Lam, Hon Wai - University of Nottingham

个人简介

Hon Wai Lam was born in Harrow, England in 1976, and grew up in northwest London. In 1994, Hon moved to the University of Oxford where he received his M.Chem. degree in chemistry in 1998, conducting undergraduate research with Jeremy Robertson. He then moved to the University of Nottingham to carry out his Ph.D studies, working under the direction of Gerald Pattenden. There he completed the total synthesis of the proposed structure of amphidinolide A. In January 2002, Hon moved to Harvard University as a GlaxoSmithKline Postdoctoral Fellow to work with David A. Evans on asymmetric catalysis. In October 2003, Hon joined the School of Chemistry at the University of Edinburgh as a Lecturer, where he started his independent research around the development of new synthetic methodology, enantioselective catalysis, and natural product synthesis. Hon was promoted to Senior Lecturer in 2009, and to Reader in 2012. Recognition of Hon's work has come in the form of an RSC Harrison-Meldola Memorial Prize (2008), the RSC Hickinbottom Award (2011), and an AstraZeneca Excellence in Chemistry Award 2011. Hon took up the GSK Chair of Sustainable Chemistry at the School of Chemistry, University of Nottingham on 1st October 2013.

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MARTINEZ, JOSE I., SMITH, JOSHUA J., HEPBURN, HAMISH B. and LAM, HON WAI, 2016. Chain Walking of Allylrhodium Species Towards Esters During Rhodium-Catalyzed Nucleophilic Allylations of Imines ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 55(3), 1108-1112 SMITH, JOSHUA J., BEST, DANIEL and LAM, HON WAI, 2016. Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines CHEMICAL COMMUNICATIONS. 52(19), 3770-3772 KORKIS, STAMATIS E., BURNS, DAVID J. and LAM, HON WAI, 2016. Rhodium-Catalyzed Oxidative C-H Allylation of Benzamides with 1,3-Dienes by Allyl-to-Allyl 1,4-Rh(III) Migration JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 138(37), 12252-12257 CLARKE, CHRISTOPHER, INCERTI-PRADILLOS, CELIA A. and LAM, HON WAI, 2016. Enantioselective Nickel-Catalyzed anti-Carbometallative Cyclizations of Alkynyl Electrophiles Enabled by Reversible Alkenylnickel E/Z Isomerization JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 138(26), 8068-8071 KHAN, IMTIAZ, CHIDIPUDI, SURESH REDDY and LAM, HON WAI, 2015. Synthesis of spiroindanes by palladium-catalyzed oxidative annulation of non- or weakly activated 1,3-dienes involving C-H functionalization CHEMICAL COMMUNICATIONS. 51(13), 2613-2616 BURNS, ALAN R., MADEC, AMAEL G. E., LOW, DARRYL W., ROY, IAIN D. and LAM, HON WAI, 2015. Enantioselective synthesis of bicyclo[3.n.1]alkanes by chiral phosphoric acid-catalyzed desymmetrizing Michael cyclizations CHEMICAL SCIENCE. 6(6), 3550-3555 CHOI, BONNIE, SAXENAA, AAKARSH, SMITH, JOSHUA J., CHURCHILL, GWYDION H. and LAM, HON WAI, 2015. Enantioselective Copper-Catalyzed Reductive Coupling of Vinylazaarenes with N-Boc Aldimines SYNLETT. 26(3), 350-354 BEST, DANIEL, BURNS, DAVID J. and LAM, HON WAI, 2015. Direct Synthesis of 5-Aryl Barbituric Acids by Rhodium(II)-Catalyzed Reactions of Arenes with Diazo Compounds ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 54(25), 7410-7413 BURNS, DAVID J., BEST, DANIEL, WIECZYSTY, MARTIN D. and LAM, HON WAI, 2015. All-Carbon [3+3] Oxidative Annulations of 1,3-Enynes by Rhodium(III)-Catalyzed C-H Functionalization and 1,4-Migration ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 54(34), 9958-9962 CHIDIPUDI, SURESH REDDY, BURNS, DAVID J., KHAN, IMTIAZ and LAM, HON WAI, 2015. Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed C-H Functionalization and Spiroannulation ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 54(47), 13975-13979 BEST, DANIEL and LAM, HON WAI, 2014. C=N-Containing Azaarenes as Activating Groups in Enantioselective Catalysis JOURNAL OF ORGANIC CHEMISTRY. 79(3), 831-845 ROY, IAIN D., BURNS, ALAN R., PATTISON, GRAHAM, MICHEL, BORIS, PARKER, ALEXANDRA J. and LAM, HON WAI, 2014. A second-generation ligand for the enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylazaarenes CHEMICAL COMMUNICATIONS. 50(22), 2865-2868 LUO, YUNFEI, ROY, IAIN D, MADEC, AMAEL G E and LAM, HON WAI, 2014. Enantioselective synthesis of allylboronates and allylic alcohols by copper-catalyzed 1,6-boration. Angewandte Chemie International Edition. 53(16), 4186-90 PARTRIDGE, BENJAMIN M., GONZALEZ, JORGE SOLANA and LAM, HON WAI, 2014. Iridium-Catalyzed Arylative Cyclization of Alkynones by 1,4-Iridium Migration ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 53(25), 6523-6527 KUJAWA, SZYMON, BEST, DANIEL, BURNS, DAVID J. and LAM, HON WAI, 2014. Synthesis of Spirocyclic Enones by Rhodium-Catalyzed Dearomatizing Oxidative Annulation of 2-Alkenylphenols with Alkynes and Enynes CHEMISTRY-A EUROPEAN JOURNAL. 20(28), 8599-8602 BURNS, DAVID J. and LAM, HON WAI, 2014. Catalytic 1,4-Rhodium(III) Migration Enables 1,3-Enynes to Function as One-Carbon Oxidative Annulation Partners in C-H Functionalizations ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 53(37), 9931-9935 HEPBURN, HAMISH B. and LAM, HON WAI, 2014. The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 53(43), 11605-11610 SIMPSON, ALAIN J. and LAM, HON WAI, 2013. Enantioselective Nickel-Catalyzed Michael Additions of 2-Acetylazaarenes to Nitroalkenes ORGANIC LETTERS. 15(11), 2586-2589 DOOLEY, JOHNATHON D., CHIDIPUDI, SURESH REDDY and LAM, HON WAI, 2013. Catalyst-Controlled Divergent C-H Functionalization of Unsymmetrical 2-Aryl Cyclic 1,3-Dicarbonyl Compounds with Alkynes and Alkenes JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 135(29), 10829-10836 CHIDIPUDI, SURESH REDDY, WIECZYSTY, MARTIN D., KHAN, IMTIAZ and LAM, HON WAI, 2013. Synthesis of Benzopyrans by Pd(II)- or Ru(II)-Catalyzed C-H Alkenylation of 2-Aryl-3-hydroxy-2-cyclohexenones ORGANIC LETTERS. 15(3), 570-573 HEPBURN, HAMISH B., CHOTSAENG, NAWASIT, LUO, YUNFEI and LAM, HON WAI, 2013. Enantioselective Rhodium-Catalyzed Allylation of Cyclic Imines with Potassium Allyltrifluoroborates SYNTHESIS-STUTTGART. 45(19), 2649-2661 SAXENA, A., CHOI, B. and LAM, H.W., 2012. Enantioselective copper-catalyzed reductive coupling of alkenylazaarenes with ketones Journal of the American Chemical Society. 134(20), 8428-8431 CHIDIPUDI, S.R., KHAN, I. and LAM, H.W., 2012. Functionalization of Csp3-H and Csp2-H bonds: synthesis of spiroindenes by enolate-sirected ruthenium-catalyzed oxidative annulation of alkynes with 2-aryl-1,3-dicarbonyl compounds Angewandte Chemie International Edition. 51(48), 12115-12119 LUO, Y., HEPBURN, H.B., CHOTSAENG, N. and LAM, H.W., 2012. Enantioselective rhodium-catalyzed nucleophilic allylation of cyclic imines with allylboron reagents Angewandte Chemie International Edition. 51(33), 8309-8313 LUO, YUNFEI, CARNELL, ANDREW J. and LAM, HON WAI, 2012. Enantioselective Rhodium-Catalyzed Addition of Potassium Alkenyltrifluoroborates to Cyclic Imines ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 51(27), 6762-6766