Hayes, Christopher - University of Nottingham

个人简介

Prof. Christopher Hayes began his academic career here in Nottingham with his B.Sc. in July 1992. Remaining at Nottingham, he completed his Ph.D. studies in organic chemistry, under the supervision of Professor Gerald Pattenden, in September 1995. In January 1996, on a NATO Postdoctoral Fellowship, he moved to the University of California at Berkeley where he worked in the group of Professor Clayton H. Heathcock. In September 1997, he returned to Nottingham as a Lecturer in Organic Chemistry, and has subsequently been promoted to Reader (2003), Associate Professor (2006) and Professor of Organic Chemistry (2011).

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NICOLLE, SIMON M., LEWIS, WILLIAM, HAYES, CHRISTOPHER J. and MOODY, CHRISTOPHER J., 2016. Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N-H Insertion Reaction of Metallocarbenes with -Aminoketone Derivatives: Angewandte Chemie-International Edition Angewandte Chemie-International Edition. 55(11), 3749-3753 BARTON, NAOMI A., MARSH, BENJAMIN J., LEWIS, WILLIAM, NARRAIDOO, NATHALIE, SEYMOUR, GRAHAM B., FRAY, RUPERT and HAYES, CHRISTOPHER J., 2016. Accessing low-oxidation state taxanes: is taxadiene-4(5)-epoxide on the taxol biosynthetic pathway?: Chemical Science Chemical Science. 7(5), 3102-3107 PALFRAMAN, MATTHEW J., ALHARTHY, RIMA D., POWALOWSKA, PAULINA K. and HAYES, CHRISTOPHER J., 2016. Synthesis of triazole-linked morpholino oligonucleotides via Cu-I catalysed cycloaddition: Organic & Biomolecular Chemistry Organic & Biomolecular Chemistry. 14(11), 3112-3119 NICOLLE, SIMON M., HAYES, CHRISTOPHER J. and MOODY, CHRISTOPHER J., 2015. Alkyl Halide-Free Heteroatom Alkylation and Epoxidation Facilitated by a Recyclable Polymer-Supported Oxidant for the In-Flow Preparation of Diazo Compounds: Chemistry-a European Journal Chemistry-a European Journal. 21(12), 4576-4579 NICOLLE, SIMON M., LEWIS, WILLIAM, HAYES, CHRISTOPHER J. and MOODY, CHRISTOPHER J., 2015. Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene O-H Insertion Reaction: Angewandte Chemie-International Edition Angewandte Chemie-International Edition. 54(29), 8485-8489 KETLEY, AMI, CHEN, CATHERINE Z., LI, XIN, ARYA, SUKRAT, ROBINSON, THELMA E., GRANADOS-RIVERON, JAVIER, UDOSEN, INYANG, MORRIS, GLENN E., HOLT, IAN, FURLING, DENIS, CHAOUCH, SORAYA, HAWORTH, BEN, SOUTHALL, NOEL, SHINN, PAUL, ZHENG, WEI, AUSTIN, CHRISTOPHER P., HAYES, CHRISTOPHER J. and BROOK, J. DAVID, 2014. High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines HUMAN MOLECULAR GENETICS. 23(6), 1551-1562 BARTRUM, HANNAH E., BLAKEMORE, DAVID C., MOODY, CHRISTOPHER J. and HAYES, CHRISTOPHER J., 2013. Continuous-flow generation of diazoesters and their direct use in S-H and P-H insertion reactions: synthesis of alpha-sulfanyl, alpha-sulfonyl, and alpha-phosphono carboxylates TETRAHEDRON. 69(10), 2276-2282 MYCOCK, DAVID K., GLOSSOP, PAUL A., LEWIS, WILLIAM and HAYES, CHRISTOPHER J., 2013. A formal synthesis of (+)-lactacystin from 4-hydroxyproline TETRAHEDRON LETTERS. 54(1), 55-57 PLATZ, JAMIE L., MOORE, REBECCA, BROOK, DAVID and HAYES, CHRISTOPHER, 2013. Reversal of RNA toxicity in myotonic dystrophy type 1 using antisense oligonucleotides ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 245, HAYES, CHRISTOPHER J. and SIMPKINS, NIGEL S., 2013. Bridgehead enolate or bridgehead organolithium? DFT calculations provide insights into a difficult bridgehead substitution reaction in the synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) nemorosone ORGANIC & BIOMOLECULAR CHEMISTRY. 11(48), 8458-8462 FRASER, JAMIE, WILSON, LAURA J., BLUNDELL, REBECCA K. and HAYES, CHRISTOPHER J., 2013. Phosphoramidate synthesis via copper-catalysed aerobic oxidative coupling of amines and H-phosphonates CHEMICAL COMMUNICATIONS. 49(79), 8919-8921 BURROUGHS, L, CLARKE, PA, FORINTOS, H, GILKS, JAR, HAYES, CJ, VALE, ME, WADE, W and ZBYTNIEWSKI, M, 2012. Asymmetric Organocatalytic Formation Of Protected And Unprotected Tetroses Under Potentially Prebiotic Conditions Organic & Biomolecular Chemistry. 10(8), 1565-1570 PASCERI R, BARTRUM HE, HAYES CJ and MOODY CJ, 2012. Nucleophilic fluorination of β-ketoester derivatives with HBF4. Chemical communications (Cambridge, England). 48(99), 12077-9 LI, X., ROBINSON, T. E., KETLEY, A., ARYA, S., UDOSEN, I., RIVERON, J. GRANADOS, FURLING, D., HAYES, C. J. and BROOK, J. D., 2012. Observations on oligo-based therapy for Myotonic Dystrophy NEUROMUSCULAR DISORDERS. 22, S27-S27 ARYA, S., LI, X., ROBINSON, T. E., UDOSEN, I., CHEN, C., AUSTIN, C., FURLING, D., HAYES, C., BROOK, J. D. and KETLEY, A., 2012. Compound screening in myotonic dystrophy NEUROMUSCULAR DISORDERS. 22, S29-S29 KRUSE, S., ZHONG, S., BODI, Z., BUTTON, J., ALCOCER, M.J.C., HAYES, C.J. and FRAY, R., 2011. A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA Scientific Reports. 1, 126 BARTRUM, HE, BLAKEMORE, DC, MOODY, CJ and HAYES, CJ, 2011. Rapid Access To Alpha-Alkoxy And Alpha-Amino Acid Derivatives Through Safe Continuous-Flow Generation Of Diazoesters Chemistry-A European Journal. 17(35), 9586-9589 UROOS, M and HAYES, CJ, 2011. Total synthesis of (+)-Cymbodiacetal In: 241st National Meeting and Exposition of the American-Chemical-Society (ACS). - ALHARTHY, RDA and HAYES, CJ, 2011. Procyanidin B3 synthesis: A study of leaving group and Lewis acid activator effects upon interflavan bond formation In: 241st National Meeting and Exposition of the American-Chemical-Society (ACS). - UROOS, M, LEWIS, W, BLAKE, AJ and HAYES, CJ, 2010. Total Synthesis Of (+)-Cymbodiacetal: A Re-Evaluation Of The Biomimetic Route Journal Of Organic Chemistry. 75(24), 8465-8470 BARTRUM, HE, BLAKEMORE, DC, MOODY, CJ and HAYES, CJ, 2010. Synthesis Of Beta-Keto Esters In-Flow And Rapid Access To Substituted Pyrimidines Journal Of Organic Chemistry. 75(24), 8674-8676 UROOS, M and HAYES, CJ, 2010. Synthesis Of The Spirochroman Core Of Dihypoestoxide And Stereochemical Proposal For The Natural Product Organic Letters. 12(22), 5294-5297 BURROUGHS, L, VALE, ME, GILKS, JAR, FORINTOS, H, HAYES, CJ and CLARKE, PA, 2010. Efficient Asymmetric Organocatalytic Formation Of Erythrose And Threose Under Aqueous Conditions Chemical Communications. 46(26), 4776-4778 ALHARTHY, RD and HAYES, CJ, 2010. Procyanidin B3 Synthesis: A Study Of Leaving Group And Lewis Acid Activator Effects Upon Interflavan Bond Formation Tetrahedron Letters. 51(8), 1193-1195 HAMEED, A, BLAKE, AJ and HAYES, CJ, 2010. An Enantioselective Formal Synthesis Of (+)-Lactacystin From Hydroxymethyl Glutamic Acid (Hmg) Synlett. 535-538