个人简介
1988 PhD at the Max-Planck-Institute for Developmental Biology, Tubingen
1989-1993 Postdoc at the University of California, Berkeley, USA
1993-1999 Assistant Professor at the Rockefeller University, New York, USA
2000-2009 Associate Professor at t
研究领域
To understand regulatory gene networks underlying organismal development and homeostasis at the systems level, using a combination of computational and experimental approaches.
To understand the role of glia in the development and adult homeostasis of t
近期论文
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Schroeder M, Greer C, and Gaul U (2011). How to make stripes - deciphering the transition from non-periodic to periodic patterns in Drosophila segmentation. Development 138, 3067-78.
Gaul U, (2010). Decoding transcription and microRNA-mediated translation control in Drosophila development. Biol Chem 391, 767-770.
Iovino N, Pane A, Gaul U (2009). miR-184 has multiple roles in Drosophila female germline development. Dev Cell 17, 123-133.
Sawyer JK, Harris NJ, Slep KC, Gaul U, and Peifer M (2009). The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction. J Cell Biol 186(1), 57-73.
Kurant E, Axelrod S, Leaman D, and Gaul U (2008). Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons. Cell 133, 498-509.
Segal E, Raveh-Sadka T, Schroeder M, Unnerstall U, and Gaul U (2008). Predicting expression patterns from regulatory sequence in Drosophila segmentation. Nature 451, 535-540.
Kertesz M, Iovino N, Unnerstall U, Gaul U*, Segal E* (2007). The role of site accessibility in microRNA target recognition. Nat Genet 39, 1278-1284.
Bainton R, Tsai LT, Schwabe T, DeSalvo M, Gaul U, Heberlein U (2005). moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila. Cell 123, 145-156.
Schwabe T, Bainton RJ, Fetter RD, Heberlein U, and Gaul U (2005). GPCR signaling is required for blood-brain barrier formation in Drosophila. Cell 123, 133-144.
Leaman D, Chen PY, Fak J, Yalcin A, Pearce M, Unnerstall U, Marks DS, Sander C, Tuschl T, and Gaul U (2005). Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell 121, 1097-1108.
Sinha S, Schroeder M, Unnerstall U, Gaul U, and Siggia ED (2004). Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila. BMC Bioinformatics 5:129.
Schroeder M, Pearce M, Fak J, Fan HQ, Unnerstall U, Emberly E, Rajewsky N, Siggia ED, and Gaul U (2004). Transcriptional control in the segmentation gene network of Drosophila. PLoS Biol 2:E271.
Enright AJ, John B, Gaul U, Tuschl T, Sander C, and Marks DS (2003). MicroRNA targets in Drosophila. Genome Biol 5:R1.
Boettner B, Harjes P, Ishimaru S, Heke M, Fan HQ, Qin Y, Van Aelst L, and Gaul U (2003). The AF-6 homolog Canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics 165, 159-169.
Rajewsky N, Vergassola M, Gaul U, and Siggia, ED (2002). Computational detection of genomic cis-regulatory modules, applied to body patterning in the early Drosophila embryo. BMC Bioinformatics 3:30.
Gaul U (2002). The establishment of retinal connectivity, in: Drosophila eye development (Results and problems in cell differentiation 37), K Moses, ed. (Heidelberg, Berlin: Springer Verlag), pp 205-218.
Rangarajan R, Courvoisier, H, and Gaul U (2001). Dpp and Hedgehog mediate neuron-glia interactions in Drosophila eye development by promoting the proliferation and motility of subretinal glia. Mech Dev 108, 93-103
Yagi R, Ishimaru S, Yano H, Gaul U, Hanafusa H, and Sabe H (2001) A novel muscle LIM-only protein is generated from the paxillin gene locus in Drosophila. EMBO Rep 2, 814-820.
Schmucker D, Vorbrueggen G, Yeghiayan, P, Fan, H Q, Jäckle H, and Gaul U (2000). The Drosophila gene abstrakt, required for visual system development, encodes a putative RNA helicase of the DEAD box protein family. Mech Dev 91, 189-196.
Rangarajan R, Gong, Q, and Gaul U (1999). Migration and function of glia in the developing Drosophila eye. Development 126, 3285-3292.