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NURZY?SKA, KATARZYNA, AUSTIN, RUPERT P., FISCHER, PETER M., BOOTH, JONATHAN and GOMMER, FRANK, 2016. Survival of the Fittest: Time-To-Event Modeling of Crystallization of Amorphous Poorly Soluble Drugs: Journal of Pharmaceutical Sciences Journal of Pharmaceutical Sciences. 105(6), 1858-1866
EMTAGE, ABIGAIL L., MISTRY, SHAILESH N., FISCHER, PETER M., KELLAM, BARRIE and LAUGHTON, CHARLES A., 2016. GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors. Journal of biomolecular structure & dynamics. 1-16 (In Press.)
SOUKARIEH, FADI, NOWICKI, MATTHEW W., BASTIDE, AMANDINE, POYRY, TUIJA, JONES, CAROLYN, DUDEK, KATE, PATWARDHAN, GEETANJALI, MEULLENET, FRANCOIS, OLDHAM, NEIL J., WALKINSHAW, MALCOLM D., WILLIS, ANNE E. and FISCHER, PETER M., 2016. Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. European journal of medicinal chemistry. 124, 200-217
ZGAIR, ATHEER, WONG, JONATHAN CM, LEE, JONG BONG, MISTRY, JATIN, SIVAK, OLENA, WASAN, KISHOR M, HENNIG, IVO M, BARRETT, DAVID A, CONSTANTINESCU, CRIS S, FISCHER, PETER M and GERSHKOVICH, PAVEL, 2016. Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. American journal of translational research. 8(8), 3448-59
FRIDGEIRSDOTTIR GA, HARRIS R, FISCHER PM and ROBERTS CJ, 2016. Support Tools in Formulation Development for Poorly Soluble Drugs. Journal of Pharmaceutical Sciences. 105(8), 2260-9
FISCHER, PETER M., 2016. Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview Medicinal Research Reviews. (In Press.)
PATHAK M, WILMANN P, AWFORD J, LI C, HAMAD BK, FISCHER PM, DREVENY I, DEKKER LV and EMSLEY J, 2015. Coagulation factor XII protease domain crystal structure. Journal of thrombosis and haemostasis : JTH. 13(4), 580-591
HALLIDAY, M., RADFORD, H., SEKINE, Y., MORENO, J., VERITY, N., LE QUESNE, J., ORTORI, C. A., BARRETT, D. A., FROMONT, C., FISCHER, P. M., HARDING, H. P., RON, D. and MALLUCCI, G. R., 2015. Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity CELL DEATH & DISEASE. 6,
JADHAV, GOPAL P., KAUR, ISHWINDER, MARYATI, MARYATI, AIRHIHEN, BLESSING, FISCHER, PETER M. and WINKLER, G. SEBASTIAAN, 2015. Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1: Bioorganic & Medicinal Chemistry Letters Bioorganic & Medicinal Chemistry Letters. 25(19), 4219-4224
ZGAIR, ATHEER, WONG, JONATHAN C. M., SABRI, AKMAL, FISCHER, PETER M., BARRETT, DAVID A., CONSTANTINESCU, CRIS S. and GERSHKOVICH, PAVEL, 2015. Development of a simple and sensitive HPLC–UV method for the simultaneous determination of cannabidiol and Δ9-tetrahydrocannabinol in rat plasma: Journal of Pharmaceutical and Biomedical Analysis J. Pharm. Biomed. Anal.. 114(0), 145-151
SEKINE, Y., ZYRYANOVA, A., CRESPILLO-CASADO, A., FISCHER, P. M., HARDING, H. P. and RON, D., 2015. Mutations in a translation initiation factor identify the target of a memory-enhancing compound: Science Science. 348(6238), 1027-1030
NURZY?SKA, KATARZYNA, BOOTH, JONATHAN, ROBERTS, CLIVE J., MCCABE, JAMES, DRYDEN, IAN and FISCHER, PETER M., 2015. Long-Term Amorphous Drug Stability Predictions Using Easily Calculated, Predicted, and Measured Parameters: Molecular Pharmaceutics Molecular Pharmaceutics. 12(9), 3389-3398
CHEN, C.-H., GENAPATHY, S., FISCHER, P.M. and CHAN, W.C., 2014. A facile approach to tryptophan derivatives for the total synthesis of argyrin analogues Organic and Biomolecular Chemistry. 12(48), 9764-9768
LAM, F., ABBAS, A. Y., SHAO, H., TEO, T., ADAMS, J., LI, P., BRADSHAW, T. D., FISCHER, P. M., WALSBY, E., PEPPER, C., CHEN, Y., DING, J. and WANG, S., 2014. Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73: Oncotarget Oncotarget. 5(17), 7691-704
REDDY, T. R., LI, C., GUO, X., FISCHER, P. M. and DEKKER, L. V., 2014. Design, synthesis and SAR exploration of tri-substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction: Bioorg Med Chem Bioorg Med Chem. 22(19), 5378-91
MAZANETZ, M. P., LAUGHTON, C. A. and FISCHER, P. M., 2014. Investigation of the flexibility of protein kinases implicated in the pathology of Alzheimer's disease: Molecules Molecules. 19(7), 9134-59
MARYATI, M., KAUR, I., JADHAV, G. P., OLOTU-UMOREN, L., OVEH, B., HASHMI, L., FISCHER, P. M. and WINKLER, G. S., 2014. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity: Nucleic Acids Res Nucleic Acids Res. 42(5), e30
WALSBY, ELISABETH, PRATT, GUY, SHAO, HAO, ABBAS, ABDULLAH Y., FISCHER, PETER M., BRADSHAW, TRACEY D., BRENNAN, PAUL, FEGAN, CHRIS, WANG, SHUDONG and PEPPER, CHRIS, 2014. A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine: Oncotarget Oncotarget. 5, 375-385
SHAO, HAO, SHI, SHENHUA, HUANG, SHILIANG, HOLE, ALISON, ABBAS, ABDULLAHI Y., BAUMLI, SONJA, LIU, XIANGRUI, LAM, FRANKIE, FOLEY, DAVID W., FISCHER, PETER M., NOBLE, MARTIN, ENDICOTT, JANE A., PEPPER, CHRIS and WANG, SHUDONG, 2013. Substituted 4-(thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, x-ray crystal structure, SAR and anti-cancer activities: Journal of Medicinal Chemistry Journal of Medicinal Chemistry. 56, 640-659
MISTRY, S.N., BAKER, J.G., FISCHER, P.M., HILL, S.J., GARDINER, S.M. and KELLAM, B., 2013. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists Journal of Medicinal Chemistry. 56(10), 3852-3865
MORENO, J.A., HALLIDAY, M., MOLLOY, C., RADFORD, H., VERITY, N., AXTEN, J.M., ORTORI, C.A., WILLIS, A.E., FISCHER, P.M., BARRETT, D.A. and MALLUCCI, G.R., 2013. Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice: Science Translational Medicine Science Translational Medicine. 5(206), 206ra138
MARYATI M, KAUR I, JADHAV GP, OLOTU-UMOREN L, OVEH B, HASHMI L, FISCHER PM and WINKLER GS, 2013. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity. Nucleic acids research. (In Press.)
SHAO H, SHI S, FOLEY DW, LAM F, ABBAS AY, LIU X, HUANG S, JIANG X, BAHARIN N, FISCHER PM and WANG S, 2013. Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. European journal of medicinal chemistry. 70, 447-55
DICKENS MP, ROXBURGH P, HOCK A, MEZNA M, KELLAM B, VOUSDEN KH and FISCHER PM, 2013. 5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2. Bioorganic & medicinal chemistry. 21(22), 6868-77
LIU, XIANGRUI, LAM, FRANKIE, SHI, SHENHUA, FISCHER, PETER M and WANG, SHUDONG, 2012. In vitro antitumor mechanism of a novel cyclin-dependent kinase inhibitor CDKI-83. Investigational new drugs. 30(3), 889-897