个人简介
Anna obtained her BSc degree, majoring in Chemistry and Biochemistry, from the University of Adelaide, Australia. After completing an honours degree in Organic Chemistry at the same institution, she went on to complete her PhD at the Australian National University looking at the processes governing formation of free radicals in proteins.
She subsequently completed a European union-funded postdoctoral fellowship at the University of Newcastle upon Tyne, examining the chemistry of coenzyme B12-dependent enzymes, and was then offered a full academic post at the University of Wales Bangor, where she established her own research group. She was promoted to Senior Lecturer there in 2011.
In 2013 she joined the Bioprocessing and Biorenewables group at the University of Nottingham, where she has established her own Biomechanism Engineering research team. The focus of the team is to understand how biological processes can be used as templates to improve chemical reactivity and, similarly, how an understanding of chemical reactivity can be used to direct biomolecule reactions for specific outputs (such as production of high-value chemicals and feedstocks from biorenewables).
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ESHTAYA, M., EJIGU, A., STEPHENS, G., WALSH, D. A., CHEN, G. Z.* and CROFT, A. K.*, 2016. Developing energy efficient lignin biomass processing – Towards understanding mediator behaviour in ionic liquids FARADAY DISCUSSIONS: Liquid Salts for Energy and Materials. 190, 127-145
GUNASEKERA, D. H. A. T., KUEK, S., HASANAJ, D., HE, Y., TUCK, C., CROFT, A. K. and WILDMAN, R. D., 2016. Three dimensional ink-jet printing of biomaterials using ionic liquids and co-solvents Faraday Discussions. 190, 509-523
DANIEL P. DOWLING, YAN KUNG, ANNA K. CROFT, KOLI TAGHIZADEH, WENDY L. KELLY, CHRISTOPHER T. WALSH and CATHERINE L. DRENNAN, 2016. Structural elements of an NRPS cyclization domain and its intermodule docking domain Proceedings of the National Academy of Sciences of the United States of America.
JAGER, CHRISTOF MARTIN and CROFT, ANNA KRISTINA, 2016. Radical Reaction Control in the AdoMet Radical Enzyme CDG Synthase (QueE): Consolidate, Destabilize, Accelerate. Chemistry (Weinheim an der Bergstrasse, Germany): A European Journal. 22,
MARYAM KARIMI, MARTA T. IGNASIAK, BUN CHAN, ANNA K. CROFT, LEO RADOM, CARL H. SCHIESSER and DAVID I. PATTISON, 2016. Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability Scientific Reports. 38572
KEAVENEY, S. T., HARPER, J. B. and CROFT, A. K., 2015. Computational approaches to understanding reaction outcomes of organic processes in ionic liquids RSC Advances. 5(45), 35709-35729
GROENEWALD W., BAIRD M.S., VERSCHOOR J.A., MINNIKIN D.E., CROFT A.K., 2014. Differential spontaneous folding of mycolic acids from Mycobacterium tuberculosis Chemistry and Physics of Lipids. 180, 15–22
TIERNEY, MS, SOLER-VILA, A, RAI, DK, CROFT, AK and BRUNTON, NP, 2014. UPLC-MS profiling of low molecular weight phlorotannin polymers in Ascophyllum nodosum, Pelvetia canaliculata and Fucus spiralis Metabolomics. 10(3), 524-535
TIERNEY, MICHELLE S., SMYTH, THOMAS J., RAI, DILIP K., SOLER-VILA, ANNA, CROFT, ANNA K. and BRUNTON, NIGEL, 2013. Enrichment of polyphenol contents and antioxidant activities of Irish brown macroalgae using food-friendly techniques based on polarity and molecular size Food Chemistry. 139(1-4), 753-761
H. M. YAU, S. T. KEAVENEY, B. J. BUTLER, E. E. L. TANNER, M. S. GUERRY, S. R. D. GEORGE, M. H. DUNN, A. K. CROFT and J. B. HARPER, 2013. Towards solvent-controlled reactivity in ionic liquids Pure and Applied Chemistry. 85(10), 1979–1990
M. S. TIERNEY, A. SOLER-VILA, A. K. CROFT and M. HAYES, 2013. Antioxidant Activity of the Brown Macroalgae Fucus spiralis Linnaeus Harvested from the West Coast of Ireland Current Research Journal of Biological Sciences. 5(3), 81-90
H. M. YAU and A. K. CROFT, 2013. Reaction mechanisms: polar reactions Annu. Rep. Prog. Chem., Sect. B. 109, 275-294
TANNER EEL, YAU HM, HAWKER RR, CROFT AK and HARPER JB, 2013. Does the cation really matter? The effect of modifying an ionic liquid cation on an SN2 process. Organic & biomolecular chemistry. 11(36), 6170-5
TIERNEY, MICHELLE S., SOLER-VILA, ANNA, RAI, DILIP K., CROFT, ANNA K., BRUNTON, NIGEL P. and SMYTH, THOMAS J., 2013. UPLC-MS profiling of low molecular weight phlorotannin polymers in Ascophyllum nodosum, Pelvetia canaliculata and Fucus spiralis Metabolomics.
TANNER E.E.L., HAWKER R.R., YAU H.M., CROFT A.K., HARPER J.B., 2013. Probing the importance of ionic liquid structure: A general ionic liquid effect on an SNAr process Organic & Biomolecular Chemistry.
DOWLING, DANIEL P., VEY, JESSICA L., CROFT, ANNA K. and DRENNAN, CATHERINE L., 2012. Structural diversity in the AdoMet radical enzyme superfamily Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1824(11), 1178-1195
CROFT, ANNA K., GROENEWALD, WILMA and TIERNEY, MICHELLE S., 2012. Medicinal Chemistry and Ligand Profiling for Evaluation of Promising Bioactive Molecules. In: HAYES, MARIA, ed., Marine Bioactive Compounds: Characterization and Applications Springer-Link. 173-206
DOWLING, D. P., CROFT, A. K. and DRENNAN, C. L., 2012. Radical Use of Rossmann and TIM Barrel Architectures for Controlling Coenzyme B-12 Chemistry: Annual Review of Biophysics, Vol 41 Annual Review of Biophysics, Vol 41. 41, 403-427
DOWLING, D. P., VEY, J. L., CROFT, A. K. and DRENNAN, C. L., 2012. Structural diversity in the AdoMet radical enzyme superfamily: Biochimica Et Biophysica Acta-Proteins and Proteomics Biochimica Et Biophysica Acta-Proteins and Proteomics. 1824(11), 1178-1195
YAU, H. M. and CROFT, A. K., 2012. Reaction mechanisms: polar reactions: Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, Vol 108 Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, Vol 108. 108, 272-291
YAU, H. M., CROFT, A. K. and HARPER, J. B., 2012. Investigating the origin of entropy-derived rate accelerations in ionic liquids: Faraday Discussions Faraday Discussions. 154, 365-371
YAU, H. M., CROFT, A. K. and HARPER, J. B., 2012. 'One-pot' Hammett plots: a general method for the rapid acquisition of relative rate data: Chemical Communications Chemical Communications. 48(71), 8937-8939
CADMAN, C. J. and CROFT, A. K., 2011. Anion-pi interactions influence pK(a) values: Beilstein Journal of Organic Chemistry Beilstein Journal of Organic Chemistry. 7, 320-328
CROFT, A. K. and DAVIES, E., 2011. Reaction mechanisms: polar reactions: Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, Vol 107 Annual Reports on the Progress of Chemistry, Section B: Organic Chemistry, Vol 107. 107, 287-307
CROFT, A. K., HOWARD-JONES, H. M., SKATES, C. E. and WOOD, C. C., 2011. Controlling the action of chlorine radical: from lab to environment: Organic & Biomolecular Chemistry Organic & Biomolecular Chemistry. 9(21), 7439-7447
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