个人简介
Education:
University of Bath, 2001, MChem (1st class hons)
University of Oxford, DPhil 2004 (Sir Jack Baldwin)
SCRIPPS, PDRA 2005 (K. Barry Sharpless)
John's independent academic research career began at The University of London, School of Pharmacy in 2005, where he was appointed as an RCUK-EPSRC academic fellow in Chemical Biology/Cancer Medicinal Chemistry. In September 2007, he was appointed tat the University of Nottingham as an Associate Professor in Organic Chemistry. In 2011 he was promoted to Reader in Chemical Biology.
近期论文
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BHAT, SHREESHA V., ROBINSON, DAVID, MOSES, JOHN E. and SHARMA, PALLAVI, 2016. Synthesis of Oxadiazol-5-imines via the Cyclizative Capture of in Situ Generated Cyanamide Ions and Nitrile Oxides ORGANIC LETTERS. 18(5), 1100-1103
ZHANG E, TANG J, LI S, WU P, MOSES JE and SHARPLESS KB, 2016. Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates. Chemistry (Weinheim an der Bergstrasse, Germany). 22(16), 5692-7
STANLEY PA, SPITERI C, MOORE JC, BARROW AS, SHARMA P and MOSES JE, 2016. Biomimetic Approaches Towards The Synthesis of Complex Dimeric Natural Products. Current pharmaceutical design. 22(12), 1628-57
BHAT SV, ROBINSON D, MOSES JE and SHARMA P, 2016. Synthesis of Oxadiazol-5-imines via the Cyclizative Capture of in Situ Generated Cyanamide Ions and Nitrile Oxides. Organic letters. 18(5), 1100-3
ROE S, GUNARATNAM M, SPITERI C, SHARMA P, ALHARTHY RD, NEIDLE S and MOSES JE, 2015. Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Organic & biomolecular chemistry. 13(31), 8500-4
DEMPSTER S, HARPER S, MOSES JE and DREVENY I, 2014. Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta crystallographica. Section D, Biological crystallography. 70(Pt 5), 1484-90
COUSINS AR, RITSON D, SHARMA P, STEVENS MF, MOSES JE and SEARLE MS, 2014. Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences. Chemical communications (Cambridge, England). 50(96), 15202-5
MOORE JC, DAVIES ES, WALSH DA, SHARMA P and MOSES JE, 2014. Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels-Alder reaction. Chemical communications (Cambridge, England). 50(83), 12523-5
POWELL KJ, HAN LC, SHARMA P and MOSES JE, 2014. Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic letters. 16(8), 2158-61
BORREGUERO, ANA M., SHARMA, PALLAVI, SPITERI, CHRISTIAN, VELENCOSO, MARIA M., CARMONA, MANUEL S., MOSES, JOHN E. and RODRIGUEZ, JUAN F., 2013. A novel click-chemistry approach to flame retardant polyurethanes REACTIVE & FUNCTIONAL POLYMERS. 73(9), 1207-1212
CARBONE, GIORGIO, BURNLEY, JAMES and MOSES, JOHN E., 2013. A catalytic and tert-butoxide ion-mediated amidation of aldehydes with para-nitro azides CHEMICAL COMMUNICATIONS. 49(27), 2759-2761
BURNLEY, JAMES, CARBONE, GIORGIO and MOSES, JOHN E., 2013. Catalytic Reduction of ortho- and para-Azidonitrobenzenes via tert-Butoxide Ion Mediated Electron Transfer SYNLETT. 24(5), 652-656
POWELL, KIMBERLEY J., SHARMA, PALLAVI, RICHENS, JOANNA L., DAVIS, BENJAMIN M., MOSES, JOHN E. and O'SHEA, PAUL, 2012. Interactions of marine-derived gamma-pyrone natural products with phospholipid membranes PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 14(42), 14489-14491
SPITERI, CHRISTIAN and MOSES, JOHN E., 2012. Continuous Flow Synthesis of Secondary Amides by Tandem Azidation-Amidation of Anilines SYNLETT. 1546-1548
MOORHOUSE, A.D., SPITERI, C., SHARMA, P., ZLOH, M. and MOSES, J.E., 2011. Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5 Chemical Communications. 47(1), 230-232
SHARMA, P., RITSON, D.J., BURNLEY, J. and MOSES, J.E., 2011. A synthetic approach to kingianin A based on biosynthetic speculation Chemical Communications. 47(38), 10605-10607
AWAAD AS, AL-JABER NA, SOLIMAN GA, AL-OUTHMAN MR, ZAIN ME, MOSES JE and EL-MELIGY RM, 2011. New Biological Activities Of Casimiroa Edulis Leaf Extract And Isolated Compounds. Phytotherapy Research : Ptr. (In Press.)
RITSON DJ, SPITERI C and MOSES JE, 2011. A Silver-Mediated One-Step Synthesis Of Oxazoles. The Journal Of Organic Chemistry. 76(9), 3519-22
SHARMA, PALLAVI, RITSON, DOUGAL J., BURNLEY, JAMES and MOSES, JOHN E., 2011. A synthetic approach to kingianin A based on biosynthetic speculation CHEMICAL COMMUNICATIONS. 47(38), 10605-10607
SPITERI, CHRISTIAN, BURNLEY, JAMES and MOSES, JOHN E., 2011. Catalyst-Free Regioselective Hydrostannation of Arynes SYNLETT. 2533-2536
SPITERI C, KEELING S and MOSES JE, 2010. New Synthesis Of 1-Substituted-1H-Indazoles Via 1,3-Dipolar Cycloaddition Of In Situ Generated Nitrile Imines And Benzyne. Organic Letters. 12(15), 3368-71
SHARMA P and MOSES JE, 2010. Ethynyldiisopropylsilyl: A New Alkynylsilane Protecting Group And "Click" Linker. Organic Letters. 12(12), 2860-3
ROE S, RITSON DJ, GARNER T, SEARLE M and MOSES JE, 2010. Tuneable Dna-Based Asymmetric Catalysis Using A G-Quadruplex Supramolecular Assembly. Chemical Communications (Cambridge, England). 46(24), 4309-11
LOMBARDO CM, MARTíNEZ IS, HAIDER S, GABELICA V, DE PAUW E, MOSES JE and NEIDLE S, 2010. Structure-Based Design Of Selective High-Affinity Telomeric Quadruplex-Binding Ligands. Chemical Communications (Cambridge, England). 46(48), 9116-8
MOSES JE, RITSON DJ, ZHANG F, LOMBARDO CM, HAIDER S, OLDHAM N and NEIDLE S, 2010. A Click Chemistry Approach To C3 Symmetric, G-Quadruplex Stabilising Ligands. Organic & Biomolecular Chemistry. 8(13), 2926-30