Hoffmann-Röder, Anja - Ludwig-Maximilians-Universität München

个人简介

Studied chemistry at the University of Bonn, Germany 2003 PhD, TU Dortmund, Germany 2003-2005 Postdoctoral research, ETH Zurich, Switzerland 2005-2006 Liebig-Fellow, University of Mainz, Germany 2006-2011 Emmy Noether junior research group (DFG),

研究领域

Synthesis of carbohydrates, peptides and glycokonjugates Tumor-associated carbohydrate antigens and cancer vaccines Glycomimetics and peptidomimetics for biological applications Fluorosugars, perfluorinated glycoconjugates

近期论文

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[41] Tom Podewin, Michael S. Rampp, Ilvana Turkanovic, Konstantin L. Karaghiosoff, Wolfgang Zinth and Anja Hoffmann-Röder, Photocontrolled chignolin-derived β-hairpin peptidomimetics; Chem. Commun. 2015, DOI: 10.1039/C4CC10304A. Manuel Johannes, Maximilian Reindl, Bastian Gerlitzki, Edgar Schmitt and Anja Hoffmann-Röder, Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4’-deoxy-4’-fluoro-Thomsen–Friedenreich epitope; Beilstein J. Org. Chem. 2015, 11, 155‒161; DOI: 10.3762/bjoc.11.15. Isabella Tavernaro, Sebastian Hartmann, Laura Sommer, Heike Hausmann, Christian Rohner, Martin Ruehl, Anja Hoffmann-Röder and Sabine Schlecht, Synthesis of tumor-associated MUC1-glycopeptides and their multivalent presentation by functionalized gold colloids; Org. Biomol. Chem. 2015, 13, 81‒97; DOI: 10.1039/C4OB01339E. Martin Scherer, Patrick Scheibe, Jérôme Schoenhentz, Anja Hoffmann-Röder, Rudolf Zentel, Patterned monomolecular films from polymerizable and fluorinated lipids for the presentation of glycosylated lipids; Colloid Polym. Sci. 2014; 292, 1803-1815; DOI: 10.1007/s00396-014-3237-5. Timo Schüler, Jochen Renkel, Stephan Hobe, Moritz Susewind, Dorrit E. Jacob, Martin Panthöfer, Anja Hoffmann-Röder, Harald Paulsen, Wolfgang Tremel, Designed Peptides for Biomineral Polymorph, Recognition: A Case Study for Calcium Carbonate; J. Mater. Chem. B 2014, 2, 3511-3518; DOI: 10.1039/C4TB00160E. Maximilian Reindl, Anja Hoffmann-Röder, Antibody Recognition of Fluorinated Haptens and Antigens; Curr. Topics Med. Chem. 2014, 14, 840-854, DOI: 10.2174/1568026614666140202203811. Amrei Deutsch, Herbert Glas, Anja Hoffmann-Röder, Carl Deutsch, Synthesis of functionalized a-trifluoroethylamine scaffolds via Grignard addition to N-aryl hemiaminal ethers; RSC Adv. 2014, 4, 9288−9291; DOI: 10.1039/C3RA47708H. Thomas Oberbillig, Holger Löwe, Anja Hoffmann-Röder, Synthesis of Fluorinated Glycosyl Amino Acid Building Blocks for MUC1 Cancer Vaccine Candidates by Microreactor-Assisted Glycosylation; J. Flow Chem. 2012, 2, 83−86; DOI: 10.1556/JFC-D-12-00011. Thomas Oberbillig, Christian Mersch, Sarah Wagner, Anja Hoffmann-Röder, Antibody recognition of fluorinated MUC1 glycopeptide antigens; Chem. Commun. 2012, 48, 1487−1489; DOI: 10.1039/C1CC15139H. Anja Hoffmann-Röder, Manuel Johannes, Synthesis of a MUC1-glycopeptide-BSA conjugate vaccine bearing the 3-deoxy-3-fluoro-Thomsen-Friedenreich antigen; Chem. Commun. 2011, 47, 9903‒9905; DOI: 10.1039/c1cc13184b. Tobias Platen, Timo Schüler, Wolfgang Tremel, Anja Hoffmann-Röder, Synthesis and antibody binding of highly fluorinated amphiphilic MUC1 glycopeptide antigens; Eur J. Org. Chem. 2011, 3878‒3887; DOI: 10.1002/ejoc.201100648. Manuel Johannes, Thomas Oberbillig, Anja Hoffmann-Röder, Synthesis of fluorinated Thomsen-Friedenreich antigens: direct deoxyfluorination of αGalNAc-threonine tert-butyl esters; Org. Biomol. Chem. 2011, 9, 5541‒5546; DOI: 10.1039/c1ob05373f. Anja Hoffmann-Röder, Jérôme Schoenhentz, Sarah Wagner, Edgar Schmitt, Perfluoroalkylated amphiphilic MUC1 glycopeptide antigens as tools for cancer immunotherapy; Chem. Commun. 2011, 47, 382‒384; DOI: 10.1039/c0cc02250k. Anja Hoffmann-Röder, Mirjam Hemmelmann, Patrick Scheibe, Jérôme Schoenhentz, Rudolf Zentel,Supramolekulare Systeme für die Tumorimmuntherapie; Natur & Geist 2010, 26, 38‒41. Patrick Scheibe, Jérôme Schoenhentz, Tobias Platen, Anja Hoffmann-Röder, Rudolf Zentel, Langmuir-Blodgett films of fluorinated glycolipids and polymerizable lipids and their phase separating behavior; Langmuir 2010,26, 18246‒18255; DOI: 10.1021/la1029917. Anja Hoffmann-Röder, Anton Kaiser, Sarah Wagner, Nikola Gaidzik, Danuta Kowalczyk, Ulrika Westerlind, Edgar Schmitt, Horst Kunz, Synthetische Antitumorvakzine aus Tetanus-Toxoid-Konjugaten von MUC1–Glycopeptiden mit Thomsen-Friedenreich-Antigen und dessen fluorsubstituiertem Analogon; Angew. Chem. 2010, 122, 8676‒8681; DOI: 10.1002/ange.201003810; Angew. Chem. Int. Ed. 2010, 49, 8498‒8503; DOI: 10.1002/anie.201003810. Sarah Wagner, Christian Mersch, Anja Hoffmann-Röder, Fluorinated glycosyl amino acids for mucin-like glycopeptide antigen analogues; Chem. Eur. J. 2010, 16, 7319‒7330; DOI: 10.1002/chem.200903294. Florian Karch, Anja Hoffmann-Röder, Synthesis of glycosylated β3-homo-threonine conjugates for mucin-like glycopeptide antigen analogues; Beilstein J. Org. Chem. 2010, 6, No 47; DOI: 10.3762/bjoc.6.47. Christian Mersch, Sarah Wagner, Anja Hoffmann-Röder, Synthesis of fluorinated analogues of tumor-associated carbohydrate and glycopeptide antigens; Synlett 2009, 2167‒2171; DOI: 10.1055/s-0029-1217566. Frank Volz, Sipke H. Wadman, Anja Hoffmann-Röder, Norbert Krause, Gold catalysis in stereoselective natural product synthesis: (+)-linalool oxide, (-)-isocyclocapitelline, and (-)-isochrysotricine"; Tetrahedron 2009, 65, 1902‒1910; DOI: 10.1016/j.tet.2008.11.104.