Greenhaff, Paul - University of Nottingham

个人简介

Paul Greenhaff is Professor of Muscle Metabolism at the University of Nottingham. He heads the Metabolic and Molecular Physiology Research Group at Nottingham, is Deputy Director of the MRC/ARUK Centre for Musculoskeletal Ageing Research and is a member of the ARUK Centre for Sport, Exercise and Osteoarthritis. Paul is also a member of BBSRC Research Panel A, a member of the Editorial Boards of Acta Physiologica and the Scandinavian Journal of Medicine and Science in Sports. In 2001 he delivered the John French Lecture to the British Atherosclerosis Society and was awarded the Scientific Achievement Award by the Society for Guanidino Compounds in Biology and Medicine.

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SHANNON, CHRIS E., NIXON, ALINE V., GREENHAFF, PAUL L. and STEPHENS, FRANCIS B., 2016. Protein ingestion acutely inhibits insulin-stimulated muscle carnitine uptake in healthy young men AMERICAN JOURNAL OF CLINICAL NUTRITION. 103(1), 276-282 CHEE C, SHANNON CE, BURNS A, SELBY AL, WILKINSON D, SMITH K, GREENHAFF PL and STEPHENS FB, 2016. Relative Contribution of Intramyocellular Lipid to Whole-Body Fat Oxidation Is Reduced With Age but Subsarcolemmal Lipid Accumulation and Insulin Resistance Are Only Associated With Overweight Individuals. Diabetes. 65(4), 840-50 PHILIP J. ATHERTON, PAUL L. GREENHAFF, STUART M. PHILLIPS, SUE C. BODINE, CHRISTOPHER M. ADAMS and CHARLES H. LANG, 2016. Control of Skeletal Muscle Atrophy in Response to Disuse: Clinical/Preclinical Contentions and Fallacies of Evidence. American journal of physiology. Endocrinology and metabolism. ajpendo.00257.2016 PAUL A. ROBERTS, JOHN FOX, NICHOLAS PEIRCE, SIMON W. JONES, ANNA CASEY and PAUL L. GREENHAFF, 2016. Creatine ingestion augments dietary carbohydrate mediated muscle glycogen supercompensation during the initial 24 h of recovery following prolonged exhaustive exercise in humans. Amino acids. 48(8), 1831–1842 BROOK MS, WILKINSON DJ, MITCHELL MK, LUND JN, PHILLIPS BE, SZEWCYZK NJ, GREENHAFF PL, SMITH K and ATHERTON PJ, 2016. Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans. The Journal of physiology. (In Press.) RUDRAPPA SS, WILKINSON DJ, GREENHAFF PL, SMITH K, IDRIS I and ATHERTON PJ, 2016. Human Skeletal Muscle Disuse Atrophy: Effects on Muscle Protein Synthesis, Breakdown, and Insulin Resistance-A Qualitative Review. Frontiers in physiology. 7, 361 GAFFNEY CJ, SHEPHARD F, CHU J, BAILLIE DL, ROSE A, CONSTANTIN-TEODOSIU D, GREENHAFF PL and SZEWCZYK NJ, 2016. Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C.?elegans muscle. Journal of cachexia, sarcopenia and muscle. 7(2), 181-92 MALLINSON JE, MARIMUTHU K, MURTON A, SELBY A, SMITH K, CONSTANTIN-TEODOSIU D, RENNIE MJ and GREENHAFF PL, 2015. Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression. The Journal of physiology. 593(5), 1239-1257 BROOK MS, WILKINSON DJ, MITCHELL WK, LUND JN, SZEWCZYK NJ, GREENHAFF PL, SMITH K and ATHERTON PJ, 2015. Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(11), 4485-96 ETHERIDGE, TIMOTHY, RAHMAN, MIZANUR, GAFFNEY, CHRISTOPHER J., SHAW, DEBRA, SHEPHARD, FREYA, MAGUDIA, JIGNESH, SOLOMON, DEEPAK E., MILNE, THOMAS, BLAWZDZIEWICZ, JERZY, CONSTANTIN-TEODOSIU, DUMITRU, GREENHAFF, PAUL L., VANAPALLI, SIVA A. and SZEWCZYK, NATHANIEL J., 2015. The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans FASEB JOURNAL. 29(4), 1235-1246 MURTON, ANDREW J., MARIMUTHU, KANAGARAJ, MALLINSON, JOANNE E., SELBY, ANNA L., SMITH, KENNETH, RENNIE, MICHAEL J. and GREENHAFF, PAUL L., 2015. Obesity Appears to Be Associated With Altered Muscle Protein Synthetic and Breakdown Responses to Increased Nutrient Delivery in Older Men, but Not Reduced Muscle Mass or Contractile Function DIABETES. 64(9), 3160-3171 ATHERTON, PHILIP J. and GREENHAFF, PAUL L., 2015. Age is just a number! Or is it? JOURNAL OF PHYSIOLOGY-LONDON. 593(3), 491-492 CONSTANTIN-TEODOSIU, DUMITRU, STEPHENS, FRANCIS B. and GREENHAFF, PAUL L., 2015. Perpetual muscle PDH activation in PDH kinase knockout mice protects against high-fat feeding-induced muscle insulin resistance PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 112(8), E824-E824 BUKHARI, SYED S. I., PHILLIPS, BETHAN E., WILKINSON, DANIEL J., LIMB, MARIE C., RANKIN, DEBBIE, MITCHELL, WILLIAM K., KOBAYASHI, HISAMINE, GREENHAFF, PAUL L., SMITH, KENNETH and ATHERTON, PHILIP J., 2015. Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 308(12), E1056-E1065 WILKINSON, DANIEL J., ATHERTON, PHILIP J., PHILLIPS, BETHAN E., GREENHAFF, PAUL L. and SMITH, KENNETH, 2015. Application of deuterium oxide (D2O) to metabolic research: just D2O it? Depends just how you D2O it! AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 308(9), E847-E847 BROOK, MATTHEW S., WILKINSON, DANIEL J., MITCHELL, WILLIAM K., LUND, JONATHAN N., SZEWCZYK, NATHANIEL J., GREENHAFF, PAUL L., SMITH, KEN and ATHERTON, PHILIP J., 2015. Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling FASEB JOURNAL. 29(11), 4485-4496 MALLINSON, JOANNE E., MARIMUTHU, KANAGARAJ, MURTON, ANDREW, SELBY, ANNA, SMITH, KENNETH, CONSTANTIN-TEODOSIU, DUMITRU, RENNIE, MICHAEL J. and GREENHAFF, PAUL L., 2015. Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression JOURNAL OF PHYSIOLOGY-LONDON. 593(5), 1239-1257 WILKINSON DJ, ATHERTON PJ, PHILLIPS BE, GREENHAFF PL and SMITH K, 2015. Application of deuterium oxide (D2O) to metabolic research: just D2O it? Depends just how you D2O it! American journal of physiology. Endocrinology and metabolism. 308(9), E847 BUKHARI SS, PHILLIPS BE, WILKINSON DJ, LIMB MC, RANKIN D, MITCHELL WK, KOBAYASHI H, GREENHAFF PL, SMITH K and ATHERTON PJ, 2015. Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise. American journal of physiology. Endocrinology and metabolism. 308(12), E1056-65 MURTON AJ, MARIMUTHU K, MALLINSON JE, SELBY AL, SMITH K, RENNIE MJ and GREENHAFF PL, 2015. Obesity Appears to Be Associated With Altered Muscle Protein Synthetic and Breakdown Responses to Increased Nutrient Delivery in Older Men, but Not Reduced Muscle Mass or Contractile Function. Diabetes. 64(9), 3160-71