近期论文

查看导师最新文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

RICHENS JL, SPENCER HL, BUTLER M, CANTLAY F, VERE KA, BAJAJ N, MORGAN K and O'SHEA P, 2016. Rationalising the role of Keratin 9 as a biomarker for Alzheimer's disease. Scientific reports. 6, 22962 BARBER IS, GARCíA-CáRDENAS JM, SAKDAPANICHKUL C, DEACON C, ZAPATA ERAZO G, GUERREIRO R, BRAS J, HERNANDEZ D, SINGLETON A, GUETTA-BARANES T, BRAAE A, CLEMENT N, PATEL T, BROOKES K, MEDWAY C, CHAPPELL S, MANN DM, and MORGAN K, 2016. Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease. Neurobiology of aging. 39, 220.e1-7 SASSI C, RIDGE PG, NALLS MA, GIBBS R, DING J, LUPTON MK, TROAKES C, LUNNON K, AL-SARRAJ S, BROWN KS, MEDWAY C, LORD J, TURTON J, , MORGAN K, POWELL JF, KAUWE JS, CRUCHAGA C, BRAS J, GOATE AM, SINGLETON AB, GUERREIRO R and HARDY J, 2016. Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease. PloS one. 11(6), e0150079 2016. ABCA7 p.G215S as potential protective factor for Alzheimer's disease. Neurobiology of aging. (In Press.) ESCOTT-PRICE V, SIMS R, BANNISTER C, HAROLD D, VRONSKAYA M, MAJOUNIE E, BADARINARAYAN N, , , MORGAN K, PASSMORE P, HOLMES C, POWELL J, BRAYNE C, GILL M, MEAD S, GOATE A, CRUCHAGA C, LAMBERT JC, VAN DUIJN C, MAIER W, RAMIREZ A, HOLMANS P, JONES L, HARDY J, SESHADRI S, SCHELLENBERG GD, AMOUYEL P and WILLIAMS J, 2015. Common polygenic variation enhances risk prediction for Alzheimer's disease. Brain : a journal of neurology. 138(Pt 12), 3673-84 JONES, LESLEY, LAMBERT, JEAN-CHARLES, WANG, LI-SAN, CHOI, SEUNG-HOAN, HAROLD, DENISE, VEDERNIKOV, ALEXEY, ESCOTT-PRICE, VALENTINA, STONE, TIMOTHY, RICHARDS, ALEXANDER, BELLENGUEZ, CELINE, IBRAHIM-VERBAAS, CARLA A., NAJ, ADAM C., SIMS, REBECCA, GERRISH, AMY, JUN, GYUNGAH, DESTEFANO, ANITA L., BIS, JOSHUA C., BEECHAM, GARY W., GRENIER-BOLEY, BENJAMIN, RUSSO, GIANCARLO, THORNTON-WELLS, TRICIA A., JONES, NICOLA, SMITH, ALBERT V., CHOURAKI, VINCENT, THOMAS, CHARLENE, IKRAM, M. ARFAN, ZELENIKA, DIANA, VARDARAJAN, BADRI N., KAMATANI, YOICHIRO, LIN, CHIAO-FENG, SCHMIDT, HELENA, KUNKLE, BRIAN W., DUNSTAN, MELANIE L., RUIZ, AGUSTIN, BIHOREAU, MARIE-THERESE, REITZ, CHRISTIANE, PASQUIER, FLORENCE, HOLLINGWORTH, PAUL, HANON, OLIVIER, FITZPATRICK, ANNETTE L., BUXBAUM, JOSEPH D., CAMPION, DOMINIQUE, CRANE, PAUL K., BECKER, TIM, GUDNASON, VILMUNDUR, CRUCHAGA, CARLOS, CRAIG, DAVID, AMIN, NAJAF, BERR, CLAUDINE, LOPEZ, OSCAR L., DE JAGER, PHILIP L., DERAMECOURT, VINCENT, JOHNSTON, JANET A., EVANS, DENIS, LOVESTONE, SIMON, LETTENEUR, LUC, KORNHUBER, JOHANES, TARRAGA, LLUIS, RUBINSZTEIN, DAVID C., EIRIKSDOTTIR, GUDNY, SLEEGERS, KRISTEL, GOATE, ALISON M., FIEVET, NATHALIE, HUENTELMAN, MATTHEW J., GILL, MICHAEL, EMILSSON, VALUR, BROWN, KRISTELLE, KAMBOH, M. ILYAS, KELLER, LINA, BARBERGER-GATEAU, PASCALE, MCGUINNESS, BERNADETTE, LARSON, ERIC B., MYERS, AMANDA J., DUFOUIL, CAROLE, TODD, STEPHEN, WALLON, DAVID, LOVE, SETH, KEHOE, PAT, ROGAEVA, EKATERINA, GALLACHER, JOHN, ST GEORGE-HYSLOP, PETER, CLARIMON, JORDI, LLEO, ALBERTI, BAYER, ANTHONY, TSUANG, DEBBY W., YU, LEI, TSOLAKI, MAGDA, BOSSU, PAOLA, SPALLETTA, GIANFRANCO, PROITSI, PETRA, COLLINGE, JOHN, SORBI, SANDRO, GARCIA, FIORENTINO SANCHEZ, FOX, NICK, HARDY, JOHN, DENIZ NARANJO, MARIA CANDIDA, RAZQUIN, CRISTINA, BOSCO, PAOLA, CLARKE, ROBERT, BRAYNE, CAROL, GALIMBERTI, DANIELA, MANCUSO, MICHELANGELO, MOEBUS, SUSANNE, MECOCCI, PATRIZIA, DEL ZOMPO, MARIA, MAIER, WOLFGANG, HAMPEL, HARALD, PILOTTO, ALBERTO, BULLIDO, MARIA, PANZA, FRANCESCO, CAFFARRA, PAOLO, NACMIAS, BENEDETTA, GILBERT, JOHN R., MAYHAUS, MANUEL, JESSEN, FRANK, DICHGANS, MARTIN, LANNFELT, LARS, HAKONARSON, HAKON, PICHLER, SABRINA, CARRASQUILLO, MINERVA M., INGELSSON, MARTIN, BEEKLY, DUANE, ALAVAREZ, VICTORIA, ZOU, FANGGENG, VALLADARES, OTTO, YOUNKIN, STEVEN G., COTO, ELIECER, HAMILTON-NELSON, KARA L., MATEO, IGNACIO, OWEN, MICHAEL J., FABER, KELLEY M., JONSSON, PALMI V., COMBARROS, ONOFRE, O'DONOVAN, MICHAEL C., CANTWELL, LAURA B., SOININEN, HILKKA, BLACKER, DEBORAH, MEAD, SIMON, MOSLEY, THOMAS H., JR., BENNETT, DAVID A., HARRIS, TAMARA B., FRATIGLIONI, LAURA, HOLMES, CLIVE, DE BRUIJN, RENEE F. A. G., PASSMORE, PETER, MONTINE, THOMAS J., BETTENS, KAROLIEN, ROTTER, JEROME I., BRICE, ALEXIS, MORGAN, KEVIN, FOROUD, TATIANA M., KUKULL, WALTER A., HANNEQUIN, DIDIER, POWELL, JOHN F., NAILS, MICHAEL A., RITCHIE, KAREN, LUNETTA, KATHRYN L., KAUWE, JOHN S. K., BOERWINKLE, ERIC, RIEMENSCHNEIDER, MATTHIAS, BOADA, MERCE, HILTUNEN, MIKKO, MARTIN, EDEN R., PASTOR, PAU, SCHMIDT, REINHOLD, RUJESCU, DAN, DARTIGUES, JEAN-FRANCOIS, MAYEUX, RICHARD, TZOURIO, CHRISTOPHE, HOFMAN, ALBERT, NOETHEN, MARKUS M., GRAFF, CAROLINE, PSATY, BRUCE M., HAINES, JONATHAN L., LATHROP, MARK, PERICAK-VANCE, MARGARET A., LAUNER, LENORE J., FARRER, LINDSAY A., VAN DUIJN, CORNELIA M., VAN BROECKHOVEN, CHRISTINE, RAMIREZ, ALFREDO, SCHELLENBERG, GERARD D., SESHADRI, SUDHA, AMOUYEL, PHILIPPE, WILLIAMS, JULIE and HOLMANS, PETER A., 2015. Convergent genetic and expression data implicate immunity in Alzheimer's disease ALZHEIMERS & DEMENTIA. 11(6), 658-671 BRAAE A, MEDWAY C, CARRASQUILLO M, YOUNKIN S, , KEHOE PG and MORGAN K, 2015. Blood type gene locus has no influence on ACE association with Alzheimer's disease. Neurobiology of aging. 36(4), 1767.e1-2 SEVLEVER D, ZOU F, MA L, CARRASQUILLO S, CRUMP MG, CULLEY OJ, HUNTER TA, BISCEGLIO GD, YOUNKIN L, ALLEN M, CARRASQUILLO MM, SANDO SB, AASLY JO, DICKSON DW, GRAFF-RADFORD NR, PETERSEN RC, DEáK F, and BELBIN O, 2015. Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility. Molecular neurodegeneration. 10, 18 SEVLEVER D, ZOU F, MA L, CARRASQUILLO S, CRUMP MG, CULLEY OJ, HUNTER TA, BISCEGLIO GD, YOUNKIN L, ALLEN M, CARRASQUILLO MM, SANDO SB, AASLY JO, DICKSON DW, GRAFF-RADFORD NR, PETERSEN RC, DEáK F, and BELBIN O, 2015. Erratum to: Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility. Molecular neurodegeneration. 10, 49 CARRASQUILLO MM, BARBER I, LINCOLN SJ, MURRAY ME, CAMSARI GB, KHAN QU, NGUYEN T, MA L, BISCEGLIO GD, CROOK JE, YOUNKIN SG, DICKSON DW, BOEVE BF, GRAFF-RADFORD NR, MORGAN K and ERTEKIN-TANER N, 2015. Evaluating pathogenic dementia variants in posterior cortical atrophy. Neurobiology of aging. 37, 38-44 GUERREIRO R, ESCOTT-PRICE V, DARWENT L, PARKKINEN L, ANSORGE O, HERNANDEZ DG, NALLS MA, CLARK L, HONIG L, MARDER K, VAN DER FLIER W, HOLSTEGE H, LOUWERSHEIMER E, LEMSTRA A, SCHELTENS P, ROGAEVA E, ST GEORGE-HYSLOP P, LONDOS E, ZETTERBERG H, ORTEGA-CUBERO S, PASTOR P, FERMAN TJ, GRAFF-RADFORD NR, ROSS OA, BARBER I, BRAAE A, BROWN K, MORGAN K, MAETZLER W, BERG D, TROAKES C, AL-SARRAJ S, LASHLEY T, COMPTA Y, REVESZ T, LEES A, CAIRNS NJ, HALLIDAY GM, MANN D, PICKERING-BROWN S, POWELL J, LUNNON K, LUPTON MK, , DICKSON D, HARDY J, SINGLETON A and BRAS J, 2015. Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiology of aging. 38, 214.e7-10 JOANNA L RICHENS, KELLY-ANN VERE, ROGER A LIGHT, DANIELE SORIA, JONATHAN GARIBALDI, A DAVID SMITH, DONALD WARDEN, GORDON WILCOCK, NIN BAJAJ, KEVIN MORGAN and PAUL O'SHEA, 2014. Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluid International Journal of Molecular Epidemiology and Genetics. 5(2), 53-70 CRUCHAGA C, KARCH CM, JIN SC, BENITEZ BA, CAI Y, GUERREIRO R, HARARI O, NORTON J, BUDDE J, BERTELSEN S, JENG AT, COOPER B, SKORUPA T, CARRELL D, LEVITCH D, HSU S, CHOI J, RYTEN M, UK BRAIN EXPRESSION CONSORTIUM, HARDY J, RYTEN M, TRABZUNI D, WEALE ME, RAMASAMY A, SMITH C, SASSI C, BRAS J, GIBBS JR, HERNANDEZ DG, LUPTON MK, POWELL J, FORABOSCO P, RIDGE PG, CORCORAN CD, TSCHANZ JT, NORTON MC, MUNGER RG, SCHMUTZ C, LEARY M, DEMIRCI FY, BAMNE MN, WANG X, LOPEZ OL, GANGULI M, MEDWAY C, TURTON J, LORD J, BRAAE A, BARBER I, BROWN K, ALZHEIMER’S RESEARCH UK CONSORTIUM, PASSMORE P, CRAIG D, JOHNSTON J, MCGUINNESS B, TODD S, HEUN R, K?LSCH H, KEHOE PG, HOOPER NM, VARDY ERLC, MANN DM, PICKERING-BROWN S, BROWN K, KALSHEKER N, LOWE J, MORGAN K, DAVID SMITH A, WILCOCK G, WARDEN D, HOLMES C, PASTOR P, LORENZO-BETANCOR O, BRKANAC Z, SCOTT E, TOPOL E, MORGAN K, ROGAEVA E, SINGLETON AB, HARDY J, KAMBOH MI, ST GEORGE-HYSLOP P, CAIRNS N, MORRIS JC, KAUWE JSK and GOATE AM, 2014. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature. 505(7484), 550-4 SASSI C, GUERREIRO R, GIBBS R, DING J, LUPTON MK, TROAKES C, AL-SARRAJ S, NIBLOCK M, GALLO J, ADNAN J, KILLICK R, BROWN KS, MEDWAY C, LORD J, TURTON J, BRAS J, ALZHEIMER'S RESEARCH UK CONSORTIUM, MORGAN K, POWELL JF, SINGLETON A and HARDY J, 2014. Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease. Neurobiology of aging. 35(12), 2881.e1-6 BRAS J, GUERREIRO R, DARWENT L, PARKKINEN L, ANSORGE O, ESCOTT-PRICE V, HERNANDEZ DG, NALLS MA, CLARK LN, HONIG LS, MARDER K, VAN DER FLIER WM, LEMSTRA A, SCHELTENS P, ROGAEVA E, ST GEORGE-HYSLOP P, LONDOS E, ZETTERBERG H, ORTEGA-CUBERO S, PASTOR P, FERMAN TJ, GRAFF-RADFORD NR, ROSS OA, BARBER I, BRAAE A, BROWN K, MORGAN K, MAETZLER W, BERG D, TROAKES C, AL-SARRAJ S, LASHLEY T, COMPTA Y, REVESZ T, LEES A, CAIRNS N, HALLIDAY GM, MANN D, PICKERING-BROWN S, DICKSON DW, SINGLETON A and HARDY J, 2014. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Human molecular genetics. 23(23), 6139-46 ESCOTT-PRICE V, BELLENGUEZ C, WANG L, CHOI S, HAROLD D, JONES L, HOLMANS P, GERRISH A, VEDERNIKOV A, RICHARDS A, DESTEFANO AL, LAMBERT J, IBRAHIM-VERBAAS CA, NAJ AC, SIMS R, JUN G, BIS JC, BEECHAM GW, GRENIER-BOLEY B, RUSSO G, THORNTON-WELLS TA, DENNING N, SMITH AV, CHOURAKI V, THOMAS C, IKRAM MA, ZELENIKA D, VARDARAJAN BN, KAMATANI Y, LIN C, SCHMIDT H, KUNKLE B, DUNSTAN ML, VRONSKAYA M, UNITED KINGDOM BRAIN EXPRESSION CONSORTIUM, JOHNSON AD, RUIZ A, BIHOREAU M, REITZ C, PASQUIER F, HOLLINGWORTH P, HANON O, FITZPATRICK AL, BUXBAUM JD, CAMPION D, CRANE PK, BALDWIN C, BECKER T, GUDNASON V, CRUCHAGA C, CRAIG D, AMIN N, BERR C, LOPEZ OL, DE JAGER PL, DERAMECOURT V, JOHNSTON JA, EVANS D, LOVESTONE S, LETENNEUR L, HERNáNDEZ I, RUBINSZTEIN DC, EIRIKSDOTTIR G, SLEEGERS K, GOATE AM, FIéVET N, HUENTELMAN MJ, GILL M, BROWN K, KAMBOH MI, KELLER L, BARBERGER-GATEAU P, MCGUINNESS B, LARSON EB, MYERS AJ, DUFOUIL C, TODD S, WALLON D, LOVE S, ROGAEVA E, GALLACHER J, GEORGE-HYSLOP PS, CLARIMON J, LLEO A, BAYER A, TSUANG DW, YU L, TSOLAKI M, BOSSù P, SPALLETTA G, PROITSI P, COLLINGE J, SORBI S, GARCIA FS, FOX NC, HARDY J, NARANJO MCD, BOSCO P, CLARKE R, BRAYNE C, GALIMBERTI D, SCARPINI E, BONUCCELLI U, MANCUSO M, SICILIANO G, MOEBUS S, MECOCCI P, ZOMPO MD, MAIER W, HAMPEL H, PILOTTO A, FRANK-GARCíA A, PANZA F, SOLFRIZZI V, CAFFARRA P, NACMIAS B, PERRY W, MAYHAUS M, LANNFELT L, HAKONARSON H, PICHLER S, CARRASQUILLO MM, INGELSSON M, BEEKLY D, ALVAREZ V, ZOU F, VALLADARES O, YOUNKIN SG, COTO E, HAMILTON-NELSON KL, GU W, RAZQUIN C, PASTOR P, MATEO I, OWEN MJ, FABER KM, JONSSON PV, COMBARROS O, O'DONOVAN MC, CANTWELL LB, SOININEN H, BLACKER D, MEAD S, MOSLEY TH, BENNETT DA, HARRIS TB, FRATIGLIONI L, HOLMES C, DE BRUIJN RFAG, PASSMORE P, MONTINE TJ, BETTENS K, ROTTER JI, BRICE A, MORGAN K, FOROUD TM, KUKULL WA, HANNEQUIN D, POWELL JF, NALLS MA, RITCHIE K, LUNETTA KL, KAUWE JSK, BOERWINKLE E, RIEMENSCHNEIDER M, BOADA M, HILTUNEN M, MARTIN ER, SCHMIDT R, RUJESCU D, DARTIGUES J, MAYEUX R, TZOURIO C, HOFMAN A, N?THEN MM, GRAFF C, PSATY BM, HAINES JL, LATHROP M, PERICAK-VANCE MA, LAUNER LJ, VAN BROECKHOVEN C, FARRER LA, VAN DUIJN CM, RAMIREZ A, SESHADRI S, SCHELLENBERG GD, AMOUYEL P, WILLIAMS J and CARDIOVASCULAR HEALTH STUDY (CHS), 2014. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PloS one. 9(6), e94661 SASSI C, GUERREIRO R, GIBBS R, DING J, LUPTON MK, TROAKES C, LUNNON K, AL-SARRAJ S, BROWN KS, MEDWAY C, LORD J, TURTON J, MANN D, SNOWDEN J, NEARY D, HARRIS J, BRAS J, ARUK CONSORTIUM, MORGAN K, POWELL JF, SINGLETON A and HARDY J, 2014. Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease. Neurobiology of aging. 35(10), 2422.e13-6 RICHENS JL, MORGAN K and O'SHEA P, 2014. Reverse engineering of Alzheimer's disease based on biomarker pathways analysis. Neurobiology of aging. 35(9), 2029-38 MEDWAY CW, ABDUL-HAY S, MIMS T, MA L, BISCEGLIO G, ZOU F, PANKRATZ S, SANDO SB, AASLY JO, BARCIKOWSKA M, SIUDA J, WSZOLEK ZK, ROSS OA, CARRASQUILLO M, DICKSON DW, GRAFF-RADFORD N, PETERSEN RC, ERTEKIN-TANER N, MORGAN K, BU G and YOUNKIN SG, 2014. ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease. Molecular neurodegeneration. 9, 11 MEDWAY C and MORGAN K, 2014. Review: The genetics of Alzheimer's disease; putting flesh on the bones. Neuropathology and applied neurobiology. 40(2), 97-105 BENITEZ BA, JIN SC, GUERREIRO R, GRAHAM R, LORD J, HAROLD D, SIMS R, LAMBERT J, GIBBS JR, BRAS J, SASSI C, HARARI O, BERTELSEN S, LUPTON MK, POWELL J, BELLENGUEZ C, BROWN K, MEDWAY C, HADDICK PCG, VAN DER BRUG MP, BHANGALE T, ORTMANN W, BEHRENS T, MAYEUX R, PERICAK-VANCE MA, FARRER LA, SCHELLENBERG GD, HAINES JL, TURTON J, BRAAE A, BARBER I, FAGAN AM, HOLTZMAN DM, MORRIS JC, 3C STUDY GROUP, EADI CONSORTIUM, ALZHEIMER'S DISEASE GENETIC CONSORTIUM (ADGC), ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE (ADNI), GERAD CONSORTIUM, WILLIAMS J, KAUWE JSK, AMOUYEL P, MORGAN K, SINGLETON A, HARDY J, GOATE AM and CRUCHAGA C, 2014. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiology of aging. 35(6), 1510.e19-26 MEDWAY C, COMBARROS O, CORTINA-BORJA M, BUTLER HT, IBRAHIM-VERBAAS CA, DE BRUIJN RFAG, KOUDSTAAL PJ, VAN DUIJN CM, IKRAM MA, MATEO I, SáNCHEZ-JUAN P, LEHMANN MG, HEUN R, K?LSCH H, DELOUKAS P, HAMMOND N, COTO E, ALVAREZ V, KEHOE PG, BARBER R, WILCOCK GK, BROWN K, BELBIN O, WARDEN DR, SMITH AD, MORGAN K and LEHMANN DJ, 2014. The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project. European journal of human genetics : EJHG. 22(2), 216-20 BULLOCK JM, MEDWAY C, CORTINA-BORJA M, TURTON JC, PRINCE JA, IBRAHIM-VERBAAS CA, SCHUUR M, BRETELER MM, VAN DUIJN CM, KEHOE PG, BARBER R, COTO E, ALVAREZ V, DELOUKAS P, HAMMOND N, COMBARROS O, MATEO I, WARDEN DR, LEHMANN MG, BELBIN O, BROWN K, WILCOCK GK, HEUN R, K?LSCH H, SMITH AD, LEHMANN DJ and MORGAN K, 2013. Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiology of aging. 34(4), 1309.e1-7