Renault, Andrew - University of Nottingham

个人简介

BSc (Biochemistry and Molecular Biology), University of Durham, 1992-1996 with industrial placement at Glaxo Wellcome DPhil (Genetics), University of Oxford, 1996-2001 Postdoctoral researcher, NYU School of Medicine, 2001-2007 under Dr Ruth Lehmann Group leader, Max Planck Institute for Developmental Biology, Tübingen, 2007-2013 Lecturer, School of Life Sciences, University of Nottingham, 2013 - present

研究领域

Our lab is interested in understanding how cellular behaviour is regulated during embryonic development. We use the fruitfly Drosophila melanogaster as our model system and combine genetics, immunohistochemistry, confocal microscopy and live imaging.

近期论文

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HAACK T, SCHNEIDER M, SCHWENDELE B and RENAULT AD, 2014. Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure. Developmental biology. 396(2), 169-82 TRIPATHY R, KUNWAR PS, SANO H and RENAULT AD, 2014. Transcriptional regulation of Drosophila gonad formation. Developmental biology. 392(2), 193-208 ILE, K. E. and RENAULT, A. D., 2013. Compartmentalizing the embryo: lipids and septate junction mediated barrier function Fly. 7(1), 18-22 MUKHERJEE, A., NEHER, R.A. and RENAULT, A.D., 2013. Quantifying the range of a lipid phosphate signal in vivo Journal of Cell Science. n/a(n/a), n/a ANDREW J. MORRIS, SUSAN S. SMYTH, ABDEL K. SALOUS and ANDREW D. RENAULT, 2013. Lipid Phosphate Phosphatases: Recent Progress and Assay Methods. In: JEROLD CHUN, TIMOTHY HLA, SARA SPIEGEL and WOUTER MOOLENAAR, eds., Lysophospholipid Receptors: Signaling and Biochemistry 1. John Wiley & Sons. 229-263 RENAULT, A. D., 2012. vasa is expressed in somatic cells of the embryonic gonad in a sex-specific manner in Drosophila melanogaster Biology Open. 1(10), 1043-8 ILE, K.E., TRIPATHY, R., GOLDFINGER, V. and RENAULT, A.D., 2012. Wunen, a Drosophila lipid phosphate phosphatase, is required for septate junction-mediated barrier function Development. 139(14), 2535-2546 SANO, H., KUNWAR, P. S., RENAULT, A. D., BARBOSA, V., CLARK, I. B., ISHIHARA, S., SUGIMURA, K. and LEHMANN, R., 2012. The Drosophila actin regulator ENABLED regulates cell shape and orientation during gonad morphogenesis PloS One. 7(12), e52649 RENAULT, A.D., KUNWAR, P.S. and LEHMANN, R., 2010. Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in Drosophila Development. 137(11), 1815-1823 RENAULT, A. D., RICARDO, S., KUNWAR, P. S., SANTOS, A., STARZ-GAIANO, M., STEIN, J. A. and LEHMANN, R., 2009. Hedgehog does not guide migrating Drosophila germ cells Developmental Biology. 328(2), 355-62 KUNWAR, P.S., SANO, H., RENAULT, A.D., BARBOSA, V., FUSE, N. and LEHMANN, R., 2008. Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin Journal of Cell Biology. 183(1), 157-168 RENAULT, A. D. and LEHMANN, R., 2006. Follow the fatty brick road: lipid signaling in cell migration Current opinion in genetics & development. 16(4), 348-54 SANO, H., RENAULT, A. D. and LEHMANN, R., 2005. Control of lateral migration and germ cell elimination by the Drosophila melanogaster lipid phosphate phosphatases Wunen and Wunen 2 The Journal of Cell Biology. 171(4), 675-83 RENAULT, A. D., SIGAL, Y. J., MORRIS, A. J. and LEHMANN, R., 2004. Soma-germ line competition for lipid phosphate uptake regulates germ cell migration and survival Science. 305(5692), 1963-6 ZHANG, X. H., AXTON, J. M., DRINJAKOVIC, J., LORENZ, L., WHITE-COOPER, H. and RENAULT, A. D., 2004. Spatial and temporal control of mitotic cyclins by the Gnu regulator of embryonic mitosis in Drosophila: Journal of cell science 117(Pt 16), 3571-8 RENAULT, A. D. and AXTON, J. M., 2003. Identification of plu genes and cis-acting elements of PCNA in the Drosophila genus using conservation of gene order: Gene 307, 77-86 RENAULT, A. D., ZHANG, X. H., ALPHEY, L. S., FRENZ, L. M., GLOVER, D. M., SAUNDERS, R. D. and AXTON, J. M., 2003. giant nuclei is essential in the cell cycle transition from meiosis to mitosis: Development 130(13), 2997-3005 RENAULT, A. D., STARZ-GAIANO, M. and LEHMANN, R., 2002. Metabolism of sphingosine 1-phosphate and lysophosphatidic acid: a genome wide analysis of gene expression in Drosophila: Mechanisms of development 119 Suppl 1, S293-301