Brock, Matthias - University of Nottingham

个人简介

1994-1995 Basic studies in Biology at the Johannes-Guternberg University Mainz, Germany; 1995-1998 Studies of Microbiology at the Philipps University Marburg, Germany, 1997 Erasums/Sokrates exchange program with the University of Oxford, UK; 1998 Diploma in Microbiology at the Philipps University Marburg, Germany; 1998-2001 PhD student at the Phillips University Marburg, Germany; 2001 Research Associate at the Phillips University Marburg, Germany; 2001-2005 Assistant Professor at the Leibniz University Hannover, Germany; 2005 Advanced Training at the Institute Pasteur, Paris, France, 2005-2006 Group leader "Biochemistry and Physiology of Filamentous Fungi" at the Department for Molecular and Applied Microbiology at the Leibniz Institute for Natural product Research and Infection Biology, Jena, Germany; 2006-2011 Independent research group leader "Microbial Biochemistry and Physiology" at the Leibniz Institute for Natural product Research and Infection Biology, Jena, Germany; 2010 Venia Legendi at the Friedrich Schiller University Jena, Germany; 2011-2012 Head of the research group "Microbial Biochemistry and Physiology" at the Leibniz Institute for Natural product Research and Infection Biology, Jena, Germany; 2012-2015 Head of the research group "Microbial Biochemistry and Physiology" at the Friedrich Schiller University Jena, Germany; since 2015 Assistant Professor at the University of Nottingham in the Fungal Biology and Genetics Group

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NARANJO-ORTíZ MA, BROCK M, BRUNKE S, HUBE B, MARCET-HOUBEN M and GABALDóN T, 2017. Widespread Inter- and Intra-Domain Horizontal Gene Transfer of d-Amino Acid Metabolism Enzymes in Eukaryotes. Frontiers in microbiology. 7, 2001 HSIEH SH, BRUNKE S and BROCK M, 2017. Encapsulation of Antifungals in Micelles Protects Candida albicans during Gall-Bladder Infection. Frontiers in microbiology. 8, 117 FUNK, JANA, SCHAARSCHMIDT, BARBARA, SLESIONA, SILVIA, HALLSTROM, TERESIA, HORN, UWE and BROCK, MATTHIAS, 2016. The glycolytic enzyme enolase represents a plasminogen-binding protein on the surface of a wide variety of medically important fungal species. International journal of medical microbiology : IJMM. 306(1), 59-68 SAVERS, AMELIE, RASID, ORHAN, PARLATO, MARIANNA, BROCK, MATTHIAS, JOUVION, GREGORY, RYFFEL, BERNHARD, CAVAILLON, JEAN-MARC, EBERL, GERARD and IBRAHIM-GRANET, OUMAIMA, 2016. Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge. PloS one. 11(4), e0153829 GEIB, ELENA, GRESSLER, MARKUS, VIEDIERNIKOVA, IULIIA, HILLMANN, FALK, JACOBSEN, ILSE D, NIETZSCHE, SANDOR, HERTWECK, CHRISTIAN and BROCK, MATTHIAS, 2016. A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress. Cell chemical biology. 23(5), 587-97 GRESNIGT, MARK S., REKIKI, ABDESSALEM, RASID, ORHAN, SAVERS, AMELIE, JOUVION, GREGORY, DANNAOUI, ERIC, PARLATO, MARIANNA, FITTING, CATHERINE, BROCK, MATTHIAS, CAVAILLON, JEAN-MARC, VAN DE VEERDONK, FRANK L. and IBRAHIM-GRANET, OUMAIMA, 2016. Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor SCIENTIFIC REPORTS. 6, KALLEDA N, AMICH J, ARSLAN B, POREDDY S, MATTENHEIMER K, MOKHTARI Z, EINSELE H, BROCK M, HEINZE KG and BEILHACK A, 2016. Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens. Frontiers in microbiology. 7, 1107 GRESSLER M, HORTSCHANSKY P, GEIB E and BROCK M, 2015. A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster. Frontiers in microbiology. 6, 184 GRESSLER, MARKUS, MEYER, FLORIAN, HEINE, DANIEL, HORTSCHANSKY, PETER, HERTWECK, CHRISTIAN and BROCK, MATTHIAS, 2015. Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals. eLife. 4, KALLEDA, N., AMICH, J., BEILHACK, A., HEINZE, K., BROCK, M., KALLEDA, N., AMICH, J., BEILHACK, A., HEINZE, K., BROCK, M. and KALLEDA, N., 2015. Myeloid cells act as major host defense against pulmonary Aspergillus fumigatus infections under immunocompromised conditions MYCOSES. 58, 23-24 BROCK, MATTHIAS, 2015. Bringing light into the dark site of infection CYTOMETRY PART A. 87A(9), 793-794 ZAEHLE C, GRESSLER M, SHELEST E, GEIB E, HERTWECK C and BROCK M, 2014. Terrein biosynthesis in Aspergillus terreus and its impact on phytotoxicity. Chemistry & biology. 21(6), 719-31 PAPON N, COURDAVAULT V, LANOUE A, CLASTRE M and BROCK M, 2014. Illuminating fungal infections with bioluminescence. PLoS pathogens. 10(7), e1004179 JACOBSEN ID, LüTTICH A, KURZAI O, HUBE B and BROCK M, 2014. In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy. The Journal of antimicrobial chemotherapy. 69(10), 2785-96 BRUNKE S, SEIDER K, RICHTER ME, BREMER-STRECK S, RAMACHANDRA S, KIEHNTOPF M, BROCK M and HUBE B, 2014. Histidine degradation via an aminotransferase increases the nutritional flexibility of Candida glabrata. Eukaryotic cell. 13(6), 758-65 RAMACHANDRA S, LINDE J, BROCK M, GUTHKE R, HUBE B and BRUNKE S, 2014. Regulatory networks controlling nitrogen sensing and uptake in Candida albicans. PloS one. 9(3), e92734 OTZEN C, BARDL B, JACOBSEN ID, NETT M and BROCK M, 2014. Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA. The Journal of biological chemistry. 289(12), 8151-69 GALIGER C, BROCK M, JOUVION G, SAVERS A, PARLATO M and IBRAHIM-GRANET O, 2013. Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging. Antimicrobial agents and chemotherapy. 57(7), 3046-59 OTZEN C, MüLLER S, JACOBSEN ID and BROCK M, 2013. Phylogenetic and phenotypic characterisation of the 3-ketoacyl-CoA thiolase gene family from the opportunistic human pathogenic fungus Candida albicans. FEMS yeast research. 13(6), 553-64 SLESIONA S, IBRAHIM-GRANET O, OLIAS P, BROCK M and JACOBSEN ID, 2012. Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration. The Journal of infectious diseases. 205(8), 1268-77 SLESIONA S, GRESSLER M, MIHLAN M, ZAEHLE C, SCHALLER M, BARZ D, HUBE B, JACOBSEN ID and BROCK M, 2012. Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages. PloS one. 7(2), e31223 BROCK M, 2012. Application of bioluminescence imaging for in vivo monitoring of fungal infections. International journal of microbiology. 2012, 956794 CITIULO F, JACOBSEN ID, MIRAMóN P, SCHILD L, BRUNKE S, ZIPFEL P, BROCK M, HUBE B and WILSON D, 2012. Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS pathogens. 8(6), e1002777 GRESSLER M, ZAEHLE C, SCHERLACH K, HERTWECK C and BROCK M, 2011. Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus. Chemistry & biology. 18(2), 198-209 OLIAS P, GRUBER AD, HAFEZ HM, LIERZ M, SLESIONA S, BROCK M and JACOBSEN ID, 2011. Molecular epidemiology and virulence assessment of Aspergillus fumigatus isolates from white stork chicks and their environment. Veterinary microbiology. 148(2-4), 348-55