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个人简介

I attained a BSc (HONS) degree in Applied Biochemistry from Liverpool John Moores University in 1993 following which I joined the Department of Gastroenterology at the University of Nottingham. I attained my PhD in 1999 under the supervision of Professor Yash Mahida. In 2000, I took the opportunity to join the Tissue Engineering Group within the School of Pharmacy and was rapidly promoted to Senior Research Fellow in 2002. In 2003, I was awarded a prestigious University of Nottingham sponsored Anne McLaren Research Fellowship, aimed at encouraging female scientists to pursue a career in academia. At the same time, I was appointed to a Lectureship in Tissue Engineering, a post which I took up in 2005. I was promoted to Associate Professor in 2007 and Reader in 2013. I took up the position of Head of the Tissue Engineering Group in 2015 and have recently been appointed as Head of the Division of Regenerative Medicine and Cellular Therapies.

近期论文

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AMER, MAHETAB H., ROSE, FELICITY R. A. J., WHITE, LISA J. and SHAKESHEFF, KEVIN M., 2016. A Detailed Assessment of Varying Ejection Rate on Delivery Efficiency of Mesenchymal Stem Cells Using Narrow-Bore Needles STEM CELLS TRANSLATIONAL MEDICINE. 5(3), 366-378 VAITHILINGAM, J., PRINA, E., GOODRIDGE, R. D., HAGUE, R. J. M., EDMONDSON, S., ROSE, F. R. A. J. and CHRISTIE, S. D. R., 2016. Surface chemistry of Ti6Al4V components fabricated using selective laser melting for biomedical applications: Materials Science and Engineering C Materials Science and Engineering C. 67, 294-303 BRIDGE JC, AYLOTT JW, BRIGHTLING CE, GHAEMMAGHAMI AM, KNOX AJ, LEWIS MP, ROSE FR and MORRIS GE, 2015. Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall. Journal of Visualized Experiments : JoVE. 101, e52986 KAUR D, GOMEZ E, DOE C, BERAIR R, WOODMAN L, SAUNDERS R, HOLLINS F, ROSE FR, AMRANI Y, MAY R, KEARLEY J and HUMBLES A, 2015. IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalk Allergy. 70, 556-567 HTWE, SU SU, HARRINGTON, HELEN, KNOX, ALAN, ROSE, FELICITY, AYLOTT, JONATHAN, HAYCOCK, JOHN W. and GHAEMMAGHAMI, AMIR M., 2015. Investigating NF-kappa B signaling in lung fibroblasts in 2D and 3D culture systems RESPIRATORY RESEARCH. 16, 144 GOTHARD, DAVID, SMITH, EMMA L., KANCZLER, JANOS M., BLACK, CAMERON R., WELLS, JULIA A., ROBERTS, CAROL A., WHITE, LISA J., QUTACHI, OMAR, PETO, HEATHER, RASHIDI, HASSAN, ROJO, LUIS, STEVENS, MOLLY M., EL HAJ, ALICIA J., ROSE, FELICITY R. A. J., SHAKESHEFF, KEVIN M. and OREFFO, RICHARD O. C., 2015. In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors PLOS ONE. 10(12), RAHMAN, CHERYL V., BEN-DAVID, DROR, DHILLON, AMRITPAUL, KUHN, GISELA, GOULD, TOBY W. A., MUELLER, RALPH, ROSE, FELICITY R. A. J., SHAKESHEFF, KEVIN M. and LIVNE, ERELLA, 2014. Controlled release of BMP-2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 8(1), 59-66 REINWALD, Y., JOHAL, R. K., GHAEMMAGHAMI, A. M., ROSE, F. R. A. J., HOWDLE, S. M. and SHAKESHEFF, K. M., 2014. Interconnectivity and permeability of supercritical fluid-foamed scaffolds and the effect of their structural properties on cell distribution POLYMER. 55(1), 435-444 HARRINGTON, HELEN, CATO, PAUL, SALAZAR, FABIAN, WILKINSON, MALCOLM, KNOX, ALAN, HAYCOCK, JOHN W., ROSE, FELICITY, AYLOTT, JON W. and GHAEMMAGHAMI, AMIR M., 2014. Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation MOLECULAR PHARMACEUTICS. 11(7), 2082-2091 MORRIS, G. E., BRIDGE, J. C., ELTBOLI, O. M. I., KNOX, A. J., AYLOTT, J. W., BRIGHTLING, C. E., GHAEMMAGHAMI, A. M. and ROSE, F. R. A. J., 2014. Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 307(1), L38-L47 MORRIS, G. E., BRIDGE, J. C., BRACE, L. A., KNOX, A. J., AYLOTT, J. W., BRIGHTLING, C. E., GHAEMMAGHAMI, A. M. and ROSE, F. R. A. J., 2014. A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells BIOFABRICATION. 6(3), SMITH, E. L., KANCZLER, J. M., GOTHARD, D., ROBERTS, C. A., WELLS, J. A., WHITE, L. J., QUTACHI, O., SAWKINS, M. J., PETO, H., RASHIDI, H., ROJO, L., STEVENS, M. M., EL HAJ, A. J., ROSE, F. R. A. J., SHAKESHEFF, K. M. and OREFFO, R. O. C., 2014. Evaluation of skeletal tissue repair, Part 1: Assessment of novel growth-factor-releasing hydrogels in an ex vivo chick femur defect model ACTA BIOMATERIALIA. 10(10), 4186-4196 SMITH, E. L., KANCZLER, J. M., GOTHARD, D., ROBERTS, C. A., WELLS, J. A., WHITE, L. J., QUTACHI, O., SAWKINS, M. J., PETO, H., RASHIDI, H., ROJO, L., STEVENS, M. M., EL HAJ, A. J., ROSE, F. R. A. J., SHAKESHEFF, K. M. and OREFFO, R. O. C., 2014. Evaluation of skeletal tissue repair, Part 2: Enhancement of skeletal tissue repair through dual-growth-factor-releasing hydrogels within an ex vivo chick femur defect model ACTA BIOMATERIALIA. 10(10), 4197-4205 ROGERS, CATHERINE M., DEEHAN, DAVID J., KNUTH, CALLIE A., ROSE, FELICITY R. A. J., SHAKESHEFF, KEVIN M. and OLDERSHAW, RACHEL A., 2014. Biocompatibility and enhanced osteogenic differentiation of human mesenchymal stem cells in response to surface engineered poly(D,L-lactic-co-glycolic acid) microparticles JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. 102(11), 3872-3882 ROGERS, C. M., MORRIS, G. E., GOULD, T. W., BAIL, R., TOUMPANIARI, S., HARRINGTON, H., DIXON, J. E., SHAKESHEFF, K. M., SEGAL, J. and ROSE, F. R., 2014. A novel technique for the production of electrospun scaffolds with tailored three-dimensional micro-patterns employing additive manufacturing: Biofabrication Biofabrication. 6(3), 035003 ROSE JB, PACELLI, S, EL HAJ A, DUA HS, HOPKINSON A, WHITE LJ and ROSE FRAJ, 2014. Gelatin-Based Materials in Ocular Tissue Engineering MATERIALS. 7(4), 3106-3135 HARRINGTON, H. C., ROSE, F. R. A. J., REINWALD, Y., BUTTERY, L. D. K., GHAEMMAGHAMI, A. M. and AYLOTT, J. W., 2013. Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: self-reporting scaffolds for application in tissue engineering ANALYTICAL METHODS. 5(1), 68-71 RAHMAN CV, KUHN G, WHITE LJ, KIRBY GTS, VARGHESE OP, MCLAREN JS, COX HC, ROSE FRAJ, MüLLER R, HILBORN J and SHAKESHEFF KM, 2013. PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties. Journal of biomedical materials research. Part B, Applied biomaterials. 101(4), 648-55 SAWKINS MJ, BOWEN W, DHADDA P, MARKIDES H, SIDNEY LE, TAYLOR AJ, ROSE FRAJ, BADYLAK SF, SHAKESHEFF KM and WHITE LJ, 2013. Hydrogels derived from demineralized and decellularized bone extracellular matrix. Acta biomaterialia. (In Press.) WATSON NJ, JOHAL RK, GLOVER Z, REINWALD Y, WHITE LJ, GHAEMMAGHAMI AM, MORGAN SP, ROSE FRAJ, POVEY MJW and PARKER NG, 2013. Post-processing of polymer foam tissue scaffolds with high power ultrasound: A route to increased pore interconnectivity, pore size and fluid transport. Materials science & engineering. C, Materials for biological applications. 33(8), 4825-32 HELEN HARRINGTON, FELICITY RJ ROSE, JONATHAN W AYLOTT and AMIR M. GHAEMMAGHAMI, 2013. Self-reporting Scaffolds for 3-Dimensional Cell Culture. Journal of Visualized Experiments. 81, e50608 RAHMAN CV, SMITH SJ, MORGAN PS, LANGMACK KA, CLARKE PA, RITCHIE AA, MACARTHUR DC, ROSE FR, SHAKESHEFF KM, GRUNDY RG and RUMAN RAHMAN, 2013. Adjuvant chemotherapy for brain tumors delivered via a novel intra-cavity moldable polymer matrix. PloS one. 8(10), e77435 HUYNH, N.T., HE, D., HAYES-GILL, B.R., CROWE, J.A., WALKER, J.G., MATHER, M.L., ROSE, F.R.A.J., PARKER, N.G., POVEY, M.J.W. and MORGAN, S.P., 2012. Application of a maximum likelihood algorithm to ultrasound modulated optical tomography Journal of Biomedical Optics. 17(2), 026014 SP MORGAN, FRAJ ROSE and SJ MATCHER, eds., 2012. Optical Techniques in Regenerative Medicine Taylor and Francis. (In Press.) DAVID Y S CHAU, SHERIDAN V BROWN, MELISSA MATHER, VICTORIA HUTTER, NAING L TINT, HARMINDER S DUA and FELICITY ROSE, 2012. Tissue transglutaminase (TG-2) modified amniotic membrane: a novel scaffold for biomedical applications Biomedical Materials. (In Press.)

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