O'Reilly, Elaine - University of Nottingham

个人简介

Elaine O'Reilly graduated from University College Dublin (UCD) with a Bsc (Hons) in Chemistry (2006) and began a PhD in organic chemistry at UCD. In 2010, she moved to The University of Manchester where she spent four years working as a Postdoctoral Research Fellow under the direction of Prof. Nicholas J. Turner. In 2014, she joined Manchester Metropolitan University as a Lecturer in Chemical Biology. In February 2015, she was appointed Assistant Professor in Chemical Biology at the School of Chemistry, University of Nottingham where her research focuses on the development and application of biocatalysts. There are PhD opportunities available for 2016 so please contact me for details.

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ELAINE O'REILLY and NICHOLAS J. TURNER, 2016. In: JOHN WHITTALL, PETER SUTTON and WOLFGANG KROUTIL,, eds., Practical Methods in Biocatalysis: ω-Transaminase/Monoamine Oxidase Cascade for the Regio- and Stereoselective Synthesis of Chiral 2,5-Disubstituted Pyrrolidines Wiley. ANDREW GOMM, WILLIAM LEWIS, ANTHONY P. GREEN and ELAINE O'REILLY, 2016. A New Generation of Smart Amine Donors for Transaminase-Mediated Biotransformations Chemistry: A European Journal. ELAINE O'REILLY and NICHOLAS J. TURNER, 2015. Enzymatic Cascades for the Regio- and Stereoselective Synthesis of Chiral Amines Perspectives in Science. 4, 55-61 GREEN AP, TURNER NJ and O'REILLY E, 2014. Chiral amine synthesis using ω-transaminases: an amine donor that displaces equilibria and enables high-throughput screening.: (Very Important Paper) Angewandte Chemie (International ed. in English). 53(40), 10714-7 O'REILLY E, IGLESIAS C, GHISLIERI D, HOPWOOD J, GALMAN JL, LLOYD RC and TURNER NJ, 2014. A regio- and stereoselective ω-transaminase/monoamine oxidase cascade for the synthesis of chiral 2,5-disubstituted pyrrolidines. Angewandte Chemie (International ed. in English). 53(9), 2447-50 ELAINE O'REILLY and CESAR IGLESIAS, 2014. Monoamine Oxidase/ ω-Transaminase Cascade for the Deracemisation and Dealkylation of Amines ChemcatChem. 6, 992-995 TURNER NJ and O'REILLY E, 2013. Biocatalytic retrosynthesis. Nature chemical biology. 9(5), 285-8 O'REILLY E, PES L, ORTIN Y, MÜLLER-BUNZ H and PARADISI F, 2013. Synthesis of a conformationally constrained δ-amino acid building block. Amino acids. 44(2), 511-8 ELAINE O'REILLY, MARK CORBETT, SHAHED HUSSAIN, PAUL P. KELLY, DOMINIQUE RICHARDSON and SABINE L. FLITSCH, 2013. Substrate promiscuity of cytochrome P450 RhF Catalysis Science & Technology. 3, 1490-1492 O'REILLY E, AITKEN SJ, GROGAN G, KELLY PP, TURNER NJ and FLITSCH SL, 2012. Regio- and stereoselective oxidation of unactivated C-H bonds with Rhodococcus rhodochrous. Beilstein journal of organic chemistry. 8, 496-500 O'REILLY, ELAINE, KOEHLER, VALENTIN, FLITSCH, SABINE L. and TURNER, NICHOLAS J., 2011. Cytochromes P450 as useful biocatalysts: addressing the limitations CHEMICAL COMMUNICATIONS. 47(9), 2490-2501 ROBIN, AELIG, KOEHLER, VALENTIN, JONES, ALISON, ALI, AFRUJA, KELLY, PAUL P., O'REILLY, ELAINE, TURNER, NICHOLAS J. and FLITSCH, SABINE L., 2011. Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. 7, 1494-1498 O'REILLY E, BALDUCCI D and PARADISI F, 2010. A stereoselective synthesis of alpha-deuterium-labelled (S)-alpha-amino acids. Amino acids. 39(3), 849-58 O'REILLY, ELAINE, PES, LARA and PARADISI, FRANCESCA, 2010. From amines to diketopiperazines: a one-pot approach TETRAHEDRON LETTERS. 51(13), 1696-1697 O'REILLY, ELAINE, LESTINI, ELENA, BAIDUCCI, DANIELE and PARADISI, FRANCESCA, 2009. One-step diketopiperazine synthesis using phase transfer catalysis TETRAHEDRON LETTERS. 50(15), 1748-1750