个人简介
现任四川大学华西药学院教授,博士生导师,国家优秀青年科学基金获得者,教育部新世纪优秀人才,四川省高级留学回国人员,四川省药学会副秘书长,四川省学术和技术带头人后备人选,兼任英国中央兰开夏大学访问研究员(Visiting Fellow)。
1991.9-1996.7 华西医科大学药学院本科
1996.8-2000.7 第一军医大学珠江医院
2000.9-2005.7 四川大学华西药学院攻读药剂学博士学位
2005.8-2007.2 美国宾夕法尼亚大学医学院博士后
2007.2-2008.9 美国密西根大学药学院博士后
2008.9-今 四川大学华西药学院教师
研究领域
1.药物及治疗基因传递系统。
2.分子药剂学: 从分子水平研究载体、药物,机体的相互作用。
近期论文
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Qin Zeng, Hao Jiang, Ting Wang, Zhirong Zhang, Tao Gong, Xun Sun*, Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses, Journal of Controlled Release, IF=7.261, 2015,200:1-12
Sanjun Shi, Lu Han, Li Deng, Yanling Zhang, Hongxin Shen, Tao Gong, Zhirong Zhang, Xun Sun*, Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression, Journal of Controlled Release, IF=7.261, 2014,194:228-237.
Zhaolu Xie, Zhonghua Ji, Zhirong Zhang, Tao Gong, Xun Sun*, Adenoviral vectors coated with cationic PEG derivatives for intravaginal vaccination against HIV-1, Biomaterials. IF= 8.312, 2014;35,7896-7908
Jianfeng Han , Qin Wang , Zhirong Zhang , Tao Gong , Xun Sun*, Cationic Bovine Serum Albumin Based Self-Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer. Small, IF=7.514, 2014, 10: 3524–3535
Sanjun Shi, Lu Han, Tao Gong, Zhirong Zhang, Xun Sun*, Systemic delivery of microRNA-34a for cancer stem cell therapy. Angewandte Chemie International Edition, IF=11.336, 2013,52:3901-3905.
Yu Wan, Jianfeng Han, Gerui Fan, Zhirong Zhang, Tao Gong, Xun Sun* Enzyme-responsive liposomes modified adenoviral vectors for enhanced tumor cell transduction and reduced immunogenicity Biomaterials. IF= 8.312, 2013;34,3020-3030
Yan Lin, Yanping Li, Xiaohong Wang, Tao Gong, Ling Zhang*, Xun Sun*. Targeted drug delivery to renal proximal tubule epithelial cells mediated by 2-glucosamine. Journal of Controlled Release, IF= 7.633, 2013,167:148–156
Qiang Peng, Zhi-Rong Zhang, Tao Gong, Guo-Qiang Chen,* Xun Sun,*A rapid-acting, long-acting insulin formulation based on a phospholipid complex loaded PHBHHx nanoparticles Biomaterials. IF= 7.404,2012;33,1583-1588
Hanmei Li, Hao Jiang, Mengnan Zhao, Yao Fu and Xun Sun*, Intracellular redox potential-responsive micelles based on polyethylenimine-cystaminepoly ( ε -caprolactone) block copolymer for enhanced miR-34a delivery, Polymer Chemistry, IF=5.368, 2015, 6, 1952–1960
Hanmei Li, Xun Sun*, Dong Zhao, Zhirong Zhang. A cell-specific Poly(ethylene glycol) Derivative with a wheat-like structure for efficient gene delivery. Molecular pharmaceutics. IF= 4.782,2012;9, 2974-2985.
Zhirong Zhong, Yu Wan, Sanjun Shi, Jianfeng Han, Zhirong Zhang, Xun Sun*. Co-delivery of Adenovirus and Carmustine by Anionic Liposomes with Synergistic Anti-tumor Effects. Pharmaceutical Research. IF= 4.093, 2012;29:145–157
SanJun Shi , ZhiRong Zhong , Jie Liu , ZhiRong Zhang, Xun Sun*, Tao Gong*. Solid Lipid Nanoparticles Loaded with Anti-microRNA Oligonucleotides (AMOs) for Suppression of MicroRNA-21 Functions in Human Lung Cancer Cells. Pharmaceutical Research. IF= 4.093, 2012;29:97-109
Zhirong Zhong, Jianfeng Han, Yu Wan, Zhirong Zhang, and Xun Sun*.Anionic Liposomes Enhance and Prolong Adenovirus-Mediated Gene Expression in Airway Epithelia in Vitro and in Vivo. Molecular pharmaceutics. IF=4.782, 2011;8(3):673-682.
Dong Zhao, Tao Gong, Di Zhu, Zhirong Zhang, Xun Sun?.Comprehensive comparison of two new biodegradable gene carriers. International Journal of Pharmaceutics. IF=3.350, 2011;413(1-2):260-270.