Pordea, Anca - University of Nottingham - Department of Chemical and Environmental Engineering

个人简介

Anca graduated from the National Institute of Applied Research (INSA) in Rouen (France) in 2004, with a Master Degree in Chemical Engineering focused on the synthesis of fine chemicals. She completed her PhD in Neuchâtel (Switzerland), working on the development of enantioselective catalytic reactions by using artificial metalloenzymes, with Prof. Thomas R. Ward. As a postdoc, she worked on the chemical modification of subtilisin in Oxford (UK) and on the development of organocatalysts in Neuchâtel ( Switzerland). She joined the University of Nottingham in 2012 as a lecturer.

近期论文

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PORDEA, ANCA, 2015. Metal-binding promiscuity in artificial metalloenzyme design CURRENT OPINION IN CHEMICAL BIOLOGY. 25, 124-132 WARD TR and PORDEA A, 2012. Enantioselective hybrid catalysts. In: Comprehensive chirality Synthetic methods VI: enzymatic and semi-enzymatic. Elsevier. 516-552 BRUYNEEL F, LETONDOR C, BASTÜRK B, GUALANDI A, PORDEA A, STOECKLI-EVANS H and NEIER R, 2012. Catalytic epoxidation of alkenes by the manganese complex of a reduced porphyrinogen macrocycle Adv. Synth. Cat. 354, 428-440 PORDEA A, STOECKLI-EVANS H, DALVIT C and NEIER R, 2012. Synthesis and reactions of 2-[1-methyl-1-(pyrrolidin-2-yl)ethyl]-1H-pyrrole and some derivatives with aldehydes: chiral structures combining a secondary-amine group with an 1H-pyrrole moiety as excellent H-bond donor Helv. Chim. Acta. 95, 2249-2264 KÖHLER V, MAO J, HEINISCH T, PORDEA A, SARDO A, WILSON YM, KNÖRR L, CREUS M, PROST JC, SCHIRMER T and WARD TR, 2011. OsO4⋅streptavidin: A tunable hybrid catalyst for the enantioselective cis-dihydroxylation of olefins Angew. Chem. Int. Ed. 50, 10863-10866 PORDEA A, CREUS M, LETONDOR C, IVANOVA A and WARD TR, 2010. Improving the enantioselectivity of artificial transfer hydrogenases based on the biotin-streptavidin technology by combinations of point mutations Inorg. Chim. Acta. 363, 601-604 PORDEA A, MATHIS D and WARD TR, 2009. Incorporation of biotinylated manganese-salen complexes into streptavidin: new artificial metalloenzymes for enantioselective sulfoxidation J. Organomet. Chem. 694, 930-936 PORDEA A and WARD TR, 2009. Artificial metalloenzymes: combining the best features of homogeneous and enzymatic catalysis Synlett. 20, 3225-3236 CREUS, M., PORDEA, A., ROSSEL, T., SARDO, A., LETONDOR, C., IVANOVA, A., LETRONG, I., STENKAMP, R.E. and WARD, T.R., 2008. X-ray structure and designed evolution of an artificial transfer hydrogenase Angewandte Chemie International Edition. 47(8), 1400-1404 PORDEA A, CREUS M, PANEK J, DUBOC C, MATHIS D, NOVIC M and WARD TR, 2008. Artificial metalloenzyme for enantioselective sulfoxidation based on vanadyl-loaded streptavidin J. Am. Chem. Soc. 130, 8085-8088 PORDEA A, 2008. Chemogenetic protein engineering: an efficient tool for the optimization of artificial metalloenzymes Chem. Commun. 4239-4249 LETONDOR C, PORDEA A, HUMBERT N, IVANOVA A, MAZUREK S, NOVIC M and WARD TR, 2006. Artificial transfer-hydrogenases based on the biotin-(strept)avidin technology: fine tuning the selectivity by saturation mutagenesis of the host protein J. Am. Chem. Soc. 128, 8320-8328