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研究领域

My research interest is the immunology of irreversible lung diseases. The features of the inflammatory response and the mediators responsible for these diseases, typified by Chronic Obstructive Pulmonary Disease (COPD), are less well defined than those of reversible lung disease, such as asthma.

近期论文

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BURR SA, WHITTLE J, FAIRCLOUGH LC, COOMBES L and TODD I, 2016. Modifying Hofstee standard setting for assessments that vary in difficulty, and to determine boundaries for different levels of achievement. BMC medical education. 16, 34 SELVARAJAH S, TODD I, TIGHE PJ, JOHN M, BOLTON CE, HARRISON T and FAIRCLOUGH LC, 2016. Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease. Mediators of inflammation. 2016, 3604842 TUBBY C, NEGM OH, HARRISON T, TIGHE PJ, TODD I and FAIRCLOUGH LC, 2016. Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction. The Journal of asthma : official journal of the Association for the Care of Asthma. 0 AYLING K, BOWDEN T, TIGHE P, TODD I, DILNOT EM, NEGM OH, FAIRCLOUGH L and VEDHARA K, 2016. The application of protein microarray assays in psychoneuroimmunology. Brain, behavior, and immunity. TIGHE, P. J., RYDER, R. R., TODD, I. and FAIRCLOUGH, L. C., 2015. ELISA in the multiplex era: potentials and pitfalls: Proteomics Clin Appl Proteomics Clin Appl. 9(3-4), 406-22 GALOZZI, P., NEGM, O., GRECO, E., ALKHATTABI, N., GAVA, A., SFRISO, P., FAIRCLOUGH, L., TODD, I., TIGHE, P. and PUNZI, L., 2015. Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome: Reumatismo Reumatismo. 66(4), 277-84 DAFFA, N. I., TIGHE, P. J., CORNE, J. M., FAIRCLOUGH, L. C. and TODD, I., 2015. Natural and disease-specific autoantibodies in chronic obstructive pulmonary disease: Clin Exp Immunol Clin Exp Immunol. 180(1), 155-63 FAIRCLOUGH LC, STOOP AA, NEGM OH, RADFORD PM, TIGHE PJ and TODD I, 2015. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome. European journal of immunology. 45(10), 2937-44 GALOZZI P, NEGM O, GRECO E, ALKHATTABI N, GAVA A, SFRISO P, FAIRCLOUGH L, TODD I, TIGHE P and PUNZI L, 2015. Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome. Reumatismo. 66(4), 277-84 TIGHE PJ, RYDER RR, TODD I and FAIRCLOUGH LC, 2015. ELISA in the multiplex era: potentials and pitfalls. Proteomics. Clinical applications. 9(3-4), 406-22 DAFFA NI, TIGHE PJ, CORNE JM, FAIRCLOUGH LC and TODD I, 2015. Natural and disease-specific autoantibodies in chronic obstructive pulmonary disease. Clinical and experimental immunology. 180(1), 155-63 SELVARAJAH S, NEGM OH, HAMED MR, TUBBY C, TODD I, TIGHE PJ, HARRISON T and FAIRCLOUGH LC, 2014. Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera. Mediators of inflammation. 2014, 820304 ALOTIBY, A. A., FAIRCLOUGH, L. C., TODD, I. and TIGHE, P. J., 2014. Generation and characterisation of transcription activator-like effector nucleases (TALENs) targeting TNFR1 genome editing IMMUNOLOGY. 143, 95-95 HALALA, R. A., TIGHE, P., TODD, I. and FAIRCLOUGH, L., 2014. Profiling of natural autoantibodies in relation to chronic obstructive pulmonary disease IMMUNOLOGY. 143, 79-79 TARBIAH, N., TIGHE, P., FAIRCLOUGH, L. and TODD, I., 2014. Comparing between smokers and non-smokers immunoglobulin levels and B-cell differentiation IMMUNOLOGY. 143, 81-81 ALBOGAMI, S., NEGM, O., ZANG, L., THOMAS, N., FAIRCLOUGH, L., TODD, I. and TIGHE, P., 2014. The inhibitory effects of recombinant PLAD wild type (WT) protein on the inflammatory signalling pathways IMMUNOLOGY. 143, 125-125 HAMED, A., TODD, I., TIGHE, P., POWELL, R. and FAIRCLOUGH, L., 2014. Development of IgE microarray assays for classification of allergic individuals IMMUNOLOGY. 143, 170-170

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