIO, R. and CAMPBELL, K.H., 2008. Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos Epigenetics. 3(4), 199-209 BOWLES, EMMA J, LEE, JOON-HEE, ALBERIO, RAMIRO, LLOYD, RHIANNON E I, STEKEL, DOV, CAMPBELL, KEITH H S and ST JOHN, JUSTIN C, 2007. Contrasting effects of in vitro fertilization and nuclear transfer on the expression of mtDNA replication factors. Genetics. 176(3), 1511-26 LLOYD, R.E., LEE, J.-H., ALBERIO, R., BOWLES, E.J., RAMALHO-SANTOS, J., CAMPBELL, K.H.S. and ST JOHN, J.C., 2006. Aberrant nucleo-cytoplasmic cross-talk results in donor cell mtDNA persistence in cloned embryos Genetics. 172(4), 2515-2527 ALBERIO, R., CAMPBELL, K.H. and JOHNSON, A.D., 2006. Reprogramming somatic cells into stem cells Reproduction. 132, 709-720 NICHOLAS, B., ALBERIO, R., FOULADI-NASHTA, A.A. and WEBB, R., 2005. Relationship between low-molecular-weight insulin-like growth factor-binding proteins, caspase-3 activity, and oocyte quality Biology of Reproduction. 72(4), 796-804 ALBERIO, R., JOHNSON, A.D., STICK, R. and CAMPBELL, K.H.S., 2005. Differential nuclear remodeling of mammalian somatic cells by Xenopus laevis oocyte and egg cytoplasm Experimental Cell Research. 307(1), 131-141 FOULADI-NASHTA, A.A., ALBERIO, R., KAFI, M., NICHOLAS, B., CAMPBELL, K.H.S. and WEBB R., 2005. Differential staining combined with TUNEL labelling to detect apoptosis in preimplantation bovine embryos Reproductive BioMedicine Online. 10(4), 497-502 CAMPBELL, K., ALBERIO, R., CHOI, I., FISHER, P., KELLY, R., LEE, J. H. and MAALOUF, W., 2005. Cloning: Eight Years After Dolly Reproduction in Domestic Animals. VOL 40(NUMBER 4), 256-268

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