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研究领域

Diabetes Stimulus-secretion coupling and insulin secretion Imidazoline receptors and endogenous ligands Receptor biochemistry and pharmacology Cell signalling

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ALSAQATI, M., LATIF, M. L., CHAN, S. L. F. and RALEVIC, V., 2014. Novel vasocontractile role of the P2Y(14) receptor: characterization of its signalling in porcine isolated pancreatic arteries BRITISH JOURNAL OF PHARMACOLOGY. 171(3), 701-713 ALSAQATI, M., CHAN, S. L. F. and RALEVIC, V., 2014. Investigation of the functional expression of purine and pyrimidine receptors in porcine isolated pancreatic arteries PURINERGIC SIGNALLING. 10(2), 241-249 TAYLOR, J.P., JACKSON, D.A., MORGAN, N.G. and CHAN, S.L. F, 2006. Rhes expression in pancreatic beta-cells is regulated by efaroxan in a calcium-dependent process. Biochemical and Biophysical Research Communications. 349(2), 809-815 PRELL, G. D., MARTINELLI, G. P., HOLSTEIN, G. R., MATULIC-ADAMIC, J., WATANABE, K. A., CHAN, S. L. F., MORGAN, N. G., HAXHIU, M. A. and ERNSBERGER, P., 2004. Imidazoleacetic acid-ribotide: An endogenous ligand that stimulates imidazol(in)e receptors Proceedings of the National Academy of Sciences of the United States of America. 101(37), 13677-13682 BLAND, ROSEMARY, MARKOVIC, DANIJELA, HILLS, CLAIRE E, HUGHES, SUSAN V, CHAN, SUSAN L F, SQUIRES, PAUL E and HEWISON, MARTIN, 2004. Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets. Journal of Steroid Biochemistry and Molecular Biology. 89-90(1-5), 121-5 WANG, M., DUNN, W.R., CHAN, S.L., GARFIELD, B. and WILSON, V.G, 2003. Evidence for nonadrenoceptor responses to imidazoline derivatives in the porcine isolated rectal artery. Annals of the New York Academy of Sciences. 1009, 386-91 CHAN, S.L.F., MONKS, L.K., GAO, H., DEAVILLE, P. and MORGAN, N.G, 2002. Identification of the monomeric G-protein, Rhes, as an efaroxan-regulated protein in the pancreatic beta-cell. British Journal of Pharmacology. 136(1), 31-36 MINYAN, W, . DUNN, W. R., BLAYLOCK, N. A., CHAN, S. L.F. and WILSON, V.G, 2001. Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery. British Journal of Pharmacology. 132(7), 1359-1363 CHAN, S.L.F., MOURTADA, M. and MORGAN, N.G, 2001. Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan. Diabetes. 50(2), 340-7 MORGAN, N. G. and CHAN, S. L. F., 2001. Imidazoline Binding Sites in the Endocrine Pancreas: Can They Fulfil Their Potential as Targets for the Development of New Insulin Secretagogues? Current Pharmaceutical Design. VOL 7(PART 14), 1413-1432 HøY, M, CHAN, S L, WENG, X G and GROMADA, J, 2001. Clonidine-displacing substance reduces glucagon secretion from mouse pancreatic alpha-cells by K(ATP)-channel-independent inhibition of exocytosis. Biochemical and Biophysical Research Communications. 288(2), 309-12

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