Moody, Chris - University of Nottingham

个人简介

Chris Moody is Sir Jesse Boot Professor of Chemistry and Head of Organic Chemistry at the University of Nottingham. He is a Mancunian and was educated at Manchester Grammar School and King's College, London, before carrying out his PhD research at the University of Liverpool under the supervision of Charles Rees investigating the synthesis and reactions of nitrogen-sulfur ylides. He spent a postdoctoral year at the ETH in Zürich working with Albert Eschenmoser on the stereochemistry of 1,4-elimination reactions before taking up a post in industry at Roche. In 1979 he was appointed to a lectureship at Imperial College, London, and was promoted to a readership in 1989. In 1990 moved to the chair of organic chemistry at Loughborough University, and in 1996 he was appointed Professor of Organic Chemistry at the University of Exeter. He moved to his current post in Nottingham in August 2005. He has published over 390 papers and his work has been recognised with several awards including the RSC Hickinbottom Fellowship and Corday Morgan Medal (both in 1986), the Tilden Medal and Lectureship (2000-2001), the Adrien Albert Medal and Lectureship (2001), an EPSRC Senior Research Fellowship (2000-2005), the Royal Society of Chemistry Award for Synthetic Organic Chemistry (2006), the Pedler Lectureship (2008), the Novartis International Lectureship (2010-2011), and the Royal Society of Chemistry Charles Rees Award (2012).

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BLUNT, CHRISTOPHER E., NAWRAT, CHRISTOPHER C., LEBOZEC, LUCILLE, LIUTKUS, MANTAS, LIU, YANG, LEWIS, WILLIAM and MOODY, CHRISTOPHER J., 2016. Oxidative Routes to the Heterocyclic Cores of Benzothiazole Natural Products SYNLETT. 27(1), 37-40 PATEL, ALPA, SHARP, SWEE Y., HALL, KATELAN, LEWIS, WILLIAM, STEVENS, MALCOLM F. G., WORKMAN, PAUL and MOODY, CHRISTOPHER J., 2016. Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines ORGANIC & BIOMOLECULAR CHEMISTRY. 14(16), 3889-3905 NICOLLE, SIMON M., LEWIS, WILLIAM, HAYES, CHRISTOPHER J. and MOODY, CHRISTOPHER J., 2016. Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N-H Insertion Reaction of Metallocarbenes with -Aminoketone Derivatives: Angewandte Chemie-International Edition Angewandte Chemie-International Edition. 55(11), 3749-3753 D. M. RAMSEY, R. R. A. KITSON, J. I. LEVIN, C. J. MOODY and S. R. MCALPINE, 2015. Recent advances in macrocyclic Hsp90 inhibitors. In: Macrocycles in Drug Discovery Royal Society of Chemistr. 37-77 MULAS A, WILLENER Y, CARR-SMITH J, JOLY KM, MALE L, MOODY CJ, HORSWELL SL, NGUYEN HV and TUCKER JHR, 2015. The effect of central and planar chirality on the electrochemical and chiral sensing properties of ferrocenyl urea H-bonding receptors. Dalton Transactions. 44(16), 7268-75 NICOLLE SM, HAYES CJ and MOODY CJ, 2015. Alkyl halide-free heteroatom alkylation and epoxidation facilitated by a recyclable polymer-supported oxidant for the in-flow preparation of diazo compounds. Chemistry a European Journal. 21(12), 4576-9 NORTCLIFFE A and MOODY CJ, 2015. Seven-membered ring scaffolds for drug discovery: Access to functionalised azepanes and oxepanes through diazocarbonyl chemistry. Bioorganic & medicinal chemistry. 23(11), 2730-5 BLUNT CE, TORCUK C, LIU Y, LEWIS W, SIEGEL D, ROSS D and MOODY CJ, 2015. Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity. Angewandte Chemie (International ed. in English). 54(30), 8740-5 NICOLLE SM, LEWIS W, HAYES CJ and MOODY CJ, 2015. Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene O?H Insertion Reaction. Angewandte Chemie (International ed. in English). 54(29), 8485-9 PATEL, ALPA, LEWIS, WILLIAM, SEARLE, MARK S., STEVENS, MALCOLM F. G. and MOODY, CHRISTOPHER J., 2015. Synthesis of 6-arylisocytosines and their potential for hydrogen bonding interactions TETRAHEDRON. 71(39), 7339-7343 MOODY, CJ, 2015. Charles Wayne Rees CBE Biographical Memoirs of Fellows of the Royal Society. 61, 351-378 WADA, HIROKI, WILLIAMS, HUW E. L. and MOODY, CHRISTOPHER J., 2015. Total Synthesis of the Posttranslationally Modified Polyazole Peptide Antibiotic Plantazolicin A ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 54(50), 15147-15151 XIONG, RUI, ZHOU, WENBO, SIEGEL, DAVID, KITSON, RUSSELL R. A., FREED, CURT R., MOODY, CHRISTOPHER J. and ROSS, DAVID, 2015. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T alpha-Synuclein Toxicity: Molecular Pharmacology Molecular Pharmacology. 88(6), 1045-1054 DUTTON BL, KITSON RRA, PARRY-MORRIS S, ROE SM, PRODROMOU C and MOODY CJ, 2014. Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90. Organic & biomolecular chemistry. 12(8), 1328-40 VISCONTI, ANDREA and MOODY, CHRISTOPHER J., 2014. TWO-DIRECTIONAL SYNTHESIS OF 2,6-DIMETHYLPYRROLO-[2,3-f]INDOLE-4,8-DIONE BY DOUBLE CLAISEN REARRANGEMENT AND NITRENE CYCLIZATION HETEROCYCLES. 88(1), 705-710 NICOLLE, SIMON M. and MOODY, CHRISTOPHER J., 2014. Potassium N-Iodo p-Toluenesulfonamide (TsNIK, Iodamine-T): A New Reagent for the Oxidation of Hydrazones to Diazo Compounds CHEMISTRY-A EUROPEAN JOURNAL. 20(15), 4420-4425 NAWRAT, CHRISTOPHER C. and MOODY, CHRISTOPHER J., 2014. Quinones as Dienophiles in the Diels-Alder Reaction: History and Applications in Total Synthesis ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 53(8), 2056-2077 ANDERSON I, LOW JS, WESTON S, WEINBERGER M, ZHYVOLOUP A, LABOKHA AA, CORAZZA G, KITSON RA, MOODY CJ, MARCELLO A and FASSATI A, 2014. Heat shock protein 90 controls HIV-1 reactivation from latency. Proceedings of the National Academy of Sciences of the United States of America. 111(15), E1528-37 CHANG C, DRECHSEL DA, KITSON RRA, SIEGEL D, YOU Q, BACKOS DS, JU C, MOODY CJ and ROSS D, 2014. 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity. Molecular pharmacology. 85(6), 849-57 NAWRAT CC, KITSON RRA and MOODY CJ, 2014. Toward the total synthesis of hygrocin B and divergolide C: construction of the naphthoquinone-azepinone core. Organic letters. 16(7), 1896-9 CARVALHO C, SIEGEL D, INMAN M, XIONG R, ROSS D and MOODY CJ, 2014. Benzofuranquinones as inhibitors of indoleamine 2,3-dioxygenase (IDO). Synthesis and biological evaluation. Organic & biomolecular chemistry. 12(17), 2663-74 JOLIBOIS AER, LEWIS W and MOODY CJ, 2014. Total synthesis of (±)-distomadines A and B. Organic letters. 16(4), 1064-7 GIALLOMBARDO, DANIELE, NEVIN, ADAM C., LEWIS, WILLIAM, NAWRAT, CHRISTOPHER C., KITSON, RUSSELL R. A. and MOODY, CHRISTOPHER J., 2014. Synthesis of toxyloxanthone B TETRAHEDRON. 70(6), 1283-1288 MITCHELL LJ and MOODY CJ, 2014. Solar photochemical oxidation of alcohols using catalytic hydroquinone and copper nanoparticles under oxygen: oxidative cleavage of lignin models. The Journal of organic chemistry. 79(22), 11091-100 WALSH K, SNEDDON HF and MOODY CJ, 2014. Solar photochemical oxidations of benzylic and allylic alcohols using catalytic organo-oxidation with DDQ: application to lignin models. Organic letters. 16(19), 5224-7