Diggle, Steve - University of Nottingham

个人简介

I graduated in Biological Sciences (B.Sc, University of Salford, 1997, 1st Class) prior to undertaking a Ph.D in molecular microbiology studying quorum sensing in Pseudomonas aeruginosa (University of Nottingham, 2001). I worked as a Postdoctoral Fellow on both EU and BBSRC funded grants, before obtaining a Royal Society University Fellowship (2006-2014). I was promoted to Associate Professor in 2013. I currently serve on the editorial boards of Microbiology and Microbiology Open. I have previously served on the editorial boards of FEMS Microbiology Letters, BMC Microbiology and Royal Society Open Science. I was an elected member of the Microbiology Society Council (2012-2016) and served on their conference and policy committees. In my spare time I play bass guitar. I have played in a number of covers band and recorded some original music in a band called Meaner.

近期论文

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RUPARELL A, DUBERN JF, ORTORI CA, HARRISON F, HALLIDAY NM, EMTAGE A, ASHAWESH MM, LAUGHTON CA, DIGGLE SP, WILLIAMS P, BARRETT DA and HARDIE KR, 2016. The fitness burden imposed by synthesising quorum sensing signals. Scientific reports. 6, 33101 MELAUGH G, HUTCHISON J, KRAGH KN, IRIE Y, ROBERTS A, BJARNSHOLT T, DIGGLE SP, GORDON VD and ALLEN RJ, 2016. Shaping the Growth Behaviour of Biofilms Initiated from Bacterial Aggregates. PloS one. 11(3), e0149683 KRAGH KN, HUTCHISON JB, MELAUGH G, RODESNEY C, ROBERTS AE, IRIE Y, JENSEN P?, DIGGLE SP, ALLEN RJ, GORDON V and BJARNSHOLT T, 2016. Role of Multicellular Aggregates in Biofilm Formation. mBio. 7(2), e00237 HARRISON F and DIGGLE SP, 2016. An ex vivo lung model to study bronchioles infected with Pseudomonas aeruginosa biofilms. Microbiology (Reading, England). 162(10), 1755-1760 DARCH SE, MCNALLY A, HARRISON F, CORANDER J, BARR HL, PASZKIEWICZ K, HOLDEN S, FOGARTY A, CRUSZ SA and DIGGLE SP, 2015. Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection. Scientific reports. 5, 7649 POPAT R, POLLITT EJG, HARRISON F, NAGHRA H, HONG K, CHAN K, GRIFFIN AS, WILLIAMS P, BROWN SP, WEST SA and DIGGLE SP, 2015. Conflict of interest and signal interference lead to the breakdown of honest signalling. Evolution; international journal of organic evolution. (In Press.) HARRISON F, ROBERTS AEL, GABRILSKA R, RUMBAUGH KP, LEE C and DIGGLE SP, 2015. A 1,000-Year-Old Antimicrobial Remedy with Antistaphylococcal Activity. mBio. 6(4), ROBERTS AEL, KRAGH KN, BJARNSHOLT T and DIGGLE SP, 2015. The limitations of in vitro experimentation in understanding biofilms and chronic infection. Journal of molecular biology. (In Press.) POLLITT EJ, CRUSZ SA and DIGGLE SP, 2015. Staphylococcus aureus forms spreading dendrites that have characteristics of active motility. Scientific reports. 5, 17698 POLLITT EJG, WEST SA, CRUSZ SA, BURTON-CHELLEW MN and DIGGLE SP, 2014. Cooperation, quorum sensing and evolution of virulence in Staphylococcus aureus. Infection and immunity. 82, 1045-1051 JIRICNY N, MOLIN S, FOSTER K, DIGGLE SP, SCANLAN PD, GHOUL M, JOHANSEN HK, SANTORELLI LA, POPAT R, WEST SA and GRIFFIN AS, 2014. Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis. PloS one. 9(1), e83124 GHOUL M, WEST SA, DIGGLE SP and GRIFFIN AS, 2014. An experimental test of whether cheating is context dependent. Journal of evolutionary biology. (In Press.) CORNFORTH DM, POPAT R, MCNALLY L, GURNEY J, SCOTT-PHILLIPS TC, IVENS A, DIGGLE SP and BROWN SP, 2014. Combinatorial quorum sensing allows bacteria to resolve their social and physical environment. Proceedings of the National Academy of Sciences of the United States of America. 111, 4280-4284 ALLEN RC, POPAT R, DIGGLE SP and BROWN SP, 2014. Targeting virulence: can we make evolution-proof drugs? Nature reviews. Microbiology. 12(4), 300-8 SCOTT-PHILLIPS TC, GURNEY J, IVENS A, DIGGLE SP and POPAT R, 2014. Combinatorial communication in bacteria: implications for the origins of linguistic generativity. PloS one. 9(4), e95929 LAABEI M, JAMIESON WD, LEWIS SE, DIGGLE SP and JENKINS ATA, 2014. A new assay for rhamnolipid detection-important virulence factors of Pseudomonas aeruginosa. Applied microbiology and biotechnology. (In Press.) HARRISON, FREYA, MURULI, ANEESHA, HIGGINS, STEVEN and DIGGLE, STEPHEN P., 2014. Development of an Ex Vivo Porcine Lung Model for Studying Growth, Virulence, and Signaling of Pseudomonas aeruginosa INFECTION AND IMMUNITY. 82(8), 3312-3323 FRIMAN, VILLE-PETRI, DIGGLE, STEPHEN P. and BUCKLING, ANGUS, 2013. Protist predation can favour cooperation within bacterial species BIOLOGY LETTERS. 9(5), SCHUSTER, MARTIN, SEXTON, D. JOSEPH, DIGGLE, STEPHEN P. and GREENBERG, E. PETER, 2013. Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application ANNUAL REVIEW OF MICROBIOLOGY, VOL 67. 67, 43-63 CRUSZ, SHANIKA A., POPAT, ROMAN, RYBTKE, MORTEN THEIL, CAMARA, MIGUEL, GIVSKOV, MICHAEL, TOLKER-NIELSEN, TIM, DIGGLE, STEPHEN P. and WILLIAMS, PAUL, 2012. Bursting the bubble on bacterial biofilms: a flow cell methodology BIOFOULING. 28(8), 835-842 GOLDSTONE, ROBERT J., POPAT, ROMAN, FLETCHER, MATTHEW P., CRUSZ, SHANIKA A. and DIGGLE, STEPHEN P., 2012. Quorum Sensing and Social Interactions in Microbial Biofilms MICROBIAL BIOFILM: CURRENT RESEARCH AND APPLICATIONS. 1-24 RUMBAUGH, KENDRA P., TRIVEDI, URVISH, WATTERS, CHASE, BURTON-CHELLEW, MAXWELL N., DIGGLE, STEPHEN P. and WEST, STUART A., 2012. Kin selection, quorum sensing and virulence in pathogenic bacteria PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 279(1742), 3584-3588 WEST, STUART A., WINZER, KLAUS, GARDNER, ANDY and DIGGLE, STEPHEN P., 2012. Quorum sensing and the confusion about diffusion TRENDS IN MICROBIOLOGY. 20(12), 586-594 POPAT, ROMAN, CRUSZ, SHANIKA A., MESSINA, MARCO, WILLIAMS, PAUL, WEST, STUART A. and DIGGLE, STEPHEN P., 2012. Quorum-sensing and cheating in bacterial biofilms PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 279(1748), 4765-4771 YOULE, MERRY, ROHWER, FOREST, STACY, APOLLO, WHITELEY, MARVIN, STEEL, BRADLEY C., DELALEZ, NICOLAS J., NORD, ASHLEY L., BERRY, RICHARD M., ARMITAGE, JUDITH P., KAMOUN, SOPHIEN, HOGENHOUT, SASKIA, DIGGLE, STEPHEN P., GURNEY, JAMES, POLLITT, ERIC J. G., BOETIUS, ANTJE and CARY, S. CRAIG, 2012. The Microbial Olympics (vol 10, pg 583, 2012) NATURE REVIEWS MICROBIOLOGY. 10(9), 654-654