个人简介
Studied pharmacy at the University of Heidelberg
1987 PhD, University of Heidelberg
1988-1999 Positions at Merck, Boehringer and Roche
Since 1999 Professor (C4) for Pharmaceutical Technology and Biopharmaceutics, LMU Munich
研究领域
Formulation and delivery of peptide and protein drugs
Colloidal drug carriers
Parenteral process technologies
近期论文
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A. Schmitt, P. Rödel, C. Anamur, C. Seeliger, A.B. Imhoff, E. Herbst, S. Vogt, M. van Griensven, G. Winter, J. Engert
Calcium alginate gels as stem cell matrix - making paracrine stem cell activity available for enhanced healing after surgery
PLoS One. 2015 Mar 20; 10(3):e0118937. doi:10.1371/journal.pone.0118937. eCollection 2015. PMID: 25793885 (Pubmed - in process)
M. Shomali, S. Tanriverdi, A.J. Freitag, J. Engert, G. Winter, M. Siedler, Z. Kaymakcalan, J.F. Carpenter, T.W. Randolph
Dose levels in particulate-containing formulations impact anti-drug antibody responses to murine monoclonal antibody in mice
J Pharm Sci. 2015 Mar 3. doi: 10.1002/jps.24413. (Epub ahead of print). PMID: 25737325 (PubMed - as supplied by publisher)
S. Horiuchi, G. Winter
CMC determination of nonionic surfactants in protein formulations using ultrasonic resonance technology
Eur J Pharm Biopharm. 2015 Feb 12. pii: S0939-6411(15)00062-4. doi: 10.1016/j.ejpb.2015.02.005. (Epub ahead of print). PMID: 25684280 (PubMed – as supplied by publisher)
C. Anamur, G. Winter, J. Engert
Stability of collapse lyophilized influenza vaccine formulations
Int J Pharm 2015 Feb 7. 483(1-2): 131-141. doi: 10.1016/j.ijpharm.2015.01.053. (Epub ahead of print). PMID: 25660049 (PubMed – as supplied by publisher)
M. Lucke, G. Winter, J. Engert
The effect of steam sterilization on recombinant spider silk particles
Int J Pharm.2015 Jan 14. pii: S0378-5173(15)00037-X. doi:10.1016/j.ijpharm.2015.01.024. (Epub ahead of print) PMID: 25596418 (PubMed- as supplied by publisher)
D.B. Volkin, S. Hershenson, R.J. Ho, S. Uchiyama, G. Winter, J.F. Carpenter
Two decades of publishing excellence in Pharmaceutical Biotechnology
J Pharm Sci. 2015 Feb; 104(2):290-300. doi: 10.1002/jps.24285 (Epub 2014 Dec 1)
PMID: 25448882 (PubMed – in process)
R. Liebner, M. Meyer, T. Hey, G. Winter, A. Besheer
Head to head comparison of the formulation and stability of concentrated solutions of HESylated versus PEGylated Anakinra
J Pharm Sci. 2015 Feb; 104(2):515-526 doi: 10.1002/jps.24253 (Epub 2014 Dec 1)
PMID: 25445200 (PubMed – in process)
R. Mathaes, G. Winter, A. Besheer, J. Engert
Non-spherical micro-and nanoparticles: fabrication, characterization and drug delivery applications
Expert Opin Drug Deliv. 2014 Oct 18:1-12. (Epub ahead of print)
PMID: 25327886 (PubMed – as supplied by publisher)
S.P. Hertel, G. Winter, W. Friess
Protein stability in pulmonary drug delivery via nebulization
Adv Drug Deliv Rev. 2014 Oct 10. pii:S0169-409X(14)00211-7. doi: 10.1016/j.addr.2014.10.003. (Epub ahead of print) Review. PMID: 25312674 (PubMed – as supplied by publisher)
C.G. Alexander, R. Wanner, C.M. Johnson, D. Breitsprecher, G. Winter, S. Duhr, P. Baaske, N. Ferguson
Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings
Biochim Biophys Acta. 2014 Sep 28; 1844(12):2241-2250. doi:10.1016/j.bbapap.2014.09.016. (Epub ahead of print). PMID: 25262836 (PubMed – as supplied by publisher)
N. Barapatre, P. Symvoulidis, W. Möller, F. Prade, N.C. Deliolanis, S. Hertel, G. Winter, A.O. Yildirim, T. Stoeger, O. Eickelberg, V. Ntziachristos, O. Schmid
Quantitative detection of drug dose and spatial distribution in the lung revealed by cryoslicing imaging
J Pharm Biomed Anal. 2014 Sep 8; 102C:129-136. doi: 10.1016/j.jpba.2014.09.001. Epub 2014 Sept 8
PMID: 25262414 (PubMed – in process)
B. Kneidl, M. Peller, G. Winter, L.H. Lindner, M. Hossann
Thermosensitive liposomal drug delivery systems: state of the art review
Int J Nanomedicine. 2014 Sep 16; 9:4387-4398. doi: 10.2147/IJN.S49297.eCollection 2014.
PMID: 25258529 (PubMed – in process)
A.J. Freitag, M. Shomali, S. Michalakis, M. Biel, M. Siedler, Z. Kaymakcalan, J.F. Carpenter, T.W. Randolph, G. Winter, J. Engert
Investigation of the immunogenicity of different types of aggregates of a murine monoclonal antibody in mice
Pharm. Res. 2014 Aug 15 (Epub 2014 Aug 15). PMID: 25123991 (PubMed- in process)
Y. Deng, R. Mathaes, G. Winter, J. Engert
Encapsulation of antigen-loaded silica nanoparticles into microparticles for intradermal powder injection
Eur J Pharm Sci. 2014 Oct 15. 63:154-166. doi: 10.1016/j.ejps.2014.07.004. Epub 2014 Jul 17. PMID: 25042055 (PubMed - in process)
M.Noga, D: Edinger, E. Wagner, G. Winter, A. Besheer
Characterization and compatibility of hydroxyethyl starch-polyethylenimine copolymers for DNA delivery
J Biomater Sci Polym Ed. 2014 Jun;25(9):855-871. doi: 10.1080/09205063.2014.910152.Epub 2014 May 2.
PMID: 24787557 (Pub-Med in process)
M. Noga, D. Edinger, E. Wagner, G. Winter, A. Besheer
Stability and activity of hydroxyethyl starch- coated polyplexes in frozen solutions or lyophilizates
Int J Pharm. 2014 Apr 9. pii: S0378-5173(14)00248-8. doi: 10.1016/j.ijpharm.2014.04.020. Epub 2014 Apr 13. PMID: 24727140 (PubMed- indexed for MEDLINE)
S. Hertel, T.Pohl, W. Friess, G. Winter
Prediction of protein degradation during vibrating mesh nebulization via a high throughput screening method
Eur J Pharm Biopharm. 2014 Apr 4. pii: S0939-6411(14)00116-7. doi: 10.1016/j.ejpb.2014.03.020. Epub 2014 Apr 4. PMID: 24709473 (PubMed – indexed for MEDLINE)
R. Liebner, R. Mathaes, M. Meyer, T. Hey, G. Winter, A. Besheer
Protein HESylation for half-life extension: Synthesis, characterization and pharmacokinetics of HESylated anakinra
Eur J Pharm Biopharm, 2014 Mar 27. pii: S0939-6411(14)00087-3. doi: 10.1016/j.ejpb.2014.03.010. Epub 2014 Mar 27. PMID: 24681396 (PubMed – indexed for MEDLINE)
S. Hertel, T. Pohl, W. Friess, G. Winter
That´s cool! – Nebulization of thermolabile proteins with a cooled vibrating mesh nebulizer
Eur J Pharm Biopharm. 2014 Mar 15. pii: S0939-6411(14)00078-2. doi: 10.1016/j.ejpb.2014.03.001. Epub 2014 Mar 15. PMID: 24662437 (PubMed – indexed for MEDLINE)
M.P. Even, K. Young, G. Winter, S. Hook, J. Engert
In vivo investigation of twin-screw extruded lipid implants for vaccine delivery
Eur J Pharm Biopharm. 2014 Mar 4. pii: S0939-6411(14)00074-5. doi: 10.1016/j.ejpb.2014.02.014. Epub 2014 Mar 4. PMID: 24607791 (PubMed – in dexed for MEDLINE)