Wagner, Ernst - Ludwig-Maximilians-Universität München

个人简介

1985 PhD in Chemistry at the Technical University of Vienna/Austria 1985-1987 Postdoctoral Researcher, ETH, Zurich/Switzerland 1988-1995 Group Leader, Institute of Molecular Pathology, Vienna/Austria 1992-2001, Director for Cancer Vaccines, Boehring

研究领域

pDNA, dsRNA and siRNA therapeutics Nanomedicine Oncology

近期论文

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Klein PM, Müller K, Gutmann C, Kos P, Krhac Levacic A, Edinger D, Höhn M, Leroux JC, Gauthier MA, Wagner E (2015) Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes, J Control Release. 2014 Dec 29. [Epub ahead of print] Kos, P., Lächelt, U., He, D., Nie, Y., Gu, Z., Wagner, E. (2015) Dual-Targeted Polyplexes Based on Sequence-Defined Peptide-PEG-Oligoaminoamides, J Pharm Sci. 2015 Feb;104(2):464-75 Lee, D.-J., Wagner, E., Lehto, T. (2015) Sequence-defined oligoaminoamides for the delivery of siRNAs, Methods Mol Biol. 2015;1206:15-27 Wagner, E. (2014) Polymers for Nucleic Acid Transfer — An Overview, Adv Genet. 2014;88:231-61 Lehto, T., Wagner, E. (2014) Sequence-defined polymers for the delivery of oligonucleotides, Nanomedicine (Lond). 2014 Dec;9(18):2843-59 Foerster F, Braig S, Moser C, Kubisch R, Busse J, Wagner E, Schmoeckel E, Mayr D, Schmitt S, Huettel S, Zischka H, Mueller R, Vollmar AM (2014) Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ, Cell Death Dis. 2014 Aug 28;5:e1398 Röder, R., Wagner, E. (2014) Sequence-defined shuttles for targeted nucleic acid and protein delivery, Ther Deliv. 2014 Sep;5(9):1025-45 Klein, P., Wagner, E. (2014) Bioreducible Polycations as Shuttles for Therapeutic Nucleic Acid and Protein Transfection, Antioxid Redox Signal. 2014 Aug 10;21(5):804-17 Lächelt U, Wittmann V, Müller K, Edinger D, Kos P, Höhn M, Wagner E (2014) Synthetic Polyglutamylation of Dual-Functional MTX Ligands for Enhanced Combined Cytotoxicity of Poly(I:C) Nanoplexes, Mol Pharm. 2014 Aug 4;11(8):2631-9 Wang Y, Wang K, Zhang R, Liu X, Yan X, Wang J, Wagner E, Huang R (2014) Synthesis of Core-Shell Graphitic Carbon@Silica Nanospheres with Dual-Ordered Mesopores for Cancer-Targeted Photothermochemotherapy, ACS Nano. 2014 Aug 26;8(8):7870-9 Wagner, E. (2014) Nucleic Acid Medicines: The Polymer Option. Encyclopedia of Polymeric Nanomaterials, DOI 10.1007/978-3-642-36199-9_267-1 Noga M, Edinger D, Wagner E, Winter G, Besheer A (2014) Stability and activity of hydroxyethyl starch-coated polyplexes in frozen solutions or lyophilizates, Int J Pharm. 2014 Jul 20;469(1):50-8 Noga M, Edinger D, Wagner E, Winter G, Besheer A (2014) Characterization and compatibility of hydroxyethyl starch-polyethylenimine copolymers for DNA delivery, J Biomater Sci Polym Ed. 2014;25(9):855-71 Edinger, D., Kläger, R., Troiber, C., Dohmen, C., Wagner, E. (2014) Gene Silencing and Antitumoral Effects of Eg5 or Ran siRNA Oligoaminoamide Polyplexes, Drug Deliv Transl Res 4 (1), 84-95 Salcher, E.E., Wagner, E. (2014) Nano-encapsulation of Oligonucleotides for Therapeutic Use, Nucleic Acid Nanotechnology, Nucleic Acids and Molecular Biology 29, 245-260 Schempp CM, von Schwarzenberg K, Schreiner L, Kubisch R, Müller R, Wagner E, Vollmar AM (2014) V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells, Mol Cancer Ther. 2014 Apr;13(4):926-37 Hütz, K., Mejías-Luque, R., Farkasova, K., Ogris, M., Krebs, S., Anton, M., Vieth, M., Schüller, U., Schneider, M.R., Blum, H., Wagner, E., Jung, A., Gerhard, M. (2014) The stem cell factor Sox2 regulates the tumorigenic potential in human gastric cancer cells, Carcinogenesis. 2014 Apr;35(4):942-50 Braig, S., Wiedmann, R. M., Liebl, J., Singer, M., Kubisch, R., Schreiner, L., Abhari, B. A., Wagner, E., Kazmaier, U., Fulda S., Vollmar, A. M. (2014) Pretubulysin: a new option for the treatment of metastatic cancer, Cell Death Dis. 2014 Jan 16;5:e1001 Kubisch R, Fröhlich T, Arnold GJ, Schreiner L, von Schwarzenberg K, Roidl A, Vollmar AM, Wagner E (2014) V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo, Int J Cancer. 2014 May 15;134(10):2478-88 Kopp F, Wagner E, Roidl A (2014) The proto-oncogene KRAS is targeted by miR-200c, Oncotarget. 2014 Jan;5(1):185-95